Development Level

Tbio 8 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

embryonic lethality prior to o... 1 | 239
long tibia 1 | 25
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
short tibia 1 | 97

Disease

adult high grade glioma 6 | 3,801
Astrocytoma, Pilocytic 5 | 3,081
Carcinoma 5 | 11,493
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
medulloblastoma, large-cell 5 | 6,241
atypical teratoid / rhabdoid tumor 4 | 5,112
oligodendroglioma 4 | 2,850
Kidney cancer 3 | 2,613
Pick disease 3 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
subependymal giant cell astrocytoma 3 | 2,287
Colorectal Neoplasms 2 | 243
Liver cancer 2 | 604
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
hereditary spastic paraplegia 2 | 318
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
psoriasis 2 | 6,694
Abnormal cortical bone morphology 1 | 22
Abnormal vision 1 | 52
Abnormality of epiphysis morphology 1 | 39
Abnormality of metabolism/homeostasis 1 | 134
Abnormality of the hip bone 1 | 16
Abnormality of the palate 1 | 17
Acro-Osteolysis 1 | 12
Anhidrosis 1 | 23
Ankle clonus 1 | 6
Autonomic neuropathy 1 | 22
Axonal neuropathy 1 | 27
Botulism 1 | 24
Brainstem atrophy 1 | 2
Cerebellar Dysmetria 1 | 56
Cherubism 1 | 13
Congenital myasthenic syndrome 5 1 | 11
Decreased bone mineral density Z score 1 | 31
Decreased nerve conduction velocity 1 | 35
Decreased projection of midface 1 | 105
Decreased sensory nerve conduction velocities (NCV) 1 | 8
Dilated ventricles (finding) 1 | 121
Disorder of eye 1 | 27
Drowsiness 1 | 7
Dystrophic fingernails 1 | 18
Dystrophic toenail changes 1 | 12
Edema of eyelid 1 | 10
Edema of lower extremity 1 | 3
Eye Abnormalities 1 | 35
Familial hemophagocytic lymphohistiocytosis 4 1 | 2
Febrile Convulsions 1 | 14
Gaucher disease type 3 1 | 67
Goldberg-Shprintzen syndrome 1 | 6
Hemolytic-Uremic Syndrome 1 | 30
Hereditary spastic paraplegia 15 1 | 6
Hyperhidrosis disorder 1 | 81
Hypogeusia 1 | 5
Hypotrophic malar bone 1 | 129
Hypotrophic midface 1 | 105
Hypsarrhythmia 1 | 25
Increased sweating 1 | 81
Infectious mononucleosis 1 | 14
Kidney Diseases 1 | 114
Large auricle 1 | 87
Large dysplastic ears 1 | 87
Large pinnae 1 | 87
Large prominent ears 1 | 87
Large protruding ears 1 | 87
Large, floppy ears 1 | 87
Leg edema 1 | 3
Lordosis 1 | 54
Lower limb spasticity 1 | 10
Malar flattening 1 | 129
Malformed pinnae 1 | 37
Midface retrusion 1 | 105
Nasopharynx carcinoma 1 | 18
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Open mouth 1 | 45
Paronychia Inflammation 1 | 9
Peripheral Neuropathy 1 | 134
Peripheral axonal neuropathy 1 | 18
Peripheral edema 1 | 5
Porencephaly 1 | 20
Recurrent respiratory infections 1 | 141
Seizures, Febrile 1 | 7
Sjogren's syndrome 1 | 26
Small midface 1 | 105
Spastic Ataxia 1 | 18
Spastic gait 1 | 23
Sphincter disturbances 1 | 16
Sweating 1 | 81
Tapering fingers (finding) 1 | 25
Tetanus 1 | 68
Weakness of lower limb 1 | 27
inflammatory breast cancer 1 | 286

Tissue

Digestive Tract 10 | 17,369
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 2 | 4,145

GWAS Trait

Response to metformin (IC50) 10 | 10
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF1A KIF1A Tbio Non-IDG -2.11552 130.9 37
Threonine synthase-like 2 THNSL2 Tbio Enzyme -1.56098 37.5 97
Synaptic vesicle glycoprotein 2B SV2B Tbio Non-IDG -1.20339 12.5 100
Aquaporin-12A AQP12A Tbio Non-IDG -0.93600 10.8 63
SH3 domain and tetratricopeptide repeat-containing protein 1 SH3TC1 Tdark Non-IDG 0.48 0.08 77
Syntaxin-4 STX4 Tbio Non-IDG -1.95295 84.2 207
Syntaxin-1B STX1B Tbio Non-IDG -1.76579 55.3 27
Serine-rich coiled-coil domain-containing protein 1 CCSER1 Tdark Non-IDG -0.47412 3.73 64
DNA polymerase delta subunit 3 POLD3 Tbio Enzyme -1.31704 20.0 144
Golgi integral membrane protein 4 GOLIM4 Tbio Non-IDG -1.44360 27.2 86