Development Level

Tbio 26 | 11,445
Tdark 5 | 6,588
Tchem 4 | 1,598
Tclin 2 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal heart morphology 2 | 162
abnormal spleen morphology 2 | 55
abnormal vertebrae morphology 2 | 18
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
small testis 2 | 58
abnormal behavior 1 | 298
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased heart weight 1 | 27
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
enlarged seminal vesicle 1 | 10
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating serum al... 1 | 22
increased heart rate 1 | 23
increased mean corpuscular hem... 1 | 96
small kidney 1 | 16

Disease

Carcinoma 22 | 11,493
osteosarcoma 15 | 7,950
ovarian cancer 14 | 8,520
glioblastoma 13 | 5,792
psoriasis 12 | 6,694
lung adenocarcinoma 11 | 2,716
lung cancer 11 | 4,740
malignant mesothelioma 11 | 3,232
medulloblastoma, large-cell 11 | 6,241
adult high grade glioma 10 | 3,801
interstitial cystitis 10 | 2,312
group 3 medulloblastoma 9 | 4,104
invasive ductal carcinoma 9 | 2,951
lung carcinoma 9 | 2,843
Autosomal recessive predisposition 8 | 1,442
Breast cancer 8 | 3,578
Cancer 8 | 2,499
ependymoma 8 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
ulcerative colitis 8 | 1,819
Astrocytoma, Pilocytic 7 | 3,081
atypical teratoid / rhabdoid tumor 7 | 5,112
non-small cell lung cancer 7 | 2,890
pancreatic cancer 7 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
pituitary cancer 7 | 1,972
primitive neuroectodermal tumor 7 | 3,035
subependymal giant cell astrocytoma 7 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
oligodendroglioma 6 | 2,850
Crohn's disease 5 | 321
Epilepsy 5 | 792
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Kidney cancer 4 | 2,613
Multiple Sclerosis 4 | 540
Neurodegenerative disease 4 | 414
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
astrocytoma 4 | 1,146
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
gastric carcinoma 4 | 807
posterior fossa group A ependymoma 4 | 468
Amyotrophic lateral sclerosis 3 | 451
Asthma 3 | 385
Bipolar Disorder 3 | 666
Cerebrovascular disease 3 | 238
Cognitive delay 3 | 608
Dull intelligence 3 | 645
Feeding difficulties 3 | 127
Global developmental delay 3 | 608
Infantile onset 3 | 238
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Major Depressive Disorder 3 | 301
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Neuropathy 3 | 261
Nystagmus 3 | 317
Parkinson's disease 3 | 392
Pick disease 3 | 1,894
Poor school performance 3 | 645
Seizures 3 | 596
Systemic scleroderma 3 | 60
Type 1 diabetes mellitus 3 | 109
Unipolar Depression 3 | 250
Vitiligo 3 | 73
active ulcerative colitis 3 | 764
astrocytic glioma 3 | 2,597
group 4 medulloblastoma 3 | 1,855
interstitial lung disease 3 | 298
primary Sjogren syndrome 3 | 735
tuberculosis 3 | 2,010
Alzheimer's disease 2 | 658
Amphetamine-Related Disorders 2 | 74
Dementia 2 | 175
Depressive disorder 2 | 409
Duchenne muscular dystrophy 2 | 601
Failure to gain weight 2 | 365
Glaucoma 2 | 239
Hepatomegaly 2 | 285
Mental Depression 2 | 333
Muscle Spasticity 2 | 195
Pediatric failure to thrive 2 | 365
Prostate cancer 2 | 175
Psychotic Disorders 2 | 151
Status Epilepticus 2 | 98
Toxic encephalopathy 2 | 141
Waldenstrons macroglobulinemia 2 | 765
aldosterone-producing adenoma 2 | 665
chronic rhinosinusitis 2 | 512
esophageal adenocarcinoma 2 | 737
juvenile dermatomyositis 2 | 1,187
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic carcinoma 2 | 562
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Digestive Tract 34 | 17,369
Female tissues 34 | 17,400
Skin and soft tissues 34 | 17,230
Endocrine System 33 | 18,159
Male tissues 33 | 17,142
Blood and immune system 32 | 16,909
Liver and Pancreas 31 | 16,750
Urinary Tract 31 | 16,678
Respiratory system 30 | 16,393
Nervous System 29 | 16,725
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 23 | 12,091
Enzyme 10 | 4,145
Epigenetic 1 | 242
GPCR 1 | 408
Kinase 1 | 634
Transcription Factor 1 | 1,400

GWAS Trait

Strep throat 37 | 37
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proline-rich transmembrane protein 1 PRRT1 Tbio Non-IDG -1.33375 18.2 68
Ephrin type-B receptor 3 EPHB3 Tchem Kinase -1.68968 47.7 409
Psoriasis susceptibility 1 candidate gene 1 protein PSORS1C1 Tbio Non-IDG -0.99481 11.0 63
ERBB receptor feedback inhibitor 1 ERRFI1 Tbio Non-IDG -1.86682 77.3 148
Interleukin-1 receptor-like 1 IL1RL1 Tbio Non-IDG -2.06895 107.0 347
Tetratricopeptide repeat protein 7B TTC7B Tbio Non-IDG -0.38620 2.17 21
Protein piccolo PCLO Tbio Non-IDG -2.48756 308.4 124
Autophagy-related protein 16-1 ATG16L1 Tbio Non-IDG -2.26343 183.4 600
Cartilage matrix protein MATN1 Tbio Non-IDG -2.34188 216.4 173
Putative protein ATXN8OS ATXN8OS Tbio Non-IDG 0.00000 0