Development Level

Tbio 126 | 11,651
Tdark 20 | 6,593
Tchem 12 | 1,388
Tclin 5 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 7 | 499
decreased total body fat amoun... 6 | 207
abnormal bone structure 5 | 187
abnormal embryo size 5 | 220
decreased circulating glucose ... 5 | 126
decreased erythrocyte cell num... 5 | 62
abnormal behavior 4 | 298
abnormal sleep behavior 4 | 70
decreased circulating serum al... 4 | 82
embryonic lethality prior to t... 4 | 278
enlarged heart 4 | 210
hypoactivity 4 | 132
increased bone mineral content 4 | 108
increased circulating alkaline... 4 | 122
increased lean body mass 4 | 172
increased mean corpuscular hem... 4 | 96
abnormal eye morphology 3 | 68
abnormal retina morphology 3 | 71
decreased bone mineral content 3 | 151
decreased vertical activity 3 | 208
embryonic growth retardation 3 | 106
increased circulating choleste... 3 | 66
male infertility 3 | 123
abnormal behavioral response t... 2 | 66
abnormal craniofacial morpholo... 2 | 33
abnormal heart morphology 2 | 162
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased circulating insulin ... 2 | 76
decreased grip strength 2 | 116
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 50
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
decreased red blood cell distr... 2 | 41
decreased startle reflex 2 | 75
decreased total retina thickne... 2 | 17
hyperactivity 2 | 148
increased body weight 2 | 25
increased circulating HDL chol... 2 | 80
increased circulating free fat... 2 | 20
increased circulating glucose ... 2 | 24
increased circulating iron lev... 2 | 30
increased circulating triglyce... 2 | 42
increased heart left ventricle... 2 | 4
increased heart weight 2 | 62
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
prenatal lethality prior to he... 2 | 87
abnormal body wall morphology 1 | 9
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
anophthalmia 1 | 33
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased body length 1 | 101
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
microphthalmia 1 | 26
prenatal lethality 1 | 28
shortened RR interval 1 | 17
small testis 1 | 58
small thymus 1 | 16
tremors 1 | 39

