Development Level

Tbio 7 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal embryo size 2 | 220
preweaning lethality, complete... 2 | 979
abnormal body wall morphology 1 | 9
abnormal facial morphology 1 | 17
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal neural tube closure 1 | 46
abnormal tail morphology 1 | 25
cleft palate 1 | 8
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased eosinophil cell numb... 1 | 24
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hemorrhage 1 | 23

Disease

ovarian cancer 9 | 8,520
Carcinoma 8 | 11,493
osteosarcoma 5 | 7,950
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
psoriasis 4 | 6,694
glioblastoma 3 | 5,792
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
pituitary cancer 3 | 1,972
posterior fossa group B ependymoma 3 | 416
Acquired metabolic disease 2 | 336
Amyotrophic lateral sclerosis 2 | 451
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Kidney cancer 2 | 2,613
Melanoma 2 | 711
Obesity 2 | 678
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
ulcerative colitis 2 | 1,819
Acrodermatitis enteropathica 1 | 18
Alcohol withdrawal syndrome 1 | 20
Allergic hypersensitivity disease 1 | 126
Alzheimer Disease 1 | 83
Alzheimer's disease 1 | 658
Anemia 1 | 365
Astrocytoma, Pilocytic 1 | 3,081
Atopic dermatitis 1 | 952
Autism spectrum disorder 1 | 101
Autistic Disorder 1 | 364
Bone Diseases, Developmental 1 | 27
Brain cancer 1 | 30
Calcinosis 1 | 70
Cerebrovascular disease 1 | 238
Clubfoot 1 | 39
Complement deficiency disease 1 | 6
Cowpox 1 | 16
Diabetes Mellitus, Type 2 1 | 142
Dyspepsia 1 | 33
Endometriosis 1 | 540
Heart Septal Defects, Ventricular 1 | 6
Heart Valve Diseases 1 | 25
Heart valve disease 1 | 39
Ileocolitis 1 | 5
Jaw Abnormalities 1 | 5
Kidney Diseases 1 | 114
Liver neoplasms 1 | 130
Lower Extremity Deformities, Congenital 1 | 2
Lung diseases 1 | 50
Malignant glioma 1 | 26
Mastocytosis 1 | 27
Meningitis 1 | 67
Monkeypox 1 | 12
Motion sickness 1 | 21
Multiple Sclerosis 1 | 540
Pain agnosia 1 | 104
Pick disease 1 | 1,894
Polycystic ovary syndrome 1 | 360
Precancerous Conditions 1 | 80
Respiratory Hypersensitivity 1 | 19
Schizophrenia 1 | 1,160
Schizophrenia, Catatonic 1 | 4
Secretory diarrhea 1 | 10
Skin cancer 1 | 469
Susceptibility to viral and mycobacterial infections 1 | 11
Systemic lupus erythematosus 1 | 194
Tracheoesophageal Fistula 1 | 36
Urticaria 1 | 67
VACTERL association 1 | 26
Ventricular Septal Defects 1 | 119
astrocytoma 1 | 1,146
atypical teratoid/rhabdoid tumor 1 | 357
breast carcinoma 1 | 1,638
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
cystic fibrosis and chronic rhinosinusitis 1 | 214
dermatomyositis 1 | 966
gastric carcinoma 1 | 807
glioblastoma multiforme 1 | 142
head and neck cancer 1 | 271
nasopharyngeal carcinoma 1 | 1,058
non-small cell lung cancer 1 | 2,890
non-small cell lung carcinoma 1 | 317
oligodendroglioma 1 | 2,850
pancreatic cancer 1 | 2,398
severe Alzheimer's disease 1 | 47
sonic hedgehog group medulloblastoma 1 | 467

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 4 | 12,091
Enzyme 3 | 4,145
Epigenetic 1 | 242
Transcription Factor 1 | 1,400
Transporter 1 | 473

GWAS Trait

Response to fenofibrate (adipo... 10 | 10
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Signal peptide, CUB and EGF-like domain-containing protein 1 SCUBE1 Tbio Non-IDG -1.36066 28.2 70
Transmembrane protein 18 TMEM18 Tbio Non-IDG -1.42979 26.0 80
Lysine-specific demethylase 4C KDM4C Tchem Epigenetic -1.64807 46.2 208
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 ENPP3 Tbio Enzyme -2.63069 396.7 315
Proprotein convertase subtilisin/kexin type 5 PCSK5 Tchem Enzyme -2.88342 751.2 143
Complement component C6 C6 Tbio Non-IDG -1.55226 36.1 153
SH3 and multiple ankyrin repeat domains protein 2 SHANK2 Tbio Non-IDG -1.83848 71.4 220
Zinc transporter 4 SLC30A4 Tbio Transporter -1.52046 33.6 42
Zinc finger protein 664 ZNF664 Tdark Transcription Factor -0.47442 2.93 33
ATP-dependent RNA helicase DDX54 DDX54 Tbio Enzyme -0.86363 8.48 133