Development Level

Tbio 79 | 11,445
Tdark 18 | 6,588
Tchem 15 | 1,598
Tclin 9 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
abnormal retina morphology 3 | 71
abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
abnormal eye morphology 2 | 68
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral content 2 | 151
decreased circulating glucose ... 2 | 126
decreased lean body mass 2 | 135
decreased monocyte cell number 2 | 8
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased circulating sodium l... 2 | 71
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
small superior vagus ganglion 2 | 74
abnormal colon morphology 1 | 3
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal duodenum morphology 1 | 4
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal forebrain morphology 1 | 10
abnormal head morphology 1 | 10
abnormal incisor morphology 1 | 4
abnormal locomotor behavior 1 | 24
abnormal pancreas morphology 1 | 13
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
absent vibrissae 1 | 12
anophthalmia 1 | 33
cyanosis 1 | 7
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased respiratory quotient 1 | 16
decreased threshold for audito... 1 | 26
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged testis 1 | 6
female infertility 1 | 60
fusion of vertebral arches 1 | 7
hemorrhage 1 | 23
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased CD4-positive, alpha ... 1 | 4
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
male infertility 1 | 123
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
prolonged ST segment 1 | 36
small testis 1 | 58
tremors 1 | 39
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 84 | 11,493
osteosarcoma 74 | 7,950
Rheumatoid arthritis 67 | 1,191
ovarian cancer 54 | 8,520
psoriasis 50 | 6,694
glioblastoma 45 | 5,792
lung cancer 44 | 4,740
medulloblastoma, large-cell 42 | 6,241
Arthritis, Rheumatoid 34 | 174
ependymoma 33 | 4,679
lung carcinoma 33 | 2,843
interstitial cystitis 31 | 2,312
Cancer 30 | 2,499
atypical teratoid / rhabdoid tumor 29 | 5,112
malignant mesothelioma 28 | 3,232
tuberculosis 27 | 2,010
Crohn's disease 26 | 321
group 3 medulloblastoma 26 | 4,104
primitive neuroectodermal tumor 26 | 3,035
adult high grade glioma 25 | 3,801
lung adenocarcinoma 25 | 2,716
ulcerative colitis 25 | 1,819
Astrocytoma, Pilocytic 24 | 3,081
non-small cell lung cancer 24 | 2,890
Hypersensitivity reaction type II disease 23 | 253
astrocytic glioma 21 | 2,597
invasive ductal carcinoma 21 | 2,951
Breast cancer 20 | 3,578
Systemic lupus erythematosus 20 | 194
Type 1 diabetes mellitus 20 | 109
diabetes mellitus 20 | 1,728
oligodendroglioma 20 | 2,850
subependymal giant cell astrocytoma 19 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
pancreatic cancer 18 | 2,398
Multiple Sclerosis 16 | 540
cutaneous lupus erythematosus 16 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
cystic fibrosis 15 | 1,696
primary Sjogren syndrome 15 | 735
Asthma 14 | 385
Lupus Erythematosus, Systemic 14 | 67
Schizophrenia 13 | 1,160
Celiac disease 12 | 116
Juvenile rheumatoid arthritis 12 | 111
Pick disease 12 | 1,894
pituitary cancer 12 | 1,972
Kidney cancer 11 | 2,613
Systemic scleroderma 11 | 60
Vitiligo 11 | 73
Arthralgia 10 | 90
Autosomal recessive predisposition 10 | 1,442
breast carcinoma 10 | 1,638
ductal carcinoma in situ 10 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Alopecia areata 9 | 41
Anti-nuclear factor positive 9 | 18
Bipolar Disorder 9 | 666
Liver Cirrhosis, Experimental 9 | 769
active ulcerative colitis 9 | 764
colon cancer 9 | 1,478
juvenile dermatomyositis 9 | 1,187
Apraxias 8 | 27
C-reactive protein increased 8 | 15
ESR raised 8 | 20
Elevated C-reactive protein level 8 | 15
Juvenile rheumatoid factor-negative polyarthritis 8 | 9
Oligoarticular juvenile arthritis 8 | 9
Pauciarticular juvenile rheumatoid arthritis 8 | 9
group 4 medulloblastoma 8 | 1,855
medulloblastoma 8 | 720
sarcoidosis 8 | 370
Angle class 2 malocclusion 7 | 57
Angle class 3 malocclusion 7 | 57
Atherosclerosis 7 | 291
Autoimmune Diseases 7 | 67
Biliary cirrhosis 7 | 45
Common variable immunodeficiency 7 | 101
Decreased joint mobility 7 | 53
Immunologic Deficiency Syndromes 7 | 113
Intellectual disability 7 | 1,016
Iridocyclitis 7 | 19
Joint swelling 7 | 26
Major Depressive Disorder 7 | 301
Malocclusion 7 | 57
Melanoma 7 | 711
Polyarthritis 7 | 11
Primary biliary cirrhosis 7 | 51
acute myeloid leukemia 7 | 783
dermatomyositis 7 | 966
pediatric high grade glioma 7 | 1,064
Connective tissue disease 6 | 62
Down syndrome 6 | 499
acute quadriplegic myopathy 6 | 1,158
aldosterone-producing adenoma 6 | 665
astrocytoma 6 | 1,146
esophageal adenocarcinoma 6 | 737
hepatocellular carcinoma 6 | 547
spina bifida 6 | 1,074

Tissue

Male tissues 119 | 17,142
Digestive Tract 118 | 17,369
Endocrine System 118 | 18,159
Blood and immune system 117 | 16,909
Skin and soft tissues 117 | 17,230
Female tissues 116 | 17,400
Respiratory system 114 | 16,393
Liver and Pancreas 113 | 16,750
Urinary Tract 113 | 16,678
Nervous System 107 | 16,725
Cardiovascular System 105 | 15,192

Target Family

Non-IDG 75 | 12,091
Enzyme 22 | 4,145
Transcription Factor 13 | 1,400
Kinase 6 | 634
GPCR 2 | 408
Epigenetic 1 | 242
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

GWAS Trait

Rheumatoid arthritis 121 | 121
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gamma-aminobutyric acid receptor-associated protein-like 3 GABARAPL3 Tdark Non-IDG -0.16137 0.12 0
Tyrosine-protein kinase Blk BLK Tchem Kinase -1.88753 81.6 418
Complement C1q tumor necrosis factor-related protein 6 C1QTNF6 Tbio Non-IDG -0.96811 13.3 219
Juxtaposed with another zinc finger protein 1 JAZF1 Tbio Non-IDG -1.61585 42.8 94
Butyrophilin-like protein 2 BTNL2 Tbio Non-IDG -2.57312 369.3 73
Interferon regulatory factor 5 IRF5 Tbio Transcription Factor -2.33923 241.0 400
Metal regulatory transcription factor 1 MTF1 Tbio Transcription Factor -1.98140 101.0 135
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.80099 639.3 247
Peptidyl-prolyl cis-trans isomerase-like 4 PPIL4 Tdark Enzyme -0.06695 1.03 143
AT-rich interactive domain-containing protein 5B ARID5B Tbio Transcription Factor -1.71561 54.6 97