Development Level

Tbio 221 | 10,625
Tdark 52 | 7,003
Tchem 45 | 1,890
Tclin 16 | 602

Collection

Eligible Ion Channel Proteins 5 | 117
Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 15 | 633
preweaning lethality, incomple... 11 | 260
abnormal behavior 10 | 226
decreased bone mineral density 6 | 126
decreased grip strength 6 | 123
embryonic lethality prior to t... 6 | 187
abnormal lens morphology 5 | 73
hyperactivity 5 | 108
increased or absent threshold ... 5 | 128
decreased circulating insulin ... 4 | 75
decreased prepulse inhibition 4 | 52
decreased total body fat amoun... 4 | 186
increased bone mineral density 4 | 52
abnormal bone structure 3 | 131
abnormal embryo size 3 | 112
abnormal retina morphology 3 | 100
decreased body length 3 | 108
decreased bone mineral content 3 | 157
decreased circulating serum al... 3 | 79
decreased heart weight 3 | 44
decreased lean body mass 3 | 195
increased exploration in new e... 3 | 56
increased grip strength 3 | 83
abnormal bone mineralization 2 | 55
abnormal cornea morphology 2 | 24
abnormal eye morphology 2 | 38
abnormal forebrain development 2 | 18
abnormal hindbrain development 2 | 24
abnormal locomotor activation 2 | 26
abnormal midbrain development 2 | 22
abnormal neural tube closure 2 | 37
abnormal retinal blood vessel ... 2 | 18
abnormal retinal pigmentation 2 | 61
abnormal spinal cord morpholog... 2 | 8
abnormal spleen morphology 2 | 36
abnormal startle reflex 2 | 14
abnormal vocalization 2 | 21
absent heartbeat 2 | 6
decreased body weight 2 | 174
decreased cervical vertebrae n... 2 | 12
decreased circulating HDL chol... 2 | 77
decreased circulating aspartat... 2 | 27
decreased circulating choleste... 2 | 85
decreased eosinophil cell numb... 2 | 41
decreased erythrocyte cell num... 2 | 43
decreased hemoglobin content 2 | 53
decreased startle reflex 2 | 48
embryonic lethality prior to o... 2 | 148
enlarged lymph nodes 2 | 27
enlarged spleen 2 | 26
female infertility 2 | 34
hypoactivity 2 | 89
increased circulating HDL chol... 2 | 63
increased circulating iron lev... 2 | 25
increased erythrocyte cell num... 2 | 26
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
increased vertical activity 2 | 18
prenatal lethality prior to he... 2 | 64
thrombocytopenia 2 | 46
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal cranium morphology 1 | 32
abnormal defecation 1 | 1
abnormal iris morphology 1 | 12
abnormal limb bud morphology 1 | 15
abnormal respiratory quotient 1 | 9
abnormal sensory capabilities/... 1 | 3
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
absent pinna reflex 1 | 21
absent teeth 1 | 4
cataract 1 | 26
corneal opacity 1 | 25
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased exploration in new e... 1 | 9
decreased gamma-delta T cell n... 1 | 18
decreased hematocrit 1 | 25
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased pulmonary respirator... 1 | 4
decreased total retina thickne... 1 | 20
dilated heart left ventricle 1 | 10
impaired righting response 1 | 19
increased CD4-positive, CD25-p... 1 | 18
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased circulating alanine ... 1 | 11
increased circulating choleste... 1 | 53
increased circulating glycerol... 1 | 11
increased gamma-delta T cell n... 1 | 16
increased rib number 1 | 41
increased startle reflex 1 | 38
long tibia 1 | 13
pallor 1 | 13
persistence of hyaloid vascula... 1 | 22
small superior vagus ganglion 1 | 20
straub tail 1 | 26

