Development Level

Tbio 23 | 11,651
Tdark 3 | 6,593
Tclin 2 | 612

IMPC Phenotype

abnormal behavior 1 | 298
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal eye anterior chamber ... 1 | 9
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
decreased circulating alkaline... 1 | 46
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased heart rate 1 | 23
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 21 | 11,493
ovarian cancer 13 | 8,520
psoriasis 13 | 6,694
Breast cancer 11 | 3,578
medulloblastoma, large-cell 11 | 6,241
osteosarcoma 11 | 7,950
glioblastoma 10 | 5,792
malignant mesothelioma 10 | 3,232
Cancer 9 | 2,499
ependymoma 9 | 4,679
lung carcinoma 9 | 2,843
group 3 medulloblastoma 8 | 4,104
lung cancer 8 | 4,740
Astrocytoma, Pilocytic 7 | 3,081
atypical teratoid / rhabdoid tumor 7 | 5,112
lung adenocarcinoma 7 | 2,716
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 2,010
ulcerative colitis 7 | 1,819
Asthma 6 | 385
non-small cell lung cancer 6 | 2,890
Crohn's disease 5 | 321
Hypersensitivity reaction type II disease 5 | 253
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
dermatomyositis 5 | 966
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
oligodendroglioma 5 | 2,850
Allergic hypersensitivity disease 4 | 126
Allergic rhinitis 4 | 95
Autosomal recessive predisposition 4 | 1,442
Type 1 diabetes mellitus 4 | 109
diabetes mellitus 4 | 1,728
primitive neuroectodermal tumor 4 | 3,035
spina bifida 4 | 1,074
Alopecia areata 3 | 41
Atopic dermatitis 3 | 952
Celiac disease 3 | 116
Common variable immunodeficiency 3 | 101
Kidney cancer 3 | 2,613
Lupus Erythematosus, Systemic 3 | 67
Pick disease 3 | 1,894
Pneumonia 3 | 174
Schizophrenia 3 | 1,160
cutaneous lupus erythematosus 3 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Acquired metabolic disease 2 | 336
Addison Disease 2 | 18
Adrenoleukodystrophy 2 | 29
Alzheimer's disease 2 | 658
Arthritis, Juvenile 2 | 126
Bipolar Disorder 2 | 666
Blepharoptosis 2 | 231
Byzanthine arch palate 2 | 194
Chondrodysplasia punctata 2 | 41
Developmental regression 2 | 95
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Hepatomegaly 2 | 285
Hypereosinophilic syndrome 2 | 71
Infantile Refsum disease 2 | 23
Inflammatory bowel disease 2 | 151
Juvenile arthritis 2 | 126
Kidney disease 2 | 430
Liver Cirrhosis 2 | 181
Loss of developmental milestones 2 | 95
Low Vision 2 | 174
Major Depressive Disorder 2 | 301
Mental deterioration in childhood 2 | 95
Multiple Sclerosis 2 | 540
Neurodevelopmental regression 2 | 95
Pediatric failure to thrive 2 | 365
Peroxisomal disease 2 | 22
Psychomotor regression 2 | 95
Psychomotor regression beginning in infancy 2 | 95
Psychomotor regression in infants 2 | 95
Psychomotor regression, progressive 2 | 95
Refsum disease 2 | 20
Sensorineural Hearing Loss (disorder) 2 | 284
Systemic lupus erythematosus 2 | 194
Unipolar Depression 2 | 250
Visual Impairment 2 | 174
Waldenstrons macroglobulinemia 2 | 765
Zellweger syndrome 2 | 37
active Crohn's disease 2 | 922
acute quadriplegic myopathy 2 | 1,158
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
cystic fibrosis and chronic rhinosinusitis 2 | 214
esophageal adenocarcinoma 2 | 737
hepatocellular carcinoma 2 | 547
mucosa-associated lymphoid tissue lymphoma 2 | 484
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
substance-related disorder 2 | 162

Tissue

Endocrine System 27 | 18,159
Blood and immune system 25 | 16,909
Digestive Tract 25 | 17,369
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Respiratory system 25 | 16,393
Urinary Tract 25 | 16,678
Nervous System 24 | 16,725
Skin and soft tissues 24 | 17,230
Cardiovascular System 23 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 5 | 4,145
Transcription Factor 4 | 1,400

GWAS Trait

Self-reported allergy 28 | 28
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-21 receptor IL21R Tbio Non-IDG -1.91843 79.5 328
Tetratricopeptide repeat protein 6 TTC6 Tdark Non-IDG 0.27 0.57 63
DNA-binding protein Ikaros IKZF1 Tbio Transcription Factor -2.66732 483.6 400
Interleukin-2 receptor subunit alpha IL2RA Tclin Non-IDG -3.02107 927.8 1917
Mothers against decapentaplegic homolog 3 SMAD3 Tbio Transcription Factor -3.19667 1403.6 1526
WD repeat-containing protein 36 WDR36 Tbio Non-IDG -1.71695 52.0 29
Interleukin-4 receptor subunit alpha IL4R Tclin Non-IDG -2.25138 150.9 462
Phytanoyl-CoA dioxygenase, peroxisomal PHYH Tbio Enzyme -2.34936 221.5 300
Ran-binding protein 6 RANBP6 Tdark Non-IDG 0.49 0.40 74
Ran GTPase-activating protein 1 RANGAP1 Tbio Enzyme -1.84078 65.7 254