Development Level

Tbio 142 | 11,445
Tdark 24 | 6,588
Tchem 18 | 1,598
Tclin 7 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 11 | 979
decreased bone mineral content 6 | 151
increased mean corpuscular hem... 6 | 96
decreased erythrocyte cell num... 5 | 62
decreased bone mineral density 4 | 126
decreased hemoglobin content 4 | 68
embryonic lethality prior to t... 4 | 278
increased circulating alkaline... 4 | 122
increased total body fat amoun... 4 | 134
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
decreased circulating iron lev... 3 | 32
decreased circulating serum al... 3 | 82
decreased grip strength 3 | 116
decreased hematocrit 3 | 46
decreased leukocyte cell numbe... 3 | 73
decreased prepulse inhibition 3 | 82
decreased vertical activity 3 | 208
increased circulating iron lev... 3 | 30
increased lean body mass 3 | 172
preweaning lethality, incomple... 3 | 499
abnormal cranium morphology 2 | 36
abnormal embryo size 2 | 220
abnormal locomotor activation 2 | 16
abnormal startle reflex 2 | 15
decreased body weight 2 | 161
decreased circulating fructosa... 2 | 30
decreased lean body mass 2 | 135
decreased neutrophil cell numb... 2 | 42
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased circulating amylase ... 2 | 25
increased circulating total pr... 2 | 28
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
limb grasping 2 | 41
male infertility 2 | 123
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
short tibia 2 | 97
vertebral transformation 2 | 12
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
anophthalmia 1 | 33
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased heart left ventricle... 1 | 28
decreased mean platelet volume 1 | 25
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased red blood cell distr... 1 | 34
long tibia 1 | 25
microphthalmia 1 | 26
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
thin ventricular wall 1 | 24
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 128 | 11,493
osteosarcoma 108 | 7,950
ovarian cancer 106 | 8,520
psoriasis 85 | 6,694
medulloblastoma, large-cell 75 | 6,241
glioblastoma 72 | 5,792
atypical teratoid / rhabdoid tumor 63 | 5,112
ependymoma 62 | 4,679
group 3 medulloblastoma 61 | 4,104
lung cancer 55 | 4,740
adult high grade glioma 52 | 3,801
Breast cancer 46 | 3,578
Cancer 46 | 2,499
malignant mesothelioma 43 | 3,232
non-small cell lung cancer 43 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 42 | 3,291
invasive ductal carcinoma 42 | 2,951
Astrocytoma, Pilocytic 38 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,989
lung adenocarcinoma 37 | 2,716
pancreatic cancer 36 | 2,398
subependymal giant cell astrocytoma 36 | 2,287
tuberculosis 34 | 2,010
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
primitive neuroectodermal tumor 33 | 3,035
astrocytic glioma 32 | 2,597
lung carcinoma 32 | 2,843
oligodendroglioma 30 | 2,850
Peripheral vascular disease 29 | 87
cystic fibrosis 28 | 1,696
ductal carcinoma in situ 27 | 1,745
Kidney cancer 26 | 2,613
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
ulcerative colitis 26 | 1,819
breast carcinoma 25 | 1,638
Rheumatoid arthritis 24 | 1,191
interstitial cystitis 22 | 2,312
group 4 medulloblastoma 21 | 1,855
Anemia 20 | 365
colon cancer 19 | 1,478
pituitary cancer 19 | 1,972
Autosomal recessive predisposition 18 | 1,442
Pick disease 18 | 1,894
Schizophrenia 18 | 1,160
astrocytoma 18 | 1,146
dermatomyositis 17 | 966
adrenocortical carcinoma 16 | 1,428
cutaneous lupus erythematosus 16 | 1,057
primary pancreatic ductal adenocarcinoma 16 | 1,109
diabetes mellitus 15 | 1,728
Obesity 14 | 678
active ulcerative colitis 14 | 764
esophageal adenocarcinoma 14 | 737
primary Sjogren syndrome 14 | 735
Acquired metabolic disease 13 | 336
Bipolar Disorder 13 | 666
Crohn's disease 13 | 321
juvenile dermatomyositis 13 | 1,187
pancreatic carcinoma 13 | 562
Hemolytic anemia 12 | 77
Melanoma 12 | 711
spina bifida 12 | 1,074
Kidney disease 11 | 430
Osteoporosis 11 | 363
Parkinson's disease 11 | 392
Type 2 diabetes mellitus 11 | 272
acute myeloid leukemia 11 | 783
acute quadriplegic myopathy 11 | 1,158
Alzheimer's disease 10 | 658
Atopic dermatitis 10 | 952
Intellectual disability 10 | 1,016
Multiple myeloma 10 | 1,332
Prostatic Neoplasms 10 | 495
Splenomegaly 10 | 190
Thalassemia 10 | 53
Waldenstrons macroglobulinemia 10 | 765
aldosterone-producing adenoma 10 | 665
chronic rhinosinusitis 10 | 512
hepatocellular carcinoma 10 | 547
nasopharyngeal carcinoma 10 | 1,058
pediatric high grade glioma 10 | 1,064
Breast Neoplasms 9 | 445
Coronary artery disease 9 | 268
Diabetes Mellitus, Non-Insulin-Dependent 9 | 145
Epilepsy 9 | 792
Mammary Neoplasms 9 | 425
Polycystic ovary syndrome 9 | 360
active Crohn's disease 9 | 922
fibroadenoma 9 | 559
gastric carcinoma 9 | 807
Chronic Lymphocytic Leukemia 8 | 262
Diabetes Mellitus, Type 2 8 | 142
Endometriosis 8 | 540
Heart disease 8 | 306
Hypertension 8 | 396
Multiple Sclerosis 8 | 540
Myocardial Ischemia 8 | 169
Vascular disease 8 | 319
gastric cancer 8 | 459
non primary Sjogren syndrome sicca 8 | 891

Tissue

Digestive Tract 182 | 17,369
Endocrine System 182 | 18,159
Blood and immune system 181 | 16,909
Female tissues 181 | 17,400
Nervous System 180 | 16,725
Urinary Tract 178 | 16,678
Male tissues 177 | 17,142
Skin and soft tissues 177 | 17,230
Liver and Pancreas 176 | 16,750
Respiratory system 172 | 16,393
Cardiovascular System 168 | 15,192

Target Family

Non-IDG 99 | 12,091
Transcription Factor 35 | 1,400
Enzyme 31 | 4,145
Kinase 8 | 634
Transporter 5 | 473
TF/Epigenetic 4 | 38
Ion Channel 3 | 344
Epigenetic 2 | 242
Nuclear Receptor 2 | 48
GPCR 1 | 408
oGPCR 1 | 421

GWAS Trait

Red blood cell count 191 | 191
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier family 12 member 7 SLC12A7 Tbio Transporter -1.46102 28.2 156
Olfactory receptor 52A1 OR52A1 Tdark oGPCR 0.18 1.00 92
T-box transcription factor TBX6 TBX6 Tbio Transcription Factor -1.78720 63.0 315
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
U6 snRNA-associated Sm-like protein LSm4 LSM4 Tbio Non-IDG -2.13782 132.0 149
Protein TASOR FAM208A Tbio Non-IDG -0.45230 1.33 12
D-3-phosphoglycerate dehydrogenase PHGDH Tbio Enzyme -3.17330 1408.2 293
Pro-neuregulin-4, membrane-bound isoform NRG4 Tbio Non-IDG -1.33564 24.6 137
Protein BTG2 BTG2 Tbio Non-IDG -2.10376 142.7 209
Zonadhesin ZAN Tdark Non-IDG 0.00000 0