Development Level

Tbio 13 | 11,445

IMPC Phenotype

increased startle reflex 6 | 112
abnormal bone structure 4 | 187
increased heart weight 4 | 62
abnormal locomotor activation 2 | 16
abnormal startle reflex 2 | 15
decreased body weight 2 | 161
decreased circulating iron lev... 2 | 32
decreased erythrocyte cell num... 2 | 62
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased prepulse inhibition 2 | 82
increased blood urea nitrogen ... 2 | 48
increased circulating amylase ... 2 | 25
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 12 | 11,493
Kidney disease 11 | 430
Kidney cancer 9 | 2,613
ovarian cancer 9 | 8,520
Cancer 8 | 2,499
lung cancer 6 | 4,740
pancreatic cancer 6 | 2,398
Adenoma 5 | 167
Hypothyroidism 5 | 122
Obesity 5 | 678
medulloblastoma, large-cell 5 | 6,241
substance-related disorder 5 | 162
ACTH-secreting pituitary adenoma 4 | 9
Acrodysostosis 4 | 12
Acromegaly 4 | 51
Adrenal gland cancer 4 | 12
Beckwith-Wiedemann syndrome 4 | 44
Biliary tract cancer 4 | 19
Bone cancer 4 | 16
Brachydactyly 4 | 156
Carney complex 4 | 25
Cervix carcinoma 4 | 10
Cushing syndrome due to macronodular adrenal hyperplasia 4 | 5
Cushing's syndrome 4 | 48
DOID:3297 4 | 4
Fibrodysplasia ossificans progressiva 4 | 17
Fibrous dysplasia 4 | 15
Hyperphosphatemia 4 | 32
Hyperthyroidism 4 | 53
Hypoparathyroidism 4 | 41
Liver cancer 4 | 604
McCune Albright syndrome 4 | 19
Mccune-Albright Syndrome 4 | 4
Monostotic fibrous dysplasia 4 | 4
Multiple Endocrine Neoplasia Type 1 4 | 29
Ossifying fibroma 4 | 15
Pituitary Adenoma, Growth Hormone-Secreting, 1 4 | 5
Pituitary adenoma 4 | 38
Plummer's disease 4 | 11
Polycystic ovary syndrome 4 | 360
Primary pigmented nodular adrenocortical disease 4 | 13
Progressive osseous heteroplasia 4 | 4
Pseudohypoparathyroidism 4 | 18
Pseudohypoparathyroidism type 1C 4 | 4
Pseudohypoparathyroidism, Type 1A 4 | 4
Pseudohypoparathyroidism, Type 1B 4 | 5
Pseudopseudohypoparathyroidism 4 | 6
Small intestine cancer 4 | 12
Stomach cancer 4 | 30
Substance Withdrawal Syndrome 4 | 55
Thyroid cancer 4 | 36
ependymoma 4 | 4,679
osteosarcoma 4 | 7,950
pituitary cancer 4 | 1,972
psoriasis 4 | 6,694
Breast cancer 3 | 3,578
Osteoporosis 3 | 363
adult high grade glioma 3 | 3,801
ductal carcinoma in situ 3 | 1,745
glioblastoma 3 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
Astrocytoma, Pilocytic 2 | 3,081
Bilateral fifth finger clinodactyly 2 | 110
Coarse facial features 2 | 108
Concave bridge of nose 2 | 195
Curvature of little finger 2 | 110
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Fatigue 2 | 182
Gamma chain deficiency 2 | 7
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Leukemia 2 | 104
MYELODYSPLASTIC SYNDROME 2 | 53
Melanoma 2 | 711
Muscle Weakness 2 | 170
Pick disease 2 | 1,894
Poor growth 2 | 114
Radio-ulnar synostosis-amegakaryocytic thrombocytopenia syndrome 2 | 3
Radioulnar synostosis 2 | 35
Short stature 2 | 531
Skin cancer 2 | 469
Thickened facial skin with coarse facial features 2 | 108
Very poor growth 2 | 114
atypical teratoid / rhabdoid tumor 2 | 5,112
cystic fibrosis 2 | 1,696
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
Hypothermia, natural 1 | 17
Short middle phalanx of the 5th finger 1 | 13
Thyroid Hypoplasia 1 | 4
Triangular mouth 1 | 6

Tissue

Urinary Tract 9 | 16,678
Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Liver and Pancreas 7 | 16,750

Target Family

Non-IDG 7 | 12,091
Transcription Factor 3 | 1,400
Enzyme 1 | 4,145
TF/Epigenetic 1 | 38
Transporter 1 | 473

GWAS Trait

Renal function-related traits ... 13 | 13
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable E3 ubiquitin-protein ligase HECTD4 HECTD4 Tbio Enzyme -1.02570 11.0 0
MDS1 and EVI1 complex locus protein MDS1 MECOM Tbio Non-IDG -1.84060 124.5 0
Protein ALEX GNAS Tbio Non-IDG -2.63356 1389.7 509
Paired box protein Pax-8 PAX8 Tbio Transcription Factor -2.64765 442.1 540
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas GNAS Tbio Non-IDG -2.63356 1389.7 509
WD repeat-containing protein 72 WDR72 Tbio Non-IDG -0.84192 8.37 10
Breast carcinoma-amplified sequence 3 BCAS3 Tbio Non-IDG -1.24719 16.2 149
Homeobox protein unc-4 homolog UNCX Tbio Transcription Factor -1.05135 11.6 106
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short GNAS Tbio Non-IDG -2.63356 1389.7 509
Neuroendocrine secretory protein 55 GNAS Tbio Non-IDG -2.63356 1389.7 509