Development Level

Tbio 118 | 11,651
Tdark 22 | 6,593
Tchem 12 | 1,388
Tclin 6 | 612

Collection

Kinase: IDG Consortium (Target... 3 | 125
RFA-RM-18-021 3 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 13 | 979
decreased total body fat amoun... 7 | 207
preweaning lethality, incomple... 7 | 499
abnormal embryo size 5 | 220
enlarged heart 5 | 210
increased bone mineral content 5 | 108
increased circulating alkaline... 5 | 122
abnormal bone structure 4 | 187
abnormal heart morphology 4 | 162
decreased circulating glucose ... 4 | 126
embryonic lethality prior to t... 4 | 278
abnormal behavior 3 | 298
abnormal eye morphology 3 | 68
decreased bone mineral content 3 | 151
decreased circulating insulin ... 3 | 76
decreased circulating serum al... 3 | 82
decreased erythrocyte cell num... 3 | 62
embryonic growth retardation 3 | 106
increased circulating choleste... 3 | 66
increased lean body mass 3 | 172
male infertility 3 | 123
abnormal cornea morphology 2 | 31
abnormal craniofacial morpholo... 2 | 33
abnormal sleep behavior 2 | 70
corneal opacity 2 | 32
decreased grip strength 2 | 116
decreased neutrophil cell numb... 2 | 42
decreased red blood cell distr... 2 | 41
decreased startle reflex 2 | 75
decreased total retina thickne... 2 | 17
decreased vertical activity 2 | 208
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating free fat... 2 | 20
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 96
increased mean platelet volume 2 | 45
prenatal lethality prior to he... 2 | 87
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal spinal cord morpholog... 1 | 9
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
anophthalmia 1 | 33
cataract 1 | 92
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased threshold for audito... 1 | 26
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
hyperactivity 1 | 148
increased body weight 1 | 25
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
shortened RR interval 1 | 17
small testis 1 | 58
small thymus 1 | 16
tremors 1 | 39
vertebral transformation 1 | 12

Disease

Carcinoma 104 | 11,493
osteosarcoma 95 | 7,950
ovarian cancer 83 | 8,520
medulloblastoma, large-cell 65 | 6,241
glioblastoma 63 | 5,792
psoriasis 59 | 6,694
ependymoma 54 | 4,679
atypical teratoid / rhabdoid tumor 53 | 5,112
lung cancer 50 | 4,740
group 3 medulloblastoma 44 | 4,104
adult high grade glioma 41 | 3,801
Cancer 37 | 2,499
Breast cancer 34 | 3,578
Kidney cancer 33 | 2,613
primitive neuroectodermal tumor 33 | 3,035
malignant mesothelioma 32 | 3,232
Astrocytoma, Pilocytic 31 | 3,081
ulcerative colitis 31 | 1,819
invasive ductal carcinoma 30 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
oligodendroglioma 29 | 2,850
Autosomal recessive predisposition 27 | 1,442
astrocytic glioma 26 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
non-small cell lung cancer 26 | 2,890
lung carcinoma 25 | 2,843
pancreatic cancer 25 | 2,398
Pick disease 24 | 1,894
tuberculosis 24 | 2,010
group 4 medulloblastoma 22 | 1,855
Rheumatoid arthritis 21 | 1,191
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
subependymal giant cell astrocytoma 20 | 2,287
diabetes mellitus 19 | 1,728
mucosa-associated lymphoid tissue lymphoma 18 | 484
Schizophrenia 17 | 1,160
cystic fibrosis 17 | 1,696
ductal carcinoma in situ 17 | 1,745
juvenile dermatomyositis 17 | 1,187
colon cancer 16 | 1,478
pituitary cancer 16 | 1,972
lung adenocarcinoma 15 | 2,716
Type 2 diabetes mellitus 14 | 272
astrocytoma 14 | 1,146
dermatomyositis 14 | 966
interstitial cystitis 14 | 2,312
spina bifida 14 | 1,074
Anemia 13 | 365
active Crohn's disease 13 | 922
Peripheral vascular disease 12 | 87
acute myeloid leukemia 12 | 783
esophageal adenocarcinoma 12 | 737
gastric carcinoma 12 | 807
Liver cancer 11 | 604
Short stature 11 | 531
Splenomegaly 11 | 190
breast carcinoma 11 | 1,638
Alzheimer's disease 10 | 658
Intellectual disability 10 | 1,016
Liver Cirrhosis, Experimental 10 | 769
Multiple myeloma 10 | 1,332
Muscle hypotonia 10 | 571
Osteoporosis 10 | 363
acute quadriplegic myopathy 10 | 1,158
adrenocortical carcinoma 10 | 1,428
cutaneous lupus erythematosus 10 | 1,057
pediatric high grade glioma 10 | 1,064
Atopic dermatitis 9 | 952
Bipolar Disorder 9 | 666
Congenital hemolytic anemia 9 | 32
Dull intelligence 9 | 645
Low intelligence 9 | 645
Melanoma 9 | 711
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Obesity 9 | 678
Poor school performance 9 | 645
aldosterone-producing adenoma 9 | 665
pancreatic carcinoma 9 | 562
primary pancreatic ductal adenocarcinoma 9 | 1,109
Coronary artery disease 8 | 268
Crohn's disease 8 | 321
Duchenne muscular dystrophy 8 | 601
Epilepsy 8 | 792
Hemolytic anemia 8 | 77
Hypertensive disease 8 | 292
Kidney disease 8 | 430
Neurodegenerative disease 8 | 414
Parkinson's disease 8 | 392
Prostatic Neoplasms 8 | 495
Vascular disease 8 | 319
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
nasopharyngeal carcinoma 8 | 1,058
non primary Sjogren syndrome sicca 8 | 891
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
chronic rhinosinusitis 7 | 512
primary Sjogren syndrome 7 | 735

Tissue

Blood and immune system 152 | 16,909
Female tissues 152 | 17,400
Endocrine System 151 | 18,159
Digestive Tract 150 | 17,369
Skin and soft tissues 149 | 17,230
Urinary Tract 148 | 16,678
Male tissues 147 | 17,142
Liver and Pancreas 146 | 16,750
Nervous System 146 | 16,725
Respiratory system 145 | 16,393
Cardiovascular System 136 | 15,192

Target Family

Non-IDG 92 | 12,091
Enzyme 34 | 4,145
Transcription Factor 10 | 1,400
Kinase 9 | 634
Transporter 5 | 473
Ion Channel 3 | 344
oGPCR 2 | 421
Epigenetic 1 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48

GWAS Trait

Reticulocyte count 158 | 158
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Basic leucine zipper and W2 domain-containing protein 2 BZW2 Tbio Non-IDG -0.20261 1.21 83
Ubiquitin carboxyl-terminal hydrolase 3 USP3 Tbio Enzyme -1.16770 14.5 246
ADP-ribosylation factor-like protein 15 ARL15 Tbio Enzyme -1.19117 15.8 82
Vacuolar protein sorting-associated protein 37D VPS37D Tdark Non-IDG 0.51 0.16 8
BAG family molecular chaperone regulator 5 BAG5 Tbio Non-IDG -1.25287 18.4 376
Spermine oxidase SMOX Tbio Enzyme -3.09513 1199.4 58
Contactin-5 CNTN5 Tbio Non-IDG -2.54880 296.6 100
Platelet glycoprotein VI GP6 Tbio Non-IDG -2.73714 584.5 201
HBS1-like protein HBS1L Tbio Non-IDG -2.55785 357.2 263
60S ribosomal protein L6 RPL6 Tbio Non-IDG -1.58528 37.8 68