Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal cornea morphology 1 | 31
abnormal eye pigmentation 1 | 3
absent pinna reflex 1 | 23
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased lean body mass 1 | 135
female infertility 1 | 60
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123

Disease

glioblastoma 6 | 5,792
Carcinoma 5 | 11,493
group 3 medulloblastoma 5 | 4,104
medulloblastoma, large-cell 5 | 6,241
ovarian cancer 5 | 8,520
Astrocytoma, Pilocytic 4 | 3,081
atypical teratoid / rhabdoid tumor 4 | 5,112
oligodendroglioma 4 | 2,850
osteosarcoma 4 | 7,950
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
ependymoma 3 | 4,679
interstitial cystitis 3 | 2,312
lung cancer 3 | 4,740
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Breast cancer 2 | 3,578
Duchenne muscular dystrophy 2 | 601
Intellectual disability 2 | 1,016
Microcephaly 1, Primary, Autosomal Recessive 2 | 2
Rheumatoid arthritis 2 | 1,191
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
non-small cell lung cancer 2 | 2,890
pituitary cancer 2 | 1,972
Abortion, Spontaneous 1 | 109
Aggressive behavior 1 | 75
Aggressive reaction 1 | 75
Agranulocytosis 1 | 6
Amyloidosis 1 | 67
Amyotrophic lateral sclerosis 1 | 451
Atypical absence seizure 1 | 5
Autism Spectrum Disorders 1 | 75
Autistic behavior 1 | 20
Brain Ischemia 1 | 110
Brainstem abnormalities 1 | 7
Cloudy cornea 1 | 33
Corneal Scar 1 | 7
Corneal Ulcer 1 | 21
Corneal dystrophy 1 | 24
Corneal edema 1 | 14
Corneal erosion 1 | 16
Corneal stromal opacities 1 | 33
Decreased visual acuity, progressive 1 | 36
Diabetic Nephropathies 1 | 37
Diabetic Nephropathy 1 | 34
Diabetic retinopathy 1 | 56
EEG with focal sharp slow waves 1 | 5
Encephalopathies 1 | 43
Epilepsy 1 | 792
Epileptic drop attack 1 | 11
Epithelial corneal erosions 1 | 12
Familial hemophagocytic lymphohistiocytosis 1 1 | 11
Familial hemophagocytic lymphohistiocytosis 2 1 | 15
Hemangiosarcoma 1 | 18
Hemolytic anemia 1 | 77
Hyperactive behavior 1 | 91
Hypertonic seizures 1 | 8
Hypotonic seizures 1 | 11
Keratoconus 1 | 113
Lennox-Gastaut syndrome 1 | 34
Low Vision 1 | 174
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 1 | 16
Malaria 1 | 160
Mental deterioration 1 | 32
Microcephalic osteodysplastic primordial dwarfism type II 1 | 13
Microcephaly 1 | 166
Motor neuron disease 1 | 49
Myoclonus 1 | 74
Neurodegenerative disease 1 | 414
Osteoporosis 1 | 363
Personality Disorders 1 | 7
Photodysphoria 1 | 121
Photophobia 1 | 121
Physical aggression 1 | 76
Polycystic ovary syndrome 1 | 360
Progressive visual loss 1 | 36
Recurrent erosion of cornea 1 | 12
Reduced visual acuity 1 | 63
Respiratory Failure 1 | 104
Retinopathy of prematurity 1 | 22
Seckel syndrome 1 | 34
Sepsis 1 | 24
Spontaneous abortion 1 | 113
Strabismus 1 | 270
Substance-Related Disorders 1 | 115
Tangier disease 1 | 10
Tonic - clonic seizures 1 | 44
Visual Impairment 1 | 174
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
atypical teratoid/rhabdoid tumor 1 | 357
inflammatory breast cancer 1 | 286
interstitial lung disease 1 | 298
medulloblastoma 1 | 720
pediatric high grade glioma 1 | 1,064
tuberculosis 1 | 2,010
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 7 | 12,091
Kinase 1 | 634

GWAS Trait

Response to cytidine analogues... 8 | 8
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Docking protein 6 DOK6 Tbio Non-IDG -0.45629 3.37 117
Transforming growth factor-beta-induced protein ig-h3 TGFBI Tbio Non-IDG -2.63615 441.5 287
Microcephalin MCPH1 Tbio Non-IDG -1.96863 109.3 260
KICSTOR complex protein C12orf66 C12orf66 Tbio Non-IDG 0.65 0.20 7
Protein NipSnap homolog 3A NIPSNAP3A Tdark Non-IDG -0.30963 2.06 102
Mitogen-activated protein kinase 10 MAPK10 Tchem Kinase -2.29568 193.3 384
Angiopoietin-2 ANGPT2 Tbio Non-IDG -2.81963 734.5 455
Dedicator of cytokinesis protein 1 DOCK1 Tbio Non-IDG -1.90662 82.3 188