Development Level

Tbio 20 | 11,445
Tdark 10 | 6,588
Tchem 6 | 1,598
Tclin 1 | 613

Collection

RFA-RM-18-021 3 | 328
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

abnormal behavior 2 | 298
decreased grip strength 2 | 116
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal neural tube closure 1 | 46
abnormal tail morphology 1 | 25
cleft palate 1 | 8
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
embryonic growth retardation 1 | 106
hemorrhage 1 | 23
hyperactivity 1 | 148
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
male infertility 1 | 123
polycystic kidney 1 | 15

Disease

Carcinoma 31 | 11,493
ovarian cancer 22 | 8,520
osteosarcoma 20 | 7,950
atypical teratoid / rhabdoid tumor 18 | 5,112
glioblastoma 17 | 5,792
medulloblastoma, large-cell 17 | 6,241
Breast cancer 16 | 3,578
lung cancer 16 | 4,740
psoriasis 15 | 6,694
ependymoma 14 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Kidney cancer 10 | 2,613
adult high grade glioma 10 | 3,801
oligodendroglioma 10 | 2,850
astrocytic glioma 9 | 2,597
group 3 medulloblastoma 9 | 4,104
invasive ductal carcinoma 9 | 2,951
lung carcinoma 9 | 2,843
malignant mesothelioma 9 | 3,232
Pick disease 8 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
pituitary cancer 8 | 1,972
subependymal giant cell astrocytoma 8 | 2,287
Astrocytoma, Pilocytic 7 | 3,081
Cancer 7 | 2,499
non-small cell lung cancer 7 | 2,890
tuberculosis 7 | 2,010
cystic fibrosis 6 | 1,696
pancreatic cancer 6 | 2,398
primitive neuroectodermal tumor 6 | 3,035
Atopic dermatitis 5 | 952
Melanoma 5 | 711
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
gastric carcinoma 5 | 807
group 4 medulloblastoma 5 | 1,855
pediatric high grade glioma 5 | 1,064
Autosomal recessive predisposition 4 | 1,442
Obesity 4 | 678
adrenocortical carcinoma 4 | 1,428
cutaneous lupus erythematosus 4 | 1,057
interstitial cystitis 4 | 2,312
interstitial lung disease 4 | 298
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
Acquired metabolic disease 3 | 336
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Cerebrovascular disease 3 | 238
Duchenne muscular dystrophy 3 | 601
Endometrial cancer 3 | 311
Epilepsy 3 | 792
Liver cancer 3 | 604
Osteoporosis 3 | 363
Vascular disease 3 | 319
astrocytoma 3 | 1,146
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,478
lung adenocarcinoma 3 | 2,716
medulloblastoma 3 | 720
mucosa-associated lymphoid tissue lymphoma 3 | 484
pancreatic carcinoma 3 | 562
ulcerative colitis 3 | 1,819
Adult onset 2 | 82
Autism Spectrum Disorders 2 | 75
Autism spectrum disorder 2 | 101
Autistic Disorder 2 | 364
Barrett's esophagus 2 | 182
Bipolar Disorder 2 | 666
Cardiovascular system disease 2 | 246
Diarrhea 2 | 253
Dyslexia 2 | 43
Essential Hypertension 2 | 94
Gastroesophageal reflux disease 2 | 110
Liver Cirrhosis 2 | 181
Neurodegenerative disease 2 | 414
Osteoarthritis 2 | 184
Pitt-Hopkins syndrome 2 | 20
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Seizures 2 | 596
Skin cancer 2 | 469
Small cell carcinoma of lung 2 | 45
Thrombophilia 2 | 38
Ventricular Septal Defects 2 | 119
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
adrenocortical adenoma 2 | 131
cystic fibrosis and chronic rhinosinusitis 2 | 214
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
facioscapulohumeral dystrophy 2 | 288
hepatocellular carcinoma 2 | 547
limb girdle muscular dystrophy 2A 2 | 213
nasopharyngeal carcinoma 2 | 1,058
posterior fossa group A ependymoma 2 | 468

Tissue

Digestive Tract 35 | 17,369
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Nervous System 34 | 16,725
Urinary Tract 34 | 16,678
Blood and immune system 33 | 16,909
Liver and Pancreas 33 | 16,750
Skin and soft tissues 33 | 17,230
Male tissues 32 | 17,142
Respiratory system 31 | 16,393
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 9 | 4,145
Transcription Factor 5 | 1,400
Kinase 2 | 634
Transporter 2 | 473
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344

GWAS Trait

Stem cell growth factor beta l... 37 | 37
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Contactin-associated protein-like 2 CNTNAP2 Tbio Non-IDG -2.36156 228.4 191
Insulin-induced gene 1 protein INSIG1 Tbio Non-IDG -2.29727 186.9 147
Cilia- and flagella-associated protein 61 CFAP61 Tdark Non-IDG 0.48 0.25 43
Coagulation factor V F5 Tbio Non-IDG -2.73955 525.3 198
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.44791 277.6 405
Zinc finger protein 700 ZNF700 Tdark Transcription Factor 1.00 0.04 19
Zinc finger protein 788 ZNF788 Tdark Non-IDG 0.00000 0
Microtubule-associated protein 4 MAP4 Tbio Non-IDG -2.27689 185.8 253
Sodium-dependent phosphate transport protein 2A SLC34A1 Tbio Transporter -1.98345 87.1 65
Lysine-specific demethylase 4C KDM4C Tchem Epigenetic -1.64807 46.2 208