Development Level

Tbio 78 | 11,651
Tdark 15 | 6,593
Tclin 10 | 612
Tchem 7 | 1,388

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal sleep behavior 3 | 70
decreased prepulse inhibition 3 | 82
increased startle reflex 3 | 112
abnormal craniofacial morpholo... 2 | 33
decreased caudal vertebrae num... 2 | 53
decreased circulating choleste... 2 | 93
decreased fasted circulating g... 2 | 65
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
improved glucose tolerance 2 | 79
increased heart weight 2 | 62
increased lean body mass 2 | 172
irregularly shaped pupil 2 | 7
shortened RR interval 2 | 17
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal embryonic autopod pla... 1 | 2
abnormal eye morphology 1 | 68
abnormal eyelid morphology 1 | 7
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head size 1 | 6
abnormal hindbrain morphology 1 | 10
abnormal iris morphology 1 | 13
abnormal lip morphology 1 | 2
abnormal locomotor behavior 1 | 24
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placement of pupils 1 | 6
abnormal placenta morphology 1 | 5
abnormal retinal blood vessel ... 1 | 26
abnormal sensory capabilities-... 1 | 8
abnormal urinary bladder morph... 1 | 11
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased coping response 1 | 8
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased threshold for audito... 1 | 26
edema 1 | 59
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
increased bone mineral content 1 | 108
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased vertical activity 1 | 24
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
sclerocornea 1 | 2
short tibia 1 | 97
thrombocytopenia 1 | 56
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 78 | 11,493
ovarian cancer 58 | 8,520
osteosarcoma 57 | 7,950
medulloblastoma, large-cell 54 | 6,241
atypical teratoid / rhabdoid tumor 51 | 5,112
glioblastoma 45 | 5,792
ependymoma 42 | 4,679
psoriasis 39 | 6,694
Heart conduction disease 38 | 83
Breast cancer 37 | 3,578
Astrocytoma, Pilocytic 35 | 3,081
lung adenocarcinoma 34 | 2,716
lung cancer 34 | 4,740
group 3 medulloblastoma 33 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
primitive neuroectodermal tumor 33 | 3,035
invasive ductal carcinoma 32 | 2,951
adult high grade glioma 31 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
lung carcinoma 31 | 2,843
Kidney cancer 30 | 2,613
oligodendroglioma 30 | 2,850
pituitary cancer 30 | 1,972
astrocytic glioma 29 | 2,597
malignant mesothelioma 28 | 3,232
pancreatic cancer 25 | 2,398
interstitial cystitis 24 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
Pick disease 23 | 1,894
non-small cell lung cancer 23 | 2,890
subependymal giant cell astrocytoma 23 | 2,287
cystic fibrosis 19 | 1,696
ductal carcinoma in situ 19 | 1,745
group 4 medulloblastoma 19 | 1,855
tuberculosis 18 | 2,010
Schizophrenia 16 | 1,160
breast carcinoma 15 | 1,638
primary pancreatic ductal adenocarcinoma 14 | 1,109
ulcerative colitis 14 | 1,819
Cancer 13 | 2,499
adrenocortical carcinoma 13 | 1,428
colon cancer 13 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Autosomal recessive predisposition 12 | 1,442
diabetes mellitus 12 | 1,728
Intellectual disability 11 | 1,016
active Crohn's disease 11 | 922
acute quadriplegic myopathy 11 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
Epilepsy 10 | 792
aldosterone-producing adenoma 10 | 665
dermatomyositis 10 | 966
Amyotrophic lateral sclerosis 9 | 451
Down syndrome 9 | 499
Duchenne muscular dystrophy 9 | 601
Heart disease 9 | 306
Multiple myeloma 9 | 1,332
pediatric high grade glioma 9 | 1,064
Atrial Fibrillation 8 | 124
Bipolar Disorder 8 | 666
Dull intelligence 8 | 645
Liver cancer 8 | 604
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Rheumatoid arthritis 8 | 1,191
Seizures 8 | 596
chronic rhinosinusitis 8 | 512
fibroadenoma 8 | 559
juvenile dermatomyositis 8 | 1,187
nasopharyngeal carcinoma 8 | 1,058
pancreatic carcinoma 8 | 562
spina bifida 8 | 1,074
Atopic dermatitis 7 | 952
Cardiac Arrhythmia 7 | 103
Liver Cirrhosis, Experimental 7 | 769
Short stature 7 | 531
gastric carcinoma 7 | 807
head and neck cancer 7 | 271
non primary Sjogren syndrome sicca 7 | 891
non-small cell lung carcinoma 7 | 317
Asthma 6 | 385
Autistic Disorder 6 | 364
Endometrial cancer 6 | 311
Long QT syndrome 6 | 39
Muscle hypotonia 6 | 571
Prostatic Neoplasms 6 | 495
Skin cancer 6 | 469
acute myeloid leukemia 6 | 783
mucosa-associated lymphoid tissue lymphoma 6 | 484
Glaucoma 5 | 239
Multiple Sclerosis 5 | 540
active ulcerative colitis 5 | 764
astrocytoma 5 | 1,146
esophageal adenocarcinoma 5 | 737
hepatocellular carcinoma 5 | 547
limb girdle muscular dystrophy 2A 5 | 213
primary Sjogren syndrome 5 | 735
progressive supranuclear palsy 5 | 676

Tissue

Endocrine System 106 | 18,159
Digestive Tract 103 | 17,369
Liver and Pancreas 103 | 16,750
Male tissues 103 | 17,142
Urinary Tract 103 | 16,678
Skin and soft tissues 102 | 17,230
Female tissues 101 | 17,400
Blood and immune system 100 | 16,909
Respiratory system 100 | 16,393
Nervous System 99 | 16,725
Cardiovascular System 97 | 15,192

Target Family

Non-IDG 56 | 12,091
Enzyme 22 | 4,145
Ion Channel 11 | 344
Transcription Factor 8 | 1,400
Transporter 6 | 473
Kinase 4 | 634
Epigenetic 3 | 242

GWAS Trait

QT interval 110 | 110
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
A disintegrin and metalloproteinase with thrombospondin motifs 6 ADAMTS6 Tdark Enzyme -0.67364 4.37 40
Protein wntless homolog WLS Tbio Non-IDG -2.50699 316.3 71
cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A Tclin Enzyme -2.09039 125.7 168
Claudin-15 CLDN15 Tbio Non-IDG -1.33932 19.3 154
Putative uncharacterized protein encoded by LINC00337 LINC00337 Tdark Non-IDG 0.00000 0
Potassium voltage-gated channel subfamily E member 1 KCNE1 Tbio Ion Channel -2.67495 441.7 193
Dipeptidyl aminopeptidase-like protein 6 DPP6 Tbio Enzyme -2.06587 114.8 131
Tripartite motif-containing protein 74 TRIM74 Tdark Non-IDG 0.17 0.39 71
TSC22 domain family protein 4 TSC22D4 Tdark Transcription Factor -0.22432 2.49 87
Lipopolysaccharide-induced tumor necrosis factor-alpha factor LITAF Tbio Transcription Factor -2.03585 113.9 202