Development Level

Tbio 8 | 11,445
Tdark 4 | 6,588

IMPC Phenotype

abnormal epididymis morphology 1 | 42
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
female infertility 1 | 60
increased body weight 1 | 25
increased circulating triglyce... 1 | 42
increased or absent threshold ... 1 | 101
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
small testis 1 | 58

Disease

Mental Depression 10 | 333
Carcinoma 8 | 11,493
ovarian cancer 8 | 8,520
osteosarcoma 6 | 7,950
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
psoriasis 5 | 6,694
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
Kidney cancer 3 | 2,613
Liver cancer 3 | 604
colon cancer 3 | 1,478
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Alzheimer's disease 2 | 658
Atopic dermatitis 2 | 952
Breast cancer 2 | 3,578
Lymphoid leukemia 2 | 160
Melanoma 2 | 711
Schizophrenia 2 | 1,160
Skin cancer 2 | 469
active ulcerative colitis 2 | 764
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
chronic lymphosyte leukemia 2 | 204
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
sarcoidosis 2 | 370
subependymal giant cell astrocytoma 2 | 2,287
Acquired metabolic disease 1 | 336
Adenoid Cystic Carcinoma 1 | 99
Adult onset 1 | 82
Amyotrophic lateral sclerosis 1 | 451
Carcinoma, Adenoid Cystic 1 | 99
Cardiac Arrhythmia 1 | 103
Cardiac conduction abnormalities 1 | 78
Cardiomegaly 1 | 116
Cardiomyopathies 1 | 110
Cardiomyopathy 1 | 116
Cataract 8 multiple types 1 | 33
Childhood onset 1 | 38
Conduction disorder of the heart 1 | 79
Congestive heart failure 1 | 113
Contracture 1 | 96
Contracture of joint 1 | 93
Decreased tendon reflex 1 | 122
Difficulty walking 1 | 28
Difficulty walking up stairs 1 | 12
Dilated cardiomyopathy 1 | 56
Disease Models, Animal 1 | 155
EKG abnormalities 1 | 78
Electrocardiogram abnormal 1 | 81
Electrocardiogram change 1 | 78
Elevated hepatic transaminases 1 | 81
Fatigue 1 | 182
Flexion contracture 1 | 93
Flexion contractures of joints 1 | 93
Gastrointestinal Stromal Tumors 1 | 48
Gowers sign 1 | 24
Gowers sign present 1 | 24
Heart failure 1 | 162
Hepatic enzyme increased 1 | 81
Hypoventilation 1 | 8
Liver Cirrhosis, Experimental 1 | 769
Liver Dysfunction 1 | 99
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
MAJOR AFFECTIVE DISORDER 2 1 | 22
Muscle Weakness 1 | 170
Muscle biopsy shows dystrophic changes 1 | 39
Muscular dystrophy 1 | 75
Myocardial Infarction 1 | 151
Necrosis 1 | 53
Neoplasm Metastasis 1 | 168
Neuropathy 1 | 261
Oculocerebrorenal syndrome 1 | 29
Pervasive developmental disorder 1 | 9
Respiratory Depression 1 | 10
Respiratory Failure 1 | 104
Subclinical abnormal liver function tests 1 | 81
Systemic lupus erythematosus 1 | 194
Transaminases increased 1 | 81
Urine color abnormal 1 | 6
Waddling gait 1 | 34
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
hereditary spastic paraplegia 1 | 318
non-small cell lung carcinoma 1 | 317

Tissue

Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Blood and immune system 11 | 16,909
Liver and Pancreas 11 | 16,750
Urinary Tract 11 | 16,678
Cardiovascular System 10 | 15,192

Target Family

Enzyme 6 | 4,145
Non-IDG 5 | 12,091
Transcription Factor 1 | 1,400

GWAS Trait

Response to anti-depressant tr... 12 | 12
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 MAGI2 Tbio Enzyme -1.54170 33.0 178
N-terminal Xaa-Pro-Lys N-methyltransferase 1 NTMT1 Tbio Enzyme -1.08039 12.3 89
Probable palmitoyltransferase ZDHHC14 ZDHHC14 Tdark Enzyme -0.80618 5.28 33
WD repeat- and FYVE domain-containing protein 4 WDFY4 Tdark Non-IDG -0.35780 2.98 34
Forkhead box protein D2 FOXD2 Tdark Transcription Factor -0.55024 3.73 91
Cytosolic carboxypeptidase 4 AGBL1 Tbio Enzyme -0.95223 8.42 34
Phosphatidylinositide phosphatase SAC1 SACM1L Tbio Enzyme -2.04383 109.7 89
ADP-ribosylation factor-binding protein GGA1 GGA1 Tbio Non-IDG -1.92140 81.7 174
Ubiquitin carboxyl-terminal hydrolase 44 USP44 Tbio Enzyme -0.99299 11.2 189
Galectin-2 LGALS2 Tbio Non-IDG -1.12300 13.4 172