Development Level

Tbio 19 | 11,445
Tdark 4 | 6,588
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal limb morphology 1 | 13
abnormal skin appearance 1 | 3
abnormal tail morphology 1 | 25
abnormal vertebrae morphology 1 | 18
cataract 1 | 92
decreased KLRG1+ CD8 alpha bet... 1 | 2
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
increased hematocrit 1 | 46
increased kidney weight 1 | 6
increased or absent threshold ... 1 | 101
long tibia 1 | 25
short tibia 1 | 97

Disease

Asthma 23 | 385
Carcinoma 20 | 11,493
medulloblastoma, large-cell 15 | 6,241
glioblastoma 14 | 5,792
adult high grade glioma 13 | 3,801
atypical teratoid / rhabdoid tumor 13 | 5,112
Breast cancer 12 | 3,578
Kidney cancer 12 | 2,613
osteosarcoma 12 | 7,950
ovarian cancer 12 | 8,520
ependymoma 11 | 4,679
Astrocytoma, Pilocytic 10 | 3,081
group 4 medulloblastoma 9 | 1,855
lung cancer 9 | 4,740
lung carcinoma 9 | 2,843
malignant mesothelioma 9 | 3,232
oligodendroglioma 9 | 2,850
primitive neuroectodermal tumor 9 | 3,035
subependymal giant cell astrocytoma 9 | 2,287
pancreatic cancer 8 | 2,398
group 3 medulloblastoma 7 | 4,104
psoriasis 7 | 6,694
Liver cancer 6 | 604
astrocytic glioma 6 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
Bipolar Disorder 5 | 666
Multiple Sclerosis 5 | 540
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
Acquired metabolic disease 4 | 336
Intellectual disability 4 | 1,016
acute quadriplegic myopathy 4 | 1,158
colon cancer 4 | 1,478
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic carcinoma 4 | 562
Cardiomyopathies 3 | 110
Celiac disease 3 | 116
Dull intelligence 3 | 645
Endometrial cancer 3 | 311
Large intestine cancer 3 | 126
Liver Cirrhosis, Experimental 3 | 769
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Multiple myeloma 3 | 1,332
Poor school performance 3 | 645
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Short stature 3 | 531
Substance-Related Disorders 3 | 115
Waldenstrons macroglobulinemia 3 | 765
aldosterone-producing adenoma 3 | 665
esophageal adenocarcinoma 3 | 737
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
non-small cell lung cancer 3 | 2,890
Alcoholic Intoxication, Chronic 2 | 289
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Blindness 2 | 88
Byzanthine arch palate 2 | 194
Creatine phosphokinase serum increased 2 | 110
Elevated creatine kinase 2 | 110
Enophthalmos 2 | 75
Heart conduction disease 2 | 83
Melanoma 2 | 711
Microcephaly 2 | 166
Muscle hypotonia 2 | 571
Neuropathy 2 | 261
Nonsyndromic deafness 2 | 142
Parkinson's disease 2 | 392
Pick disease 2 | 1,894
Prostate cancer 2 | 175
Retinitis Pigmentosa 2 | 226
Sensorineural hearing loss 2 | 106
Small head 2 | 374
USHER SYNDROME, TYPE ID 2 | 2
Usher Syndrome, Type I 2 | 6
Usher syndrome 2 | 32
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
astrocytoma 2 | 1,146
cutaneous lupus erythematosus 2 | 1,057
gastric cancer 2 | 459
hereditary spastic paraplegia 2 | 318
mucosa-associated lymphoid tissue lymphoma 2 | 484
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 24 | 16,909
Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Skin and soft tissues 24 | 17,230
Cardiovascular System 23 | 15,192
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Urinary Tract 23 | 16,678
Respiratory system 22 | 16,393

Target Family

Non-IDG 18 | 12,091
Enzyme 4 | 4,145
Ion Channel 1 | 344
Kinase 1 | 634
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400
Transporter 1 | 473

GWAS Trait

Pulmonary function decline 27 | 27
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
CUB and sushi domain-containing protein 1 CSMD1 Tbio Non-IDG -1.68684 47.7 0
Centlein CNTLN Tbio Non-IDG -2.28518 122.3 76
E3 ISG15--protein ligase HERC5 HERC5 Tbio Enzyme -1.63055 44.5 57
Sodium/potassium/calcium exchanger 3 SLC24A3 Tbio Transporter -1.12274 13.0 86
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A PDE9A Tchem Enzyme -1.92564 78.9 151
Carboxypeptidase O CPO Tdark Enzyme -0.37892 2.01 101
Protocadherin gamma-A1 PCDHGA1 Tdark Non-IDG 0.57 0.27 131
Catenin delta-2 CTNND2 Tbio Non-IDG -1.91434 95.4 137