Development Level

Tbio 6 | 11,445
Tchem 6 | 1,598
Tdark 5 | 6,588
Tclin 1 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
decreased circulating alkaline... 1 | 46
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
limb grasping 1 | 41
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 17 | 11,493
medulloblastoma, large-cell 11 | 6,241
osteosarcoma 11 | 7,950
ovarian cancer 9 | 8,520
psoriasis 8 | 6,694
Breast cancer 7 | 3,578
adult high grade glioma 7 | 3,801
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
lung cancer 7 | 4,740
group 3 medulloblastoma 6 | 4,104
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
primitive neuroectodermal tumor 5 | 3,035
Amyotrophic lateral sclerosis 4 | 451
Kidney cancer 4 | 2,613
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
Astrocytoma, Pilocytic 3 | 3,081
Gingivitis 3 | 29
Obesity 3 | 678
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
acute quadriplegic myopathy 3 | 1,158
colon cancer 3 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
tuberculosis 3 | 2,010
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Cataract 2 | 297
Dementia 2 | 175
Glaucoma 2 | 239
Heart conduction disease 2 | 83
Intellectual disability 2 | 1,016
Lens Opacities 2 | 231
Liver cancer 2 | 604
Melanoma 2 | 711
Mouth Infection Prevention 2 | 5
Multiple Sclerosis 2 | 540
Multiple myeloma 2 | 1,332
Nystagmus 2 | 317
Rheumatoid arthritis 2 | 1,191
Skin cancer 2 | 469
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,855
lung adenocarcinoma 2 | 2,716
nephrosclerosis 2 | 333
non diabetic and post-ischemic heart failure 2 | 200
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
ulcerative colitis 2 | 1,819
Abnormality of retinal pigmentation 1 | 111
Abnormality of the retinal vasculature 1 | 59
Atypical scarring of skin 1 | 62
Autoimmune thrombocytopenia 1 | 22
Brain Edema 1 | 50
COPD 1 | 118
Chronic otitis media 1 | 52
Conductive hearing loss 1 | 123
Congenital anomaly of testis 1 | 52
Decreased antibody level in blood 1 | 35
Difficulties with night vision 1 | 87
Hirschsprung's disease 1 | 46
Hyperinsulinism 1 | 133
Hypogammaglobulinemia 1 | 35
Immune thrombocytopenic purpura 1 | 24
Immunologic Deficiency Syndromes 1 | 113
Keratoconus 1 | 113
Kidney Diseases 1 | 114
Lymphadenopathy 1 | 62
Lymphoma 1 | 81
Lymphopenia 1 | 67
Megacolon 1 | 29
Night Blindness 1 | 101
Night blindness, progressive 1 | 51
Pallor of optic disc 1 | 39
Photodysphoria 1 | 121
Photophobia 1 | 121
Purpura 1 | 43
Recurrent respiratory infections 1 | 141
Retinal pigment epithelial abnormality 1 | 111
Schnyder Corneal Dystrophy 1 | 23
Sensorineural Hearing Loss (disorder) 1 | 284
Severe acute respiratory syndrome 1 | 27
Squamous cell carcinoma 1 | 129
ear infection chronic 1 | 52
non-inflammatory breast cancer 1 | 66
non-small cell lung carcinoma 1 | 317

Tissue

Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Male tissues 18 | 17,142
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678
Blood and immune system 17 | 16,909
Liver and Pancreas 17 | 16,750
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 9 | 12,091
Transporter 3 | 473
Enzyme 2 | 4,145
Ion Channel 2 | 344
GPCR 1 | 408
Kinase 1 | 634

GWAS Trait

Recurrent major depressive dis... 18 | 18
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Membrane-spanning 4-domains subfamily A member 12 MS4A12 Tdark Non-IDG -0.40280 3.06 54
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
E3 ubiquitin-protein ligase RNF19A RNF19A Tbio Enzyme -1.12489 15.5 142
Ras-GEF domain-containing family member 1A RASGEF1A Tdark Non-IDG -0.56596 3.21 50
Tripartite motif-containing protein 55 TRIM55 Tdark Non-IDG -0.69631 4.68 132
Uncharacterized protein KIAA1671 KIAA1671 Tdark Non-IDG 0.56 0.19 10
Claudin-5 CLDN5 Tbio Non-IDG -2.58968 349.4 300
B-lymphocyte antigen CD20 MS4A1 Tclin Non-IDG -1.94302 79.5 2278
Solute carrier family 22 member 1 SLC22A1 Tchem Transporter -2.16768 152.4 206
Secreted frizzled-related protein 3 FRZB Tbio Non-IDG -2.51623 308.4 252