Development Level

Tbio 49 | 11,445
Tdark 21 | 6,588
Tclin 7 | 613
Tchem 5 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
hypoactivity 2 | 132
increased prepulse inhibition 2 | 32
long tibia 2 | 25
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal nail morphology 1 | 8
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
decreased KLRG1+ CD8 alpha bet... 1 | 2
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased heart rate variabili... 1 | 13
decreased lactate dehydrogenas... 1 | 16
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
dilated heart left ventricle 1 | 11
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
head bobbing 1 | 5
hydrometra 1 | 53
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral content 1 | 108
increased cardiac stroke volum... 1 | 1
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased vertical activity 1 | 24
prenatal lethality prior to he... 1 | 87
small testis 1 | 58

Disease

Carcinoma 64 | 11,493
ovarian cancer 44 | 8,520
medulloblastoma, large-cell 40 | 6,241
osteosarcoma 40 | 7,950
psoriasis 32 | 6,694
atypical teratoid / rhabdoid tumor 31 | 5,112
glioblastoma 30 | 5,792
lung cancer 30 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
primitive neuroectodermal tumor 23 | 3,035
ependymoma 22 | 4,679
group 3 medulloblastoma 22 | 4,104
Kidney cancer 21 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
lung carcinoma 21 | 2,843
malignant mesothelioma 21 | 3,232
oligodendroglioma 21 | 2,850
lung adenocarcinoma 20 | 2,716
Breast cancer 19 | 3,578
adult high grade glioma 19 | 3,801
invasive ductal carcinoma 19 | 2,951
non-small cell lung cancer 19 | 2,890
Astrocytoma, Pilocytic 17 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
astrocytic glioma 16 | 2,597
pancreatic cancer 16 | 2,398
subependymal giant cell astrocytoma 16 | 2,287
pituitary cancer 15 | 1,972
Cancer 14 | 2,499
breast carcinoma 13 | 1,638
tuberculosis 13 | 2,010
group 4 medulloblastoma 12 | 1,855
Heart disease 11 | 306
Pick disease 11 | 1,894
Schizophrenia 11 | 1,160
adrenocortical carcinoma 11 | 1,428
interstitial cystitis 11 | 2,312
Liver cancer 10 | 604
diabetes mellitus 10 | 1,728
ductal carcinoma in situ 10 | 1,745
Autosomal recessive predisposition 9 | 1,442
Heart conduction disease 9 | 83
acute quadriplegic myopathy 9 | 1,158
astrocytoma 9 | 1,146
colon cancer 9 | 1,478
cystic fibrosis 9 | 1,696
dermatomyositis 9 | 966
nasopharyngeal carcinoma 9 | 1,058
primary pancreatic ductal adenocarcinoma 9 | 1,109
Down syndrome 7 | 499
Duchenne muscular dystrophy 7 | 601
Obesity 7 | 678
active Crohn's disease 7 | 922
gastric carcinoma 7 | 807
juvenile dermatomyositis 7 | 1,187
Heart failure 6 | 162
Type 2 diabetes mellitus 6 | 272
active ulcerative colitis 6 | 764
aldosterone-producing adenoma 6 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
hepatocellular carcinoma 6 | 547
interstitial lung disease 6 | 298
non-small cell lung carcinoma 6 | 317
pediatric high grade glioma 6 | 1,064
posterior fossa group A ependymoma 6 | 468
ulcerative colitis 6 | 1,819
Atrial Fibrillation 5 | 124
Cardiomyopathy 5 | 116
Hypertensive disease 5 | 292
Kidney disease 5 | 430
Parkinson's disease 5 | 392
Skin cancer 5 | 469
non primary Sjogren syndrome sicca 5 | 891
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Acquired metabolic disease 4 | 336
Alzheimer's disease 4 | 658
Atherosclerosis 4 | 291
Bipolar Disorder 4 | 666
Brugada Syndrome (disorder) 4 | 15
Brugada syndrome 4 | 29
Cardiac Arrhythmia 4 | 103
Cardiomyopathy, Dilated 4 | 83
Cardiovascular system disease 4 | 246
Congestive heart failure 4 | 113
Epilepsy 4 | 792
Hypertension 4 | 396
Large intestine cancer 4 | 126
Lipid metabolism disorder 4 | 114
Liver Cirrhosis, Experimental 4 | 769
Melanoma 4 | 711
Mood Disorders 4 | 184
Multiple myeloma 4 | 1,332
Neuropathy 4 | 261
Osteoporosis 4 | 363
Rheumatoid arthritis 4 | 1,191
Stomach Neoplasms 4 | 300
acute myeloid leukemia 4 | 783
posterior fossa group B ependymoma 4 | 416
primary Sjogren syndrome 4 | 735
progressive supranuclear palsy 4 | 676

Tissue

Endocrine System 79 | 18,159
Digestive Tract 77 | 17,369
Female tissues 77 | 17,400
Liver and Pancreas 77 | 16,750
Male tissues 77 | 17,142
Cardiovascular System 76 | 15,192
Nervous System 76 | 16,725
Respiratory system 76 | 16,393
Skin and soft tissues 76 | 17,230
Urinary Tract 76 | 16,678
Blood and immune system 75 | 16,909

Target Family

Non-IDG 49 | 12,091
Enzyme 12 | 4,145
Transcription Factor 8 | 1,400
Ion Channel 5 | 344
Kinase 4 | 634
GPCR 2 | 408
Transporter 2 | 473

GWAS Trait

Resting heart rate 82 | 82
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.17690 1469.3 126
Galactose-3-O-sulfotransferase 4 GAL3ST4 Tdark Enzyme -0.48192 3.06 142
CUB and sushi domain-containing protein 1 CSMD1 Tbio Non-IDG -1.68684 47.7 0
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Tclin Ion Channel -2.48671 270.6 121
Uncharacterized protein C19orf47 C19orf47 Tdark Non-IDG 0.00000 79
Peripheral myelin protein 22 PMP22 Tbio Non-IDG -2.50612 344.4 262
Uncharacterized aarF domain-containing protein kinase 1 ADCK1 Tdark Kinase -0.04093 1.09 142
FERM domain-containing protein 4B FRMD4B Tdark Non-IDG -0.63178 4.93 32
Coiled-coil domain-containing protein 141 CCDC141 Tbio Non-IDG -0.66635 5.13 88
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45