Development Level

Tbio 6 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

decreased bone mineral density 2 | 126
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
decreased NK cell number 1 | 2
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating total pr... 1 | 49
decreased mature B cell number 1 | 7
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72

Disease

Carcinoma 8 | 11,493
ovarian cancer 8 | 8,520
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
ependymoma 6 | 4,679
osteosarcoma 6 | 7,950
Astrocytoma, Pilocytic 5 | 3,081
adult high grade glioma 5 | 3,801
psoriasis 5 | 6,694
atypical teratoid / rhabdoid tumor 4 | 5,112
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
Bipolar Disorder 3 | 666
Breast cancer 3 | 3,578
Obesity 3 | 678
Schizophrenia 3 | 1,160
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
Cancer 2 | 2,499
Duchenne muscular dystrophy 2 | 601
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
cystic fibrosis 2 | 1,696
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
mucosa-associated lymphoid tissue lymphoma 2 | 484
nephrosclerosis 2 | 333
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis 2 | 2,010
Acquired flat foot 1 | 72
Alopecia areata 1 | 41
Anxiety 1 | 136
Anxiety disease 1 | 113
Aortic Valve Insufficiency 1 | 40
Aortic aneurysm 1 | 38
Arachnodactyly 1 | 49
Arterial tortuosity 1 | 5
Arterial tortuosity, generalized 1 | 2
Atypical scarring of skin 1 | 62
Blue sclera 1 | 32
Bone neoplasms 1 | 8
Brachydactyly 1 | 156
COPD 1 | 118
Cardiomegaly 1 | 116
Celiac disease 1 | 116
Cleft palate with cleft lip 1 | 23
Congenital Camptodactyly 1 | 40
Contracture of joint of hand 1 | 30
Coughing 1 | 25
Death in early adulthood 1 | 24
Dental caries 1 | 164
Diabetic Nephropathies 1 | 37
Diabetic Nephropathy 1 | 34
Eaton-Lambert syndrome 1 | 40
Esophageal Neoplasms 1 | 69
Exotropia 1 | 35
Fatty liver disease 1 | 103
Fetal alcohol spectrum disorder 1 | 7
Flatfoot 1 | 73
Fractures, Bone 1 | 13
Gastrointestinal Stromal Tumors 1 | 48
Hereditary nonpolyposis colorectal carcinoma 1 | 18
Hypotrophic malar bone 1 | 129
Intermittent migraine headaches 1 | 68
Irritation - emotion 1 | 68
Joint laxity 1 | 54
Linear atrophy 1 | 15
Lynch syndrome 1 | 35
Malar flattening 1 | 129
Malignant Squamous Cell Neoplasm 1 | 17
Malignant tumor of colon 1 | 19
Migraine Disorders 1 | 76
Mucoepidermoid carcinoma 1 | 26
Occult macular dystrophy 1 | 7
Oral cleft 1 | 18
Papillary carcinoma 1 | 6
Pleomorphic adenoma 1 | 18
Pulmonary artery aneurysm 1 | 2
Skull malformation 1 | 38
Squamous cell carcinoma 1 | 129
Sternal anomalies 1 | 19
Tall stature 1 | 34
Thrombophlebitis 1 | 19
Thyroid cancer 1 | 36
inflammatory breast cancer 1 | 286

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Cardiovascular System 9 | 15,192
Respiratory system 9 | 16,393

Target Family

Non-IDG 4 | 12,091
Enzyme 3 | 4,145
Kinase 2 | 634
Ion Channel 1 | 344

GWAS Trait

Response to chemotherapy in br... 10 | 10
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial peptide methionine sulfoxide reductase MSRA Tbio Enzyme -1.92325 88.1 167
Tyrosine-protein phosphatase non-receptor type 4 PTPN4 Tbio Enzyme -1.90943 80.6 92
TGF-beta receptor type-2 TGFBR2 Tchem Kinase -2.84120 665.1 548
Beta-parvin PARVB Tbio Non-IDG -1.26717 17.4 137
GRAM domain-containing protein 1B GRAMD1B Tdark Non-IDG -0.37654 2.90 39
Synaptic vesicle glycoprotein 2C SV2C Tbio Non-IDG -1.38055 21.0 85
Mastermind-like protein 2 MAML2 Tbio Non-IDG -1.82854 72.4 136
Potassium voltage-gated channel subfamily S member 3 KCNS3 Tclin Ion Channel -1.07346 11.6 73
tRNA-specific adenosine deaminase 2 ADAT2 Tbio Enzyme -1.50829 23.9 51
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 PFKFB3 Tchem Kinase -2.28070 206.0 228