Development Level

Tbio 38 | 11,445
Tdark 11 | 6,588
Tchem 9 | 1,598
Tclin 5 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased total body fat amoun... 4 | 207
preweaning lethality, complete... 4 | 979
abnormal bone structure 3 | 187
increased bone mineral content 3 | 108
increased lean body mass 3 | 172
abnormal behavior 2 | 298
decreased caudal vertebrae num... 2 | 53
decreased circulating insulin ... 2 | 76
decreased circulating magnesiu... 2 | 13
decreased mean corpuscular hem... 2 | 50
decreased threshold for audito... 2 | 26
increased circulating alkaline... 2 | 122
increased startle reflex 2 | 112
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
abnormal tibia morphology 1 | 14
abnormal vitreous body morphol... 1 | 10
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
enlarged adrenal glands 1 | 3
enlarged kidney 1 | 14
enlarged uterus 1 | 11
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
irregularly shaped pupil 1 | 7
male infertility 1 | 123
polycystic kidney 1 | 15
short tibia 1 | 97
small kidney 1 | 16
small spleen 1 | 19
small testis 1 | 58
thrombocytopenia 1 | 56
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 47 | 11,493
ovarian cancer 38 | 8,520
glioblastoma 33 | 5,792
medulloblastoma, large-cell 32 | 6,241
osteosarcoma 31 | 7,950
psoriasis 30 | 6,694
atypical teratoid / rhabdoid tumor 29 | 5,112
ependymoma 28 | 4,679
adult high grade glioma 27 | 3,801
lung cancer 23 | 4,740
Breast cancer 22 | 3,578
group 3 medulloblastoma 19 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
oligodendroglioma 18 | 2,850
primitive neuroectodermal tumor 18 | 3,035
astrocytic glioma 17 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
malignant mesothelioma 17 | 3,232
Astrocytoma, Pilocytic 16 | 3,081
Kidney cancer 16 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
pituitary cancer 15 | 1,972
non-small cell lung cancer 14 | 2,890
invasive ductal carcinoma 13 | 2,951
lung carcinoma 13 | 2,843
subependymal giant cell astrocytoma 13 | 2,287
adrenocortical carcinoma 11 | 1,428
lung adenocarcinoma 11 | 2,716
pancreatic cancer 11 | 2,398
Schizophrenia 10 | 1,160
interstitial cystitis 10 | 2,312
tuberculosis 10 | 2,010
Pick disease 9 | 1,894
breast carcinoma 9 | 1,638
group 4 medulloblastoma 9 | 1,855
Cancer 8 | 2,499
Melanoma 8 | 711
colon cancer 8 | 1,478
ductal carcinoma in situ 8 | 1,745
Skin cancer 7 | 469
astrocytoma 7 | 1,146
cystic fibrosis 7 | 1,696
Acquired metabolic disease 6 | 336
Epilepsy 6 | 792
Intellectual disability 6 | 1,016
Multiple myeloma 6 | 1,332
cutaneous lupus erythematosus 6 | 1,057
dermatomyositis 6 | 966
juvenile dermatomyositis 6 | 1,187
ulcerative colitis 6 | 1,819
Autistic Disorder 5 | 364
Bipolar Disorder 5 | 666
Endometrial cancer 5 | 311
Type 2 diabetes mellitus 5 | 272
diabetes mellitus 5 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
Alzheimer's disease 4 | 658
Amyotrophic lateral sclerosis 4 | 451
Atopic dermatitis 4 | 952
Attention deficit hyperactivity disorder 4 | 278
Cardiovascular system disease 4 | 246
Obesity 4 | 678
Orbital separation excessive 4 | 244
Rheumatoid arthritis 4 | 1,191
Short stature 4 | 531
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
hepatocellular carcinoma 4 | 547
substance-related disorder 4 | 162
Autosomal recessive predisposition 3 | 1,442
Cerebrovascular disease 3 | 238
Cleft Palate 3 | 271
Crohn's disease 3 | 321
Depressive disorder 3 | 409
Down syndrome 3 | 499
Dull intelligence 3 | 645
Endometriosis 3 | 540
Hypertension 3 | 396
Hypertensive disease 3 | 292
Liver carcinoma 3 | 240
Low intelligence 3 | 645
Major Depressive Disorder 3 | 301
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Polycystic ovary syndrome 3 | 360
Poor school performance 3 | 645
Seizures 3 | 596
Small head 3 | 374
Unipolar Depression 3 | 250
Uranostaphyloschisis 3 | 167
active ulcerative colitis 3 | 764
aldosterone-producing adenoma 3 | 665
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
tuberculosis and treatment for 3 months 3 | 179

Tissue

Endocrine System 59 | 18,159
Female tissues 59 | 17,400
Skin and soft tissues 58 | 17,230
Urinary Tract 58 | 16,678
Liver and Pancreas 57 | 16,750
Nervous System 57 | 16,725
Digestive Tract 56 | 17,369
Male tissues 56 | 17,142
Respiratory system 56 | 16,393
Cardiovascular System 55 | 15,192
Blood and immune system 54 | 16,909

Target Family

Non-IDG 34 | 12,091
Enzyme 11 | 4,145
Kinase 6 | 634
GPCR 3 | 408
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Ion Channel 2 | 344
Transporter 1 | 473
oGPCR 1 | 421

GWAS Trait

Subjective well-being 63 | 63
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proline-rich protein 34 PRR34 Tdark Non-IDG 0.15 0.80 26
Limbic system-associated membrane protein LSAMP Tbio Non-IDG -1.72744 52.8 72
WD repeat-containing and planar cell polarity effector protein fritz homolog WDPCP Tbio Non-IDG -0.84019 7.08 68
Exosome complex exonuclease RRP44 DIS3 Tbio Enzyme -1.80730 64.2 141
Serine/threonine-protein kinase SIK3 SIK3 Tchem Kinase -1.18286 18.2 0
MAP kinase-interacting serine/threonine-protein kinase 2 MKNK2 Tchem Kinase -1.32729 19.5 234
Putative uncharacterized protein C16orf47 C16orf47 Tdark Non-IDG 0.00000 0
Autism susceptibility gene 2 protein AUTS2 Tbio Non-IDG -1.62719 42.8 79
Serine/threonine-protein kinase Nek1 NEK1 Tchem Kinase -1.62443 47.0 85
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396