Development Level

Tbio 8 | 11,445
Tchem 5 | 1,598
Tdark 5 | 6,588
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

decreased circulating alkaline... 3 | 46
abnormal bone structure 2 | 187
abnormal locomotor behavior 2 | 24
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased pulmonary respirator... 2 | 5
decreased total body fat amoun... 2 | 207
enlarged stomach 2 | 2
impaired glucose tolerance 2 | 75
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased lean body mass 2 | 172
increased red blood cell distr... 2 | 34
increased total body fat amoun... 2 | 134
short tibia 2 | 97
small thymus 2 | 16
tremors 2 | 39
abnormal embryo size 1 | 220
decreased heart rate 1 | 18
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
preweaning lethality, complete... 1 | 979
prolonged RR interval 1 | 8

Disease

Carcinoma 17 | 11,493
glioblastoma 10 | 5,792
medulloblastoma, large-cell 10 | 6,241
ovarian cancer 10 | 8,520
atypical teratoid / rhabdoid tumor 9 | 5,112
ependymoma 9 | 4,679
Kidney cancer 8 | 2,613
adult high grade glioma 8 | 3,801
primitive neuroectodermal tumor 8 | 3,035
psoriasis 8 | 6,694
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
osteosarcoma 7 | 7,950
lung cancer 6 | 4,740
astrocytic glioma 5 | 2,597
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
Epilepsy 4 | 792
Liver cancer 4 | 604
Rheumatoid arthritis 4 | 1,191
group 3 medulloblastoma 4 | 4,104
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Autism spectrum disorder 3 | 101
Autistic Disorder 3 | 364
Bipolar Disorder 3 | 666
Intellectual disability 3 | 1,016
Nicotine dependence 3 | 54
Obesity 3 | 678
Schizophrenia 3 | 1,160
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
nasopharyngeal carcinoma 3 | 1,058
pancreatic cancer 3 | 2,398
ulcerative colitis 3 | 1,819
Asperger syndrome 2 | 37
Autosomal recessive predisposition 2 | 1,442
Dental caries 2 | 164
Depressive disorder 2 | 409
Endometrial cancer 2 | 311
Gastroesophageal reflux disease 2 | 110
Gilles de la Tourette syndrome 2 | 47
Heartburn 2 | 78
Large intestine cancer 2 | 126
Melanoma 2 | 711
Mental Depression 2 | 333
Motor neuron disease 2 | 49
Muscle hypotonia 2 | 571
Pick disease 2 | 1,894
Pitt-Hopkins syndrome 2 | 20
Pitt-Hopkins-Like Syndrome 2 2 | 2
Seizures 2 | 596
Skin cancer 2 | 469
Systemic lupus erythematosus 2 | 194
Vascular disease 2 | 319
active ulcerative colitis 2 | 764
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
inflammatory breast cancer 2 | 286
mucosa-associated lymphoid tissue lymphoma 2 | 484
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
Abnormal urinary amino-acid findings 1 | 38
Abnormalities, Multiple 1 | 13
Aminoaciduria 1 | 38
Argininosuccinic aciduria 1 | 17
Autism Spectrum Disorders 1 | 75
CHROMOSOME 2p16.3 DELETION SYNDROME 1 | 1
Citrullinemia 1 | 14
Conduct disorder 1 | 33
Cortical Dysplasia-Focal Epilepsy Syndrome 1 | 2
Diabetic Nephropathy 1 | 34
Epileptic encephalopathy 1 | 26
Hyperargininemia 1 | 8
Hypertensive disorder 1 | 56
Infiltrate of lung 1 | 17
Language Development Disorders 1 | 11
Lytic lesion 1 | 32
Precancerous Conditions 1 | 80
Protrusion of tongue 1 | 11
Pulmonary Fibrosis 1 | 106
Pulmonary Stenosis 1 | 45
Rotting teeth 1 | 73
Silver-Russell syndrome 1 | 39
Skin Ulcer 1 | 48
Staphyloenterotoxemia 1 | 18
Systemic scleroderma 1 | 60
Toxic shock syndrome 1 | 28
Ventricular Dysfunction, Left 1 | 22
hypopigmented skin patch 1 | 59

Tissue

Endocrine System 18 | 18,159
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 7 | 12,091
Enzyme 6 | 4,145
GPCR 2 | 408
Transporter 2 | 473
Ion Channel 1 | 344
Kinase 1 | 634

GWAS Trait

Response to zileuton treatment... 19 | 19
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Cationic amino acid transporter 2 SLC7A2 Tbio Transporter -1.55868 37.6 57
Uncharacterized protein C4orf50 C4orf50 Tdark Non-IDG 0.00000 5
Inactive serine protease 35 PRSS35 Tdark Enzyme -0.42935 3.31 54
Protein sidekick-2 SDK2 Tdark Non-IDG -0.42720 2.61 17
Carbamoyl-phosphate synthase [ammonia], mitochondrial CPS1 Tclin Enzyme -2.28267 188.9 238
Neurexin-1-beta NRXN1 Tbio Non-IDG -1.88807 125.1 174
Bifunctional epoxide hydrolase 2 EPHX2 Tchem Enzyme -2.57266 349.1 245
Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 Tchem Ion Channel -1.31722 18.3 117
Adhesion G protein-coupled receptor B3 ADGRB3 Tbio GPCR -0.99526 10.1 137