Development Level

Tbio 8 | 11,445

IMPC Phenotype

abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased glycosylated hemoglo... 1 | 1
decreased total body fat amoun... 1 | 207
female infertility 1 | 60
head bobbing 1 | 5
hypoactivity 1 | 132
increased mean platelet volume 1 | 45
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 5 | 11,493
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
ovarian cancer 4 | 8,520
Astrocytoma, Pilocytic 3 | 3,081
Waldenstrons macroglobulinemia 3 | 765
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
lung carcinoma 3 | 2,843
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Parkinson's disease 2 | 392
Pick disease 2 | 1,894
astrocytic glioma 2 | 2,597
dermatomyositis 2 | 966
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Abnormal vision 1 | 52
Addison Disease 1 | 18
Adrenal cortical hypofunction 1 | 23
Adrenoleukodystrophy 1 | 29
Aphasia 1 | 26
Autoimmune hepatitis 1 | 11
Big calvaria 1 | 147
Cerebellar hypoplasia and atrophy 1 | 41
Chondrodysplasia punctata 1 | 41
Congenital anomaly of face 1 | 56
Congenital clubfoot 1 | 109
Congenital pes cavus 1 | 88
Cystic kidney 1 | 30
Dilated ventricles (finding) 1 | 121
Distortion of face 1 | 46
Dysmorphic facies 1 | 46
Dysmyelination of the brain 1 | 6
Elevated gonadotropins 1 | 15
Elliptocytosis, Hereditary 1 | 9
Extinguished electroretinogram 1 | 15
Frontal bossing 1 | 157
Funny looking face 1 | 46
Generalized osteopenia 1 | 99
Gonadal Dysgenesis 1 | 28
Gonadal Dysgenesis, Mixed 1 | 19
Hepatitis 1 | 67
Hepatitis B 1 | 108
Hepatitis C 1 | 94
Hereditary elliptocytosis 1 | 22
High forehead 1 | 102
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Human immunodeficiency virus infectious disease 1 | 138
Hypoplasia of corpus callosum 1 | 90
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Infantile Refsum disease 1 | 23
Large bregma sutures 1 | 46
Large fontanelle 1 | 46
Large, late-closing fontanelle 1 | 46
Laryngotracheitis 1 | 10
Late fontanel closure 1 | 28
Long narrow head 1 | 75
Low Vision 1 | 174
Lymphoid leukemia 1 | 160
Narrow cranium shape 1 | 75
Narrow head shape 1 | 75
Narrow skull shape 1 | 75
Neonatal Hypotonia 1 | 64
Neonatal adrenoleukodystrophy 1 | 14
Osteopenia 1 | 99
Osteoporosis 1 | 363
Polyhydramnios 1 | 108
Polymicrogyria 1 | 48
Premature ovarian failure 1 | 65
Primary physiologic amenorrhea 1 | 55
Pure gonadal dysgenesis 1 | 19
Refsum disease 1 | 20
Renal cyst 1 | 30
Retrognathia 1 | 54
Sensorineural Hearing Loss (disorder) 1 | 284
Sensorineural hearing loss 1 | 106
Steatohepatitis 1 | 44
Syphilis 1 | 17
Tall forehead 1 | 102
Thoracic hypoplasia 1 | 14
Turridolichocephaly 1 | 75
Urinary bladder cancer 1 | 36
Visual Impairment 1 | 174
West Syndrome 1 | 28
White matter dysmyelination/demyelination 1 | 6
Wide bregma sutures 1 | 46
Zellweger syndrome 1 | 37
alpha-methylacyl-CoA racemase deficiency 1 | 9
facial deformity 1 | 46
hereditary spastic paraplegia 1 | 318

Tissue

Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Skin and soft tissues 8 | 17,230
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Liver and Pancreas 6 | 16,750
Respiratory system 6 | 16,393
Urinary Tract 6 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 2 | 4,145

GWAS Trait

Pyoderma gangrenosum in inflam... 8 | 8
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serpin B12 SERPINB12 Tbio Non-IDG -0.56624 4.27 155
Ubiquitin carboxyl-terminal hydrolase 15 USP15 Tbio Enzyme -1.64742 41.6 242
Glycophorin-C GYPC Tbio Non-IDG -2.88194 722.9 302
Peroxisomal multifunctional enzyme type 2 HSD17B4 Tbio Non-IDG -2.17283 152.2 275
Actin-related protein 2/3 complex subunit 2 ARPC2 Tbio Non-IDG -1.31089 16.9 270
Synaptotagmin-4 SYT4 Tbio Non-IDG -1.63958 44.4 245
Synapsin-3 SYN3 Tbio Non-IDG -1.99912 100.6 110
GTP-binding protein Rit2 RIT2 Tbio Enzyme -2.89394 791.7 163