Development Level

Tbio 68 | 11,651
Tchem 15 | 1,388
Tclin 8 | 612
Tdark 6 | 6,593

Collection

RFA-RM-18-021 3 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 11 | 979
enlarged heart 4 | 210
increased circulating alkaline... 4 | 122
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
abnormal lens morphology 3 | 81
decreased circulating glucose ... 3 | 126
embryonic lethality prior to t... 3 | 278
increased startle reflex 3 | 112
prenatal lethality prior to he... 3 | 87
preweaning lethality, incomple... 3 | 499
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
cataract 2 | 92
decreased caudal vertebrae num... 2 | 53
decreased circulating serum al... 2 | 82
decreased erythrocyte cell num... 2 | 62
embryonic growth retardation 2 | 106
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal incisor color 1 | 3
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal ovary morphology 1 | 7
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
absent epididymis 1 | 3
absent pinna reflex 1 | 23
absent vibrissae 1 | 12
corneal opacity 1 | 32
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating sodium l... 1 | 22
decreased circulating unsatura... 1 | 2
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged kidney 1 | 14
enlarged testis 1 | 6
eyelids fail to open 1 | 3
hyperactivity 1 | 148
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
kyphosis 1 | 5
thick ventricular wall 1 | 7

Disease

Carcinoma 75 | 11,493
ovarian cancer 57 | 8,520
psoriasis 48 | 6,694
osteosarcoma 46 | 7,950
glioblastoma 39 | 5,792
medulloblastoma, large-cell 38 | 6,241
Breast cancer 36 | 3,578
atypical teratoid / rhabdoid tumor 36 | 5,112
ependymoma 35 | 4,679
lung cancer 33 | 4,740
adult high grade glioma 32 | 3,801
Astrocytoma, Pilocytic 31 | 3,081
invasive ductal carcinoma 30 | 2,951
Cancer 27 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
oligodendroglioma 27 | 2,850
group 3 medulloblastoma 25 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
lung adenocarcinoma 25 | 2,716
malignant mesothelioma 25 | 3,232
Kidney cancer 23 | 2,613
interstitial cystitis 23 | 2,312
primitive neuroectodermal tumor 23 | 3,035
lung carcinoma 22 | 2,843
pancreatic cancer 22 | 2,398
cystic fibrosis 21 | 1,696
astrocytic glioma 20 | 2,597
ductal carcinoma in situ 20 | 1,745
pituitary cancer 19 | 1,972
non-small cell lung cancer 18 | 2,890
ulcerative colitis 18 | 1,819
primary pancreatic ductal adenocarcinoma 17 | 1,109
subependymal giant cell astrocytoma 17 | 2,287
breast carcinoma 14 | 1,638
diabetes mellitus 14 | 1,728
adrenocortical carcinoma 13 | 1,428
gastric carcinoma 13 | 807
Pick disease 12 | 1,894
Schizophrenia 12 | 1,160
nasopharyngeal carcinoma 12 | 1,058
tuberculosis 12 | 2,010
Atopic dermatitis 11 | 952
Duchenne muscular dystrophy 11 | 601
Hypertension 11 | 396
colon cancer 11 | 1,478
Depressive disorder 10 | 409
Endometriosis 10 | 540
Essential Hypertension 10 | 94
astrocytoma 10 | 1,146
group 4 medulloblastoma 10 | 1,855
Autosomal recessive predisposition 9 | 1,442
Epilepsy 9 | 792
Heart disease 9 | 306
Obesity 9 | 678
Prostatic Neoplasms 9 | 495
Rheumatoid arthritis 9 | 1,191
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Hypertensive disease 8 | 292
Kidney disease 8 | 430
fibroadenoma 8 | 559
Alcoholic Intoxication, Chronic 7 | 289
Alzheimer's disease 7 | 658
Atherosclerosis 7 | 291
Bipolar Disorder 7 | 666
Coronary artery disease 7 | 268
Mental Depression 7 | 333
Orbital separation excessive 7 | 244
Osteoporosis 7 | 363
Short stature 7 | 531
active ulcerative colitis 7 | 764
interstitial lung disease 7 | 298
juvenile dermatomyositis 7 | 1,187
medulloblastoma 7 | 720
non primary Sjogren syndrome sicca 7 | 891
Breast Neoplasms 6 | 445
Cardiovascular system disease 6 | 246
Liver cancer 6 | 604
Liver disease 6 | 237
Lung Neoplasms 6 | 232
Mammary Neoplasms 6 | 425
Seizures 6 | 596
Type 2 diabetes mellitus 6 | 272
non-small cell lung carcinoma 6 | 317
pediatric high grade glioma 6 | 1,064
sonic hedgehog group medulloblastoma 6 | 467
spina bifida 6 | 1,074
Broad flat nasal bridge 5 | 236
Cognitive delay 5 | 608
Mental and motor retardation 5 | 608
Multiple myeloma 5 | 1,332
Nasal bridge wide 5 | 236
Vascular disease 5 | 319
acute quadriplegic myopathy 5 | 1,158
aldosterone-producing adenoma 5 | 665
esophageal adenocarcinoma 5 | 737
hepatocellular carcinoma 5 | 547
nephrosclerosis 5 | 333
tuberculosis and treatment for 3 months 5 | 179

Tissue

Digestive Tract 96 | 17,369
Endocrine System 96 | 18,159
Male tissues 96 | 17,142
Urinary Tract 96 | 16,678
Blood and immune system 95 | 16,909
Female tissues 95 | 17,400
Liver and Pancreas 95 | 16,750
Nervous System 95 | 16,725
Respiratory system 95 | 16,393
Skin and soft tissues 95 | 17,230
Cardiovascular System 92 | 15,192

Target Family

Non-IDG 47 | 12,091
Enzyme 18 | 4,145
Transcription Factor 11 | 1,400
GPCR 5 | 408
Transporter 5 | 473
Epigenetic 3 | 242
Kinase 3 | 634
Ion Channel 2 | 344
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48

GWAS Trait

Pulse pressure 97 | 97
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fidgetin FIGN Tbio Enzyme -1.34015 21.2 103
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
Pleckstrin homology domain-containing family J member 1 PLEKHJ1 Tbio Non-IDG 0.70 0.18 107
Src kinase-associated phosphoprotein 1 SKAP1 Tbio Enzyme -1.31527 25.2 175
Neuronal PAS domain-containing protein 2 NPAS2 Tbio Transcription Factor -1.91320 81.4 182
Neurogenic locus notch homolog protein 3 NOTCH3 Tchem Non-IDG -2.67185 458.4 499
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749
Protein FAM13A FAM13A Tbio Non-IDG -1.32713 21.6 19
Rho GTPase-activating protein 12 ARHGAP12 Tdark Enzyme -0.66875 4.90 36
Estradiol 17-beta-dehydrogenase 1 HSD17B1 Tchem Enzyme -2.36315 220.8 198