Disease

medulloblastoma, large-cell 175 | 6,234
ovarian cancer 168 | 8,484
osteosarcoma 159 | 7,933
glioblastoma 153 | 5,572
atypical teratoid / rhabdoid tumor 143 | 4,369
psoriasis 143 | 6,685
pilocytic astrocytoma 113 | 3,086
Schizophrenia 112 | 501
Carcinoma 110 | 2,147
oligodendroglioma 98 | 2,849
lung cancer 97 | 4,466
primitive neuroectodermal tumor 92 | 3,031
ependymoma 88 | 2,514
Breast cancer 87 | 3,094
astrocytic glioma 84 | 2,241
lung carcinoma 79 | 2,844
subependymal giant cell astrocytoma 79 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 77 | 2,956
pediatric high grade glioma 77 | 2,712
malignant mesothelioma 74 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 73 | 3,289
lung adenocarcinoma 72 | 2,713
adult high grade glioma 67 | 2,148
Pick disease 66 | 1,893
non-small cell lung cancer 66 | 2,798
pituitary cancer 66 | 1,972
group 4 medulloblastoma 65 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 62 | 2,988
invasive ductal carcinoma 60 | 2,950
interstitial cystitis 58 | 2,299
group 3 medulloblastoma 49 | 2,254
colon cancer 48 | 1,475
medulloblastoma 46 | 1,524
ulcerative colitis 46 | 2,087
cystic fibrosis 45 | 1,665
posterior fossa group A ependymoma 45 | 1,511
pancreatic cancer 42 | 2,300
Cancer 41 | 2,346
astrocytoma 39 | 1,493
adrenocortical carcinoma 35 | 1,427
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,795
posterior fossa group B ependymoma 35 | 1,530
tuberculosis 34 | 1,557
sonic hedgehog group medulloblastoma 33 | 1,482
acute quadriplegic myopathy 32 | 1,157
Bipolar Disorder 30 | 266
Rheumatoid Arthritis 30 | 1,160
breast carcinoma 30 | 1,614
ductal carcinoma in situ 29 | 1,745
aldosterone-producing adenoma 27 | 664
Autistic Disorder 26 | 320
Obesity 26 | 616
spina bifida 26 | 1,064
cutaneous lupus erythematosus 24 | 1,056
primary pancreatic ductal adenocarcinoma 24 | 1,271
Epilepsy 22 | 346
Alzheimer's disease 21 | 644
diabetes mellitus 21 | 1,663
juvenile dermatomyositis 21 | 1,189
Acquired metabolic disease 20 | 267
active Crohn's disease 20 | 918
atypical teratoid/rhabdoid tumor 20 | 1,095
non-small cell lung carcinoma 20 | 413
Intellectual disability 19 | 573
acute myeloid leukemia 18 | 780
primary Sjogren syndrome 18 | 789
progressive supranuclear palsy 18 | 674
gastric carcinoma 17 | 832
tuberculosis and treatment for 6 months 17 | 686
Multiple myeloma 16 | 1,327
dermatomyositis 15 | 933
hereditary spastic paraplegia 15 | 313
non primary Sjogren syndrome sicca 15 | 840
Atopic dermatitis 14 | 944
Chronic Lymphocytic Leukemia 14 | 242
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 499
nasopharyngeal carcinoma 14 | 1,056
Amyotrophic Lateral Sclerosis 13 | 431
chronic rhinosinusitis 13 | 512
glioblastoma multiforme 13 | 347
Down syndrome 12 | 548
Melanoma 12 | 261
Substance-Related Disorders 12 | 114
Vascular disease 12 | 281
Waldenstrons macroglobulinemia 12 | 765
Crohn's disease 11 | 304
Heart disease 11 | 279
esophageal adenocarcinoma 11 | 737
tuberculosis and treatment for 3 months 11 | 327
Amphetamine-Related Disorders 10 | 74
Osteoporosis 10 | 257
Peripheral Neuropathy 10 | 303
Type 2 diabetes mellitus 10 | 189
Vitiligo 10 | 71
Asthma 9 | 349
Attention deficit hyperactivity disorder 9 | 156
Endometriosis 9 | 535
Multiple Sclerosis 9 | 498
Prostate cancer 9 | 172
Prostatic Neoplasms 9 | 471

Tissue

Digestive Tract 331 | 18,473
Liver and Pancreas 331 | 18,136
Nervous System 331 | 18,561
Urinary Tract 331 | 18,444
Endocrine System 330 | 18,512
Female tissues 330 | 18,647
Cardiovascular System 329 | 17,958
Male tissues 328 | 17,969
Skin and soft tissues 328 | 18,115
Blood and immune system 327 | 17,995
Respiratory system 327 | 17,484

Target Family

Non-IDG 177 | 11,971
Enzyme 74 | 4,146
Transcription Factor 29 | 1,400
Kinase 20 | 634
Ion Channel 15 | 341
Transporter 8 | 473
GPCR 5 | 406
Epigenetic 4 | 242
Nuclear Receptor 2 | 48

GWAS Trait

Schizophrenia 334 | 334
Obesity-related traits 380 | 380
Height 250 | 250
Post bronchodilator FEV1/FVC r... 192 | 192
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 112 | 112
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1/FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
VPS10 domain-containing receptor SorCS3 SORCS3 Tbio Non-IDG -0.54622 5.51 46
N-acylglucosamine 2-epimerase RENBP Tbio Enzyme -1.52686 33.5 80
Inactive phospholipase C-like protein 2 PLCL2 Tbio Enzyme -0.27372 2.11 81
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
Zinc finger protein 536 ZNF536 Tdark Transcription Factor -0.17194 1.30 69
Mitochondrial ribonuclease P protein 3 KIAA0391 Tbio Enzyme 66.3 56
PH and SEC7 domain-containing protein 3 PSD3 Tbio Non-IDG -1.18771 15.6 120
Contactin-associated protein-like 5 CNTNAP5 Tdark Non-IDG -0.52403 3.89 4
Lipoma-preferred partner LPP Tbio Non-IDG -2.68601 520.6 153
Transmembrane protein 132D TMEM132D Tbio Non-IDG -2.20806 159.4 59