Development Level

Tbio 18 | 10,625
Tdark 4 | 7,003
Tchem 3 | 1,890
Tclin 3 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 1 | 24

IMPC Phenotype

abnormal bone mineralization 2 | 55
abnormal locomotor activation 2 | 26
abnormal startle reflex 2 | 14
decreased body weight 2 | 174
decreased circulating iron lev... 2 | 25
decreased erythrocyte cell num... 2 | 43
decreased hematocrit 2 | 25
decreased hemoglobin content 2 | 53
decreased lean body mass 2 | 195
decreased prepulse inhibition 2 | 52
increased blood urea nitrogen ... 2 | 44
increased circulating amylase ... 2 | 13
limb grasping 2 | 35
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal coat-hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal esophagus morphology 1 | 4
abnormal limb bud morphology 1 | 15
abnormal pancreas morphology 1 | 6
abnormal pericardium morpholog... 1 | 11
abnormal retinal vasculