Development Level

Tbio 12 | 11,651
Tdark 4 | 6,593

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

abnormal behavior 1 | 298
abnormal locomotor activation 1 | 16
abnormal locomotor behavior 1 | 24
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
female infertility 1 | 60
hyperactivity 1 | 148
increased aggression 1 | 4
increased heart weight 1 | 62
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 14 | 11,493
medulloblastoma, large-cell 10 | 6,241
ovarian cancer 9 | 8,520
Kidney cancer 8 | 2,613
atypical teratoid / rhabdoid tumor 8 | 5,112
ependymoma 8 | 4,679
adult high grade glioma 7 | 3,801
glioblastoma 7 | 5,792
Astrocytoma, Pilocytic 6 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
malignant mesothelioma 6 | 3,232
pituitary cancer 6 | 1,972
Breast cancer 5 | 3,578
Pick disease 5 | 1,894
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
psoriasis 5 | 6,694
Melanoma 4 | 711
Skin cancer 4 | 469
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Schizophrenia 3 | 1,160
colon cancer 3 | 1,478
interstitial cystitis 3 | 2,312
lung carcinoma 3 | 2,843
tuberculosis 3 | 2,010
Alzheimer's disease 2 | 658
Amphetamine-Related Disorders 2 | 74
Atopic dermatitis 2 | 952
Depressive disorder 2 | 409
Endometrial cancer 2 | 311
Mental Depression 2 | 333
Osteoporosis 2 | 363
acute quadriplegic myopathy 2 | 1,158
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,855
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
ulcerative colitis 2 | 1,819
Abnormality of the cranial nerves 1 | 7
Adult onset 1 | 82
Autism Spectrum Disorders 1 | 75
Autism spectrum disorder 1 | 101
Autistic Disorder 1 | 364
Breast Neoplasms 1 | 445
Cannabis dependence 1 | 23
Carcinoma, Non-Small-Cell Lung 1 | 107
Cranial nerve abnormality 1 | 7
Creutzfeldt-Jakob disease 1 | 21
DOID:3363 1 | 3
Delusional disorder 1 | 13
Dentin sensitivity 1 | 14
Diastrophic dysplasia 1 | 21
Essential Hypertension 1 | 94
Gaucher disease type 1 1 | 180
Heart conduction disease 1 | 83
Heart disease 1 | 306
Heart failure 1 | 162
Hemolytic anemia 1 | 77
Hirschsprung Disease 1 | 31
Hirschsprung's disease 1 | 46
Hyperparathyroidism 1 | 48
Intestinal Obstruction 1 | 31
Learning disability 1 | 17
Lipid metabolism disorder 1 | 114
Liver Cirrhosis, Experimental 1 | 769
Liver cancer 1 | 604
Lung Neoplasms 1 | 232
Mammary Neoplasms 1 | 425
Mesothelioma, Malignant 1 | 105
Movement Disorders 1 | 55
Myocardial Infarction 1 | 151
Neoplasm Invasiveness 1 | 161
Neuropathy 1 | 261
Parkinson's disease 1 | 392
Peripheral vascular disease 1 | 87
Pruritus 1 | 58
facioscapulohumeral dystrophy 1 | 288
head and neck cancer 1 | 271
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
interstitial lung disease 1 | 298
limb girdle muscular dystrophy 2B 1 | 40
non-small cell lung carcinoma 1 | 317
posterior fossa group A ependymoma 1 | 468
sarcoidosis 1 | 370
tuberculosis and treatment for 6 months 1 | 409
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Male tissues 15 | 17,142
Endocrine System 14 | 18,159
Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Nervous System 12 | 16,725
Cardiovascular System 11 | 15,192

Target Family

Non-IDG 8 | 12,091
Enzyme 3 | 4,145
oGPCR 2 | 421
GPCR 1 | 408
Ion Channel 1 | 344
Transporter 1 | 473

GWAS Trait

Response to serotonin reuptake... 16 | 16
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphatase and actin regulator 1 PHACTR1 Tbio Enzyme -1.79171 63.2 41
Stathmin-2 STMN2 Tbio Non-IDG -1.97011 93.3 326
Oncostatin-M-specific receptor subunit beta OSMR Tbio Non-IDG -2.26877 178.8 258
Adenylyl cyclase-associated protein 2 CAP2 Tbio Enzyme -0.39794 2.39 125
RalBP1-associated Eps domain-containing protein 1 REPS1 Tbio Non-IDG -0.88393 7.90 53
Pro-neuregulin-1, membrane-bound isoform NRG1 Tbio Non-IDG -2.93105 922.4 560
Olfactory receptor 11L1 OR11L1 Tdark oGPCR 0.22 0.59 85
Olfactory receptor 52I2 OR52I2 Tdark oGPCR 0.00000 69
E3 ubiquitin-protein ligase TRIM58 TRIM58 Tbio Enzyme -1.22144 16.5 88
CUB and sushi domain-containing protein 2 CSMD2 Tdark Non-IDG -0.52710 3.50 43