Development Level

Tbio 25 | 11,651
Tchem 4 | 1,388
Tclin 4 | 612
Tdark 3 | 6,593

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

increased startle reflex 3 | 112
preweaning lethality, complete... 3 | 979
abnormal locomotor activation 2 | 16
abnormal startle reflex 2 | 15
decreased body weight 2 | 161
decreased circulating iron lev... 2 | 32
decreased circulating phosphat... 2 | 27
decreased erythrocyte cell num... 2 | 62
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
enlarged spleen 2 | 41
increased blood urea nitrogen ... 2 | 48
increased circulating amylase ... 2 | 25
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal esophagus morphology 1 | 5
abnormal limb bud morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
absent lymph nodes 1 | 3
anophthalmia 1 | 33
athymia 1 | 2
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased circulating chloride... 1 | 30
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
embryonic lethality prior to t... 1 | 278
impaired pupillary reflex 1 | 26
increased body weight 1 | 25
increased or absent threshold ... 1 | 101
pallor 1 | 34

Disease

Carcinoma 29 | 11,493
Chronic obstructive pulmonary disease 21 | 184
ovarian cancer 21 | 8,520
psoriasis 18 | 6,694
osteosarcoma 16 | 7,950
lung cancer 14 | 4,740
malignant mesothelioma 14 | 3,232
medulloblastoma, large-cell 14 | 6,241
group 3 medulloblastoma 12 | 4,104
lung carcinoma 12 | 2,843
Breast cancer 11 | 3,578
Cancer 11 | 2,499
Kidney cancer 10 | 2,613
glioblastoma 10 | 5,792
invasive ductal carcinoma 10 | 2,951
atypical teratoid / rhabdoid tumor 9 | 5,112
cystic fibrosis 9 | 1,696
interstitial cystitis 9 | 2,312
Melanoma 8 | 711
Schizophrenia 8 | 1,160
ductal carcinoma in situ 8 | 1,745
ependymoma 8 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
lung adenocarcinoma 8 | 2,716
pancreatic cancer 7 | 2,398
ulcerative colitis 7 | 1,819
Pick disease 6 | 1,894
adrenocortical carcinoma 6 | 1,428
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
primary pancreatic ductal adenocarcinoma 6 | 1,109
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
Alzheimer's disease 5 | 658
Obesity 5 | 678
Rheumatoid arthritis 5 | 1,191
Skin cancer 5 | 469
adult high grade glioma 5 | 3,801
astrocytoma 5 | 1,146
breast carcinoma 5 | 1,638
chronic rhinosinusitis 5 | 512
colon cancer 5 | 1,478
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
posterior fossa group A ependymoma 5 | 468
primitive neuroectodermal tumor 5 | 3,035
Astrocytoma, Pilocytic 4 | 3,081
Multiple Sclerosis 4 | 540
Multiple myeloma 4 | 1,332
Seizures 4 | 596
aldosterone-producing adenoma 4 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
dermatomyositis 4 | 966
fibroadenoma 4 | 559
gastric carcinoma 4 | 807
group 4 medulloblastoma 4 | 1,855
nasopharyngeal carcinoma 4 | 1,058
pituitary cancer 4 | 1,972
spina bifida 4 | 1,074
Amyotrophic lateral sclerosis 3 | 451
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Cognitive delay 3 | 608
Duchenne muscular dystrophy 3 | 601
Dull intelligence 3 | 645
Endometriosis 3 | 540
Epilepsy 3 | 792
Gastroesophageal reflux disease 3 | 110
Global developmental delay 3 | 608
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mammary Neoplasms 3 | 425
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Migraine 3 | 83
Osteoporosis 3 | 363
Poor school performance 3 | 645
Stomach Neoplasms 3 | 300
Type 2 diabetes mellitus 3 | 272
acute quadriplegic myopathy 3 | 1,158
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
Atherosclerosis 2 | 291
Bilateral fifth finger clinodactyly 2 | 110
Broad flat nasal bridge 2 | 236
Curvature of little finger 2 | 110
Down syndrome 2 | 499
Endometrial cancer 2 | 311
Gamma chain deficiency 2 | 7
Glaucoma 2 | 239
Leukemia 2 | 104
Mental Depression 2 | 333
Nasal bridge wide 2 | 236
Umbilical hernia 2 | 93
esophageal adenocarcinoma 2 | 737
mucosa-associated lymphoid tissue lymphoma 2 | 484
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676

Tissue

Digestive Tract 34 | 17,369
Blood and immune system 33 | 16,909
Liver and Pancreas 33 | 16,750
Respiratory system 33 | 16,393
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678
Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Cardiovascular System 29 | 15,192

Target Family

Non-IDG 23 | 12,091
Enzyme 6 | 4,145
GPCR 2 | 408
Nuclear Receptor 2 | 48
Epigenetic 1 | 242
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

GWAS Trait

Pulmonary function (smoking in... 36 | 36
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nephronectin NPNT Tbio Non-IDG -1.54450 37.2 104
Protein patched homolog 1 PTCH1 Tbio Non-IDG -3.04637 1057.4 452
Protein-arginine deiminase type-3 PADI3 Tchem Enzyme -1.64865 41.7 53
WW domain-containing oxidoreductase WWOX Tbio Enzyme -3.61683 3311.4 251
Protein FAM13A FAM13A Tbio Non-IDG -1.32713 21.6 19
Thrombospondin type-1 domain-containing protein 4 THSD4 Tdark Non-IDG -0.62904 3.69 5
Lumican LUM Tbio Non-IDG -2.72477 535.8 237
Prolow-density lipoprotein receptor-related protein 1 LRP1 Tbio Non-IDG -2.52012 357.1 711
Integrin alpha-1 ITGA1 Tbio Non-IDG -1.97879 88.9 397
Retinoic acid receptor beta RARB Tclin Nuclear Receptor -2.51618 295.9 391