Development Level

Tbio 18 | 11,445
Tdark 7 | 6,588
Tchem 5 | 1,598
Tclin 3 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

enlarged heart 3 | 210
abnormal behavior 2 | 298
abnormal seminal vesicle morph... 2 | 114
decreased vertical activity 2 | 208
increased circulating alkaline... 2 | 122
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal skin condition 1 | 6
abnormal skin pigmentation 1 | 1
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating sodium l... 1 | 22
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased thermal nociceptive ... 1 | 2
increased anti-nuclear antigen... 1 | 19
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 26 | 11,493
ovarian cancer 17 | 8,520
osteosarcoma 13 | 7,950
Kidney cancer 11 | 2,613
ependymoma 11 | 4,679
glioblastoma 11 | 5,792
medulloblastoma, large-cell 11 | 6,241
atypical teratoid / rhabdoid tumor 10 | 5,112
group 3 medulloblastoma 10 | 4,104
pancreatic cancer 10 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Breast cancer 8 | 3,578
lung cancer 8 | 4,740
malignant mesothelioma 8 | 3,232
psoriasis 8 | 6,694
breast carcinoma 7 | 1,638
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
non-small cell lung cancer 7 | 2,890
primitive neuroectodermal tumor 7 | 3,035
Autosomal recessive predisposition 6 | 1,442
Liver cancer 6 | 604
Pick disease 6 | 1,894
adult high grade glioma 6 | 3,801
astrocytic glioma 6 | 2,597
colon cancer 6 | 1,478
ductal carcinoma in situ 6 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
oligodendroglioma 6 | 2,850
Astrocytoma, Pilocytic 5 | 3,081
Rheumatoid arthritis 5 | 1,191
cystic fibrosis 5 | 1,696
lung adenocarcinoma 5 | 2,716
nasopharyngeal carcinoma 5 | 1,058
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
Cancer 4 | 2,499
cutaneous lupus erythematosus 4 | 1,057
diabetes mellitus 4 | 1,728
gastric carcinoma 4 | 807
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 658
Atopic dermatitis 3 | 952
Down syndrome 3 | 499
Endometriosis 3 | 540
Multiple myeloma 3 | 1,332
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
Seizures 3 | 596
Type 2 diabetes mellitus 3 | 272
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
fibroadenoma 3 | 559
group 4 medulloblastoma 3 | 1,855
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
mucosa-associated lymphoid tissue lymphoma 3 | 484
progressive supranuclear palsy 3 | 676
ulcerative colitis 3 | 1,819
Alcoholic Intoxication, Chronic 2 | 289
Amphetamine-Related Disorders 2 | 74
Attention deficit hyperactivity disorder 2 | 278
Bipolar Disorder 2 | 666
Breast Neoplasms 2 | 445
Chronic Lymphocytic Leukemia 2 | 262
Diarrhea 2 | 253
Dull intelligence 2 | 645
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Feeding difficulties in infancy 2 | 175
Fever 2 | 138
Hypertension 2 | 396
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Low intelligence 2 | 645
Mammary Neoplasms 2 | 425
Mental Depression 2 | 333
Mental deficiency 2 | 645
Neurodegenerative disease 2 | 414
Pediatric failure to thrive 2 | 365
Polycystic ovary syndrome 2 | 360
Poor school performance 2 | 645
Recurrent respiratory infections 2 | 141
Short stature 2 | 531
Vascular disease 2 | 319
Vomiting 2 | 116
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
head and neck cancer 2 | 271
hepatocellular carcinoma 2 | 547
nephrosclerosis 2 | 333
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
urothelial carcinoma 2 | 318

Tissue

Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Male tissues 33 | 17,142
Skin and soft tissues 33 | 17,230
Female tissues 32 | 17,400
Nervous System 32 | 16,725
Blood and immune system 31 | 16,909
Liver and Pancreas 31 | 16,750
Respiratory system 31 | 16,393
Urinary Tract 31 | 16,678
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 12 | 4,145
Kinase 2 | 634
GPCR 1 | 408
Ion Channel 1 | 344
Transcription Factor 1 | 1,400
Transporter 1 | 473

GWAS Trait

Scarlet fever 33 | 33
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine deaminase GDA Tbio Enzyme -1.48687 32.3 196
Butyrophilin-like protein 2 BTNL2 Tbio Non-IDG -2.57312 369.3 73
Junctophilin-3 JPH3 Tbio Non-IDG -1.51901 34.8 165
Cadherin EGF LAG seven-pass G-type receptor 1 CELSR1 Tbio GPCR -1.47924 34.4 115
Choline transporter-like protein 4 SLC44A4 Tbio Transporter -1.67656 44.1 28
Receptor-type tyrosine-protein phosphatase N2 PTPRN2 Tbio Enzyme -2.46190 287.4 307
Beta-mannosidase MANBA Tchem Enzyme -2.02551 103.8 50
Bone morphogenetic protein receptor type-1B BMPR1B Tchem Kinase -2.00303 86.8 498
Protein sidekick-2 SDK2 Tdark Non-IDG -0.42720 2.61 17
Arginyl-tRNA--protein transferase 1 ATE1 Tbio Enzyme -1.88963 77.4 132