Development Level

Tbio 31 | 10,625
Tchem 11 | 1,890
Tdark 9 | 7,003
Tclin 7 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

decreased lumbar vertebrae num... 2 | 62
decreased prepulse inhibition 2 | 52
hyperactivity 2 | 108
increased lean body mass 2 | 107
increased sacral vertebrae num... 2 | 62
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal embryo size 1 | 112
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retinal blood vessel ... 1 | 18
abnormal retinal outer nuclear... 1 | 5
abnormal rib morphology 1 | 28
abnormal sensory capabilities/... 1 | 3
abnormal thoracic vertebrae mo... 1 | 16
abnormal urinary bladder morph... 1 | 2
decreased CD4-positive, CD25-p... 1 | 24
decreased NK T cell number 1 | 28
decreased T-helper cell number 1 | 4
decreased bone mineral content 1 | 157
decreased fasted circulating g... 1 | 49
decreased lactate dehydrogenas... 1 | 14
decreased mature B cell number 1 | 25
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
herniated abdominal wall 1 | 4
hydrops fetalis 1 | 22
increased CD4-positive, CD25-p... 1 | 18
increased body length 1 | 20
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased effector memory CD4-... 1 | 15
increased grip strength 1 | 83
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38
increased vertical activity 1 | 18
thick ventricular wall 1 | 7

Disease

medulloblastoma, large-cell 32 | 6,234
osteosarcoma 32 | 7,933
ovarian cancer 30 | 8,484
Heart conduction disease 28 | 65
atypical teratoid / rhabdoid tumor 26 | 4,369
glioblastoma 22 | 5,572
lung adenocarcinoma 20 | 2,713
lung carcinoma 20 | 2,844
primitive neuroectodermal tumor 20 | 3,031
psoriasis 20 | 6,685
Breast cancer 18 | 3,094
pilocytic astrocytoma 18 | 3,086
ependymoma 17 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,956
invasive ductal carcinoma 17 | 2,950
pituitary cancer 16 | 1,972
lung cancer 15 | 4,466
oligodendroglioma 15 | 2,849
pancreatic cancer 15 | 2,300
Carcinoma 14 | 2,147
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
non-small cell lung cancer 13 | 2,798
Pick disease 12 | 1,893
interstitial cystitis 12 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,988
malignant mesothelioma 12 | 3,162
medulloblastoma 12 | 1,524
pediatric high grade glioma 12 | 2,712
subependymal giant cell astrocytoma 12 | 2,287
astrocytic glioma 11 | 2,241
Cancer 10 | 2,346
colon cancer 10 | 1,475
ulcerative colitis 10 | 2,087
adrenocortical carcinoma 9 | 1,427
ductal carcinoma in situ 9 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
Heart disease 8 | 279
adult high grade glioma 8 | 2,148
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
group 4 medulloblastoma 8 | 1,875
Atrial Fibrillation 7 | 110
Duchenne muscular dystrophy 7 | 602
breast carcinoma 7 | 1,614
diabetes mellitus 7 | 1,663
group 3 medulloblastoma 7 | 2,254
primary pancreatic ductal adenocarcinoma 7 | 1,271
sonic hedgehog group medulloblastoma 7 | 1,482
Amyotrophic Lateral Sclerosis 6 | 431
Down syndrome 6 | 548
Epilepsy 6 | 346
Long QT syndrome 6 | 52
active Crohn's disease 6 | 918
aldosterone-producing adenoma 6 | 664
astrocytoma 6 | 1,493
atypical teratoid/rhabdoid tumor 6 | 1,095
cystic fibrosis 6 | 1,665
fibroadenoma 6 | 557
pancreatic carcinoma 6 | 567
Multiple myeloma 5 | 1,327
Rheumatoid Arthritis 5 | 1,160
Romano-Ward Syndrome 5 | 12
acute quadriplegic myopathy 5 | 1,157
dermatomyositis 5 | 933
juvenile dermatomyositis 5 | 1,189
posterior fossa group A ependymoma 5 | 1,511
posterior fossa group B ependymoma 5 | 1,530
spina bifida 5 | 1,064
Congenital long QT syndrome 4 | 8
Diabetes Mellitus, Experimental 4 | 106
Multiple Sclerosis 4 | 498
Neurodegenerative disease 4 | 383
Schizophrenia 4 | 501
Sensorineural hearing loss 4 | 107
Short QT syndrome 4 | 12
Timothy syndrome 4 | 12
acute myeloid leukemia 4 | 780
gastric carcinoma 4 | 832
non-small cell lung carcinoma 4 | 413
progressive supranuclear palsy 4 | 674
tuberculosis 4 | 1,557
Alzheimer's disease 3 | 644
Becker muscular dystrophy 3 | 187
Cardiovascular system disease 3 | 194
Juvenile arthritis 3 | 124
Neuropathy 3 | 210
Parkinson's disease 3 | 364
Prostatic Neoplasms 3 | 471
Status Epilepticus 3 | 85
Substance-Related Disorders 3 | 114
Ventricular Fibrillation 3 | 10
chronic rhinosinusitis 3 | 512
cystic fibrosis and chronic rhinosinusitis 3 | 213
esophageal adenocarcinoma 3 | 737
head and neck cancer 3 | 270
hereditary spastic paraplegia 3 | 313
limb girdle muscular dystrophy 2A 3 | 156
nasopharyngeal carcinoma 3 | 1,056
primary Sjogren syndrome 3 | 789
tuberculosis and treatment for 3 months 3 | 327
tuberculosis and treatment for 6 months 3 | 686

Tissue

Blood and immune system 58 | 17,995
Cardiovascular System 58 | 17,958
Digestive Tract 58 | 18,473
Endocrine System 58 | 18,512
Female tissues 58 | 18,647
Male tissues 58 | 17,969
Nervous System 58 | 18,561
Skin and soft tissues 58 | 18,115
Urinary Tract 58 | 18,444
Liver and Pancreas 57 | 18,136
Respiratory system 57 | 17,484

Target Family

Non-IDG 26 | 11,971
Enzyme 10 | 4,146
Ion Channel 9 | 341
Transporter 6 | 473
Kinase 3 | 634
Transcription Factor 3 | 1,400
Epigenetic 1 | 242

GWAS Trait

QT interval 58 | 58
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1/FVC r... 192 | 192
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 112 | 112
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1/FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myelin basic protein MBP Tbio Non-IDG -3.69577 5257.0 715
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Transmembrane protein 44 TMEM44 Tdark Non-IDG 0.95 0.12 8
Dermatopontin DPT Tbio Non-IDG -3.07361 1232.9 77
DNA ligase 3 LIG3 Tbio Enzyme -2.71696 505.0 223
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein NOS1AP Tbio Enzyme -2.09236 133.4 142
Titin TTN Tbio Kinase -3.19894 1643.9 116
Potassium voltage-gated channel subfamily E member 1 KCNE1 Tbio Ion Channel -2.63112 407.4 169
CCR4-NOT transcription complex subunit 1 CNOT1 Tbio Non-IDG -2.08441 115.0 30
Rho GTPase-activating protein 10 ARHGAP10 Tbio Enzyme -1.25836 19.4 67