Development Level

Tbio 70 | 11,178
Tchem 15 | 1,885
Tdark 15 | 6,569
Tclin 10 | 612

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal sleep behavior 3 | 70
decreased prepulse inhibition 3 | 82
increased startle reflex 3 | 112
abnormal craniofacial morpholo... 2 | 33
decreased caudal vertebrae num... 2 | 53
decreased circulating choleste... 2 | 93
decreased fasted circulating g... 2 | 65
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
improved glucose tolerance 2 | 79
increased heart weight 2 | 62
increased lean body mass 2 | 172
irregularly shaped pupil 2 | 7
shortened RR interval 2 | 17
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal embryonic autopod pla... 1 | 2
abnormal eye morphology 1 | 68
abnormal eyelid morphology 1 | 7
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head size 1 | 6
abnormal hindbrain morphology 1 | 10
abnormal iris morphology 1 | 13
abnormal lip morphology 1 | 2
abnormal locomotor behavior 1 | 24
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placement of pupils 1 | 6
abnormal placenta morphology 1 | 5
abnormal retinal blood vessel ... 1 | 26
abnormal sensory capabilities-... 1 | 8
abnormal urinary bladder morph... 1 | 11
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased coping response 1 | 8
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased threshold for audito... 1 | 26
edema 1 | 59
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
increased bone mineral content 1 | 108
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased vertical activity 1 | 24
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
sclerocornea 1 | 2
short tibia 1 | 97
thrombocytopenia 1 | 56
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 78 | 11,192
ovarian cancer 58 | 8,297
osteosarcoma 57 | 7,766
medulloblastoma, large-cell 54 | 6,086
atypical teratoid / rhabdoid tumor 51 | 4,971
glioblastoma 45 | 5,635
ependymoma 42 | 4,559
psoriasis 39 | 6,514
Heart conduction disease 38 | 82
Breast cancer 37 | 3,469
Astrocytoma, Pilocytic 35 | 3,006
lung adenocarcinoma 34 | 2,627
lung cancer 34 | 4,607
group 3 medulloblastoma 33 | 4,002
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,872
primitive neuroectodermal tumor 33 | 2,957
invasive ductal carcinoma 32 | 2,867
adult high grade glioma 31 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,204
lung carcinoma 31 | 2,755
Kidney cancer 30 | 2,548
oligodendroglioma 30 | 2,768
pituitary cancer 30 | 1,915
astrocytic glioma 29 | 2,530
malignant mesothelioma 28 | 3,135
pancreatic cancer 25 | 2,322
interstitial cystitis 24 | 2,237
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,902
Pick disease 23 | 1,856
non-small cell lung cancer 23 | 2,799
subependymal giant cell astrocytoma 23 | 2,230
cystic fibrosis 19 | 1,629
ductal carcinoma in situ 19 | 1,686
group 4 medulloblastoma 19 | 1,806
tuberculosis 18 | 1,963
Schizophrenia 16 | 1,136
breast carcinoma 15 | 1,589
primary pancreatic ductal adenocarcinoma 14 | 1,071
ulcerative colitis 14 | 1,765
Cancer 13 | 2,388
adrenocortical carcinoma 13 | 1,385
colon cancer 13 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,911
Autosomal recessive predisposition 12 | 1,407
diabetes mellitus 12 | 1,683
Intellectual disability 11 | 998
active Crohn's disease 11 | 882
acute quadriplegic myopathy 11 | 1,133
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 492
Epilepsy 10 | 775
aldosterone-producing adenoma 10 | 646
dermatomyositis 10 | 941
Amyotrophic lateral sclerosis 9 | 437
Down syndrome 9 | 480
Duchenne muscular dystrophy 9 | 587
Heart disease 9 | 288
Multiple myeloma 9 | 1,296
pediatric high grade glioma 9 | 1,035
Atrial Fibrillation 8 | 120
Bipolar Disorder 8 | 646
Dull intelligence 8 | 634
Liver cancer 8 | 589
Low intelligence 8 | 634
Mental Retardation 8 | 634
Mental deficiency 8 | 634
Poor school performance 8 | 634
Rheumatoid arthritis 8 | 1,156
Seizures 8 | 584
chronic rhinosinusitis 8 | 505
fibroadenoma 8 | 538
juvenile dermatomyositis 8 | 1,147
nasopharyngeal carcinoma 8 | 1,024
pancreatic carcinoma 8 | 555
spina bifida 8 | 1,053
Atopic dermatitis 7 | 915
Cardiac Arrhythmia 7 | 101
Liver Cirrhosis, Experimental 7 | 733
Short stature 7 | 514
gastric carcinoma 7 | 781
head and neck cancer 7 | 263
non primary Sjogren syndrome sicca 7 | 861
non-small cell lung carcinoma 7 | 302
Asthma 6 | 370
Autistic Disorder 6 | 358
Endometrial cancer 6 | 301
Long QT syndrome 6 | 39
Muscle hypotonia 6 | 562
Prostatic Neoplasms 6 | 472
Skin cancer 6 | 451
acute myeloid leukemia 6 | 760
mucosa-associated lymphoid tissue lymphoma 6 | 473
Glaucoma 5 | 232
Multiple Sclerosis 5 | 527
astrocytoma 5 | 1,113
esophageal adenocarcinoma 5 | 696
hepatocellular carcinoma 5 | 536
limb girdle muscular dystrophy 2A 5 | 208
medulloblastoma 5 | 702
primary Sjogren syndrome 5 | 710
progressive supranuclear palsy 5 | 656

Tissue

Endocrine System 106 | 18,159
Digestive Tract 103 | 17,369
Liver and Pancreas 103 | 16,750
Male tissues 103 | 17,142
Urinary Tract 103 | 16,678
Skin and soft tissues 102 | 17,230
Female tissues 101 | 17,400
Blood and immune system 100 | 16,909
Respiratory system 100 | 16,393
Nervous System 99 | 16,725
Cardiovascular System 97 | 15,192

Target Family

Non-IDG 56 | 12,091
Enzyme 22 | 4,145
Ion Channel 11 | 344
Transcription Factor 8 | 1,400
Transporter 6 | 473
Kinase 4 | 634
Epigenetic 3 | 242

GWAS Trait

QT interval 110 | 110
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 GNG12 Tbio Non-IDG -0.39851 2.26 42
UNC119-binding protein C5orf30 C5orf30 Tdark Non-IDG -0.56517 3.61 7
Rho GTPase-activating protein 24 ARHGAP24 Tbio Enzyme -1.07229 15.5 169
Centrosomal protein of 85 kDa-like CEP85L Tbio Non-IDG -0.11180 1.27 56
Claudin-14 CLDN14 Tbio Non-IDG -1.58115 36.2 206
Sarcalumenin SRL Tdark Non-IDG -2.06462 109.4 22
Inactive ubiquitin carboxyl-terminal hydrolase 50 USP50 Tdark Enzyme -0.39794 3.10 99
Intersectin-1 ITSN1 Tbio Non-IDG -1.78795 72.0 58
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Krueppel-like factor 12 KLF12 Tbio Transcription Factor -1.36344 19.7 185