Disease

Carcinoma 111 | 11,493
osteosarcoma 102 | 7,950
ovarian cancer 93 | 8,520
glioblastoma 72 | 5,792
medulloblastoma, large-cell 71 | 6,241
atypical teratoid / rhabdoid tumor 59 | 5,112
ependymoma 58 | 4,679
psoriasis 58 | 6,694
lung cancer 54 | 4,740
group 3 medulloblastoma 47 | 4,104
adult high grade glioma 46 | 3,801
Breast cancer 41 | 3,578
Cancer 39 | 2,499
Astrocytoma, Pilocytic 38 | 3,081
malignant mesothelioma 38 | 3,232
Kidney cancer 36 | 2,613
invasive ductal carcinoma 35 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
oligodendroglioma 34 | 2,850
primitive neuroectodermal tumor 34 | 3,035
ulcerative colitis 31 | 1,819
Pick disease 29 | 1,894
astrocytic glioma 29 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
subependymal giant cell astrocytoma 28 | 2,287
non-small cell lung cancer 27 | 2,890
pancreatic cancer 27 | 2,398
Autosomal recessive predisposition 24 | 1,442
Rheumatoid arthritis 24 | 1,191
lung carcinoma 23 | 2,843
tuberculosis 23 | 2,010
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
cystic fibrosis 21 | 1,696
diabetes mellitus 20 | 1,728
ductal carcinoma in situ 19 | 1,745
mucosa-associated lymphoid tissue lymphoma 19 | 484
Schizophrenia 18 | 1,160
astrocytoma 18 | 1,146
group 4 medulloblastoma 18 | 1,855
lung adenocarcinoma 18 | 2,716
Anemia 16 | 365
pituitary cancer 16 | 1,972
dermatomyositis 15 | 966
juvenile dermatomyositis 15 | 1,187
spina bifida 15 | 1,074
interstitial cystitis 14 | 2,312
Obesity 13 | 678
Type 2 diabetes mellitus 13 | 272
breast carcinoma 13 | 1,638
colon cancer 13 | 1,478
esophageal adenocarcinoma 13 | 737
gastric carcinoma 13 | 807
Multiple myeloma 12 | 1,332
Neurodegenerative disease 12 | 414
Peripheral vascular disease 12 | 87
Short stature 12 | 531
acute myeloid leukemia 12 | 783
adrenocortical carcinoma 12 | 1,428
Bipolar Disorder 11 | 666
Intellectual disability 11 | 1,016
Kidney disease 11 | 430
Liver cancer 11 | 604
active Crohn's disease 11 | 922
acute quadriplegic myopathy 11 | 1,158
primary pancreatic ductal adenocarcinoma 11 | 1,109
Alzheimer's disease 10 | 658
Atopic dermatitis 10 | 952
Liver Cirrhosis, Experimental 10 | 769
Muscle hypotonia 10 | 571
Vascular disease 10 | 319
aldosterone-producing adenoma 10 | 665
pancreatic carcinoma 10 | 562
pediatric high grade glioma 10 | 1,064
Duchenne muscular dystrophy 9 | 601
Dull intelligence 9 | 645
Hemolytic anemia 9 | 77
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Osteoporosis 9 | 363
Poor school performance 9 | 645
Splenomegaly 9 | 190
Thalassemia 9 | 53
Waldenstrons macroglobulinemia 9 | 765
chronic rhinosinusitis 9 | 512
hereditary spastic paraplegia 9 | 318
non primary Sjogren syndrome sicca 9 | 891
Amyotrophic lateral sclerosis 8 | 451
Congenital hemolytic anemia 8 | 32
Crohn's disease 8 | 321
Diabetes Mellitus, Experimental 8 | 108
Melanoma 8 | 711
Skin cancer 8 | 469
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
cutaneous lupus erythematosus 8 | 1,057
nasopharyngeal carcinoma 8 | 1,058
Epilepsy 7 | 792
Hepatomegaly 7 | 285
hepatocellular carcinoma 7 | 547

Tissue

Blood and immune system 159 | 16,909
Female tissues 159 | 17,400
Endocrine System 158 | 18,159
Digestive Tract 157 | 17,369
Urinary Tract 154 | 16,678
Liver and Pancreas 153 | 16,750
Nervous System 153 | 16,725
Skin and soft tissues 153 | 17,230
Male tissues 152 | 17,142
Respiratory system 151 | 16,393
Cardiovascular System 143 | 15,192

Target Family

Non-IDG 96 | 12,091
Enzyme 36 | 4,145
Transcription Factor 11 | 1,400
Kinase 7 | 634
Transporter 6 | 473
Ion Channel 4 | 344
Epigenetic 1 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48

GWAS Trait

Reticulocyte fraction of red c... 163 | 163
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 AIMP2 Tbio Enzyme -1.35413 26.1 138
Probable E3 ubiquitin-protein ligase HERC1 HERC1 Tbio Enzyme -1.02371 5.75 39
Basic leucine zipper and W2 domain-containing protein 2 BZW2 Tbio Non-IDG -0.20261 1.21 83
E3 ubiquitin-protein ligase DZIP3 DZIP3 Tbio Enzyme -0.24304 1.68 116
ADP-ribosylation factor-like protein 15 ARL15 Tbio Enzyme -1.19117 15.8 82
Vacuolar protein sorting-associated protein 37D VPS37D Tdark Non-IDG 0.51 0.16 8
Probable palmitoyltransferase ZDHHC19 ZDHHC19 Tdark Enzyme 0.73 0.41 48
Spermine oxidase SMOX Tbio Enzyme -3.09513 1199.4 58
Contactin-5 CNTN5 Tbio Non-IDG -2.54880 296.6 100
Platelet glycoprotein VI GP6 Tbio Non-IDG -2.73714 584.5 201