Development Level

Tbio 40 | 11,445
Tdark 16 | 6,588
Tchem 13 | 1,598
Tclin 2 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
increased total body fat amoun... 2 | 134
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal response to new envir... 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal tooth morphology 1 | 24
absent ovary 1 | 3
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
increased anti-nuclear antigen... 1 | 19
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
pale yolk sac 1 | 25
pallor 1 | 34
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 50 | 11,493
ovarian cancer 33 | 8,520
medulloblastoma, large-cell 29 | 6,241
glioblastoma 27 | 5,792
lung cancer 25 | 4,740
psoriasis 25 | 6,694
ependymoma 24 | 4,679
group 3 medulloblastoma 23 | 4,104
osteosarcoma 23 | 7,950
Breast cancer 22 | 3,578
atypical teratoid / rhabdoid tumor 22 | 5,112
adult high grade glioma 20 | 3,801
Astrocytoma, Pilocytic 18 | 3,081
lung carcinoma 17 | 2,843
primitive neuroectodermal tumor 17 | 3,035
oligodendroglioma 16 | 2,850
Cancer 15 | 2,499
Kidney cancer 15 | 2,613
Schizophrenia 13 | 1,160
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
lung adenocarcinoma 13 | 2,716
malignant mesothelioma 13 | 3,232
subependymal giant cell astrocytoma 13 | 2,287
astrocytic glioma 12 | 2,597
pancreatic cancer 12 | 2,398
ulcerative colitis 12 | 1,819
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
invasive ductal carcinoma 11 | 2,951
non-small cell lung cancer 11 | 2,890
cystic fibrosis 10 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Pick disease 9 | 1,894
adrenocortical carcinoma 9 | 1,428
pituitary cancer 9 | 1,972
Rheumatoid arthritis 8 | 1,191
astrocytoma 8 | 1,146
colon cancer 8 | 1,478
cutaneous lupus erythematosus 8 | 1,057
interstitial cystitis 8 | 2,312
Autosomal recessive predisposition 7 | 1,442
Type 1 diabetes mellitus 7 | 109
Breast Neoplasms 6 | 445
Liver cancer 6 | 604
diabetes mellitus 6 | 1,728
ductal carcinoma in situ 6 | 1,745
group 4 medulloblastoma 6 | 1,855
juvenile dermatomyositis 6 | 1,187
pediatric high grade glioma 6 | 1,064
Alzheimer's disease 5 | 658
Bipolar Disorder 5 | 666
Intellectual disability 5 | 1,016
Mammary Neoplasms 5 | 425
Multiple Sclerosis 5 | 540
Prostate cancer 5 | 175
Seizures 5 | 596
Vitiligo 5 | 73
active Crohn's disease 5 | 922
gastric cancer 5 | 459
hepatocellular carcinoma 5 | 547
nasopharyngeal carcinoma 5 | 1,058
non primary Sjogren syndrome sicca 5 | 891
tuberculosis 5 | 2,010
urothelial carcinoma 5 | 318
Chronic obstructive pulmonary disease 4 | 184
Epilepsy 4 | 792
Hypertension 4 | 396
Lung Neoplasms 4 | 232
Multiple myeloma 4 | 1,332
Prostatic Neoplasms 4 | 495
Short stature 4 | 531
Small head 4 | 374
breast carcinoma 4 | 1,638
esophageal adenocarcinoma 4 | 737
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
Acquired scoliosis 3 | 281
Atopic dermatitis 3 | 952
Broad flat nasal bridge 3 | 236
Byzanthine arch palate 3 | 194
Cognitive delay 3 | 608
Curvature of spine 3 | 282
Depressive disorder 3 | 409
Dull intelligence 3 | 645
Endometriosis 3 | 540
Global developmental delay 3 | 608
Kidney disease 3 | 430
Low intelligence 3 | 645
Mental Depression 3 | 333
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Nasal bridge wide 3 | 236
Nystagmus 3 | 317
Poor school performance 3 | 645
Type 2 diabetes mellitus 3 | 272
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
dermatomyositis 3 | 966
nephrosclerosis 3 | 333
primary Sjogren syndrome 3 | 735

Tissue

Endocrine System 66 | 18,159
Skin and soft tissues 65 | 17,230
Digestive Tract 64 | 17,369
Female tissues 64 | 17,400
Male tissues 64 | 17,142
Liver and Pancreas 63 | 16,750
Respiratory system 63 | 16,393
Urinary Tract 63 | 16,678
Blood and immune system 62 | 16,909
Nervous System 61 | 16,725
Cardiovascular System 60 | 15,192

Target Family

Non-IDG 37 | 12,091
Enzyme 10 | 4,145
Transcription Factor 8 | 1,400
Ion Channel 6 | 344
Kinase 4 | 634
oGPCR 3 | 421
Epigenetic 1 | 242
GPCR 1 | 408
Transporter 1 | 473

GWAS Trait

Squamous cell lung carcinoma 71 | 71
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pre-B-cell leukemia transcription factor 3 PBX3 Tbio Transcription Factor -1.58292 36.0 183
Pannexin-1 PANX1 Tbio Ion Channel -2.59888 418.5 154
Tripartite motif-containing protein 26 TRIM26 Tbio Non-IDG -0.84838 7.42 107
Protein furry homolog FRY Tbio Non-IDG -0.83463 6.61 30
Zinc finger protein 623 ZNF623 Tdark Transcription Factor 0.00000 47
Putative olfactory receptor 2W6 OR2W6P Tdark oGPCR 0.00000 0
Lysine-specific demethylase 4A KDM4A Tchem Epigenetic -3.06159 1089.8 271
Olfactory receptor 2J2 OR2J2 Tdark oGPCR 0.70 0.20 51
Keratin, type I cuticular Ha7 KRT37 Tdark Non-IDG -1.63304 35.5 15
Breast cancer type 2 susceptibility protein BRCA2 Tbio Non-IDG -3.46139 2647.6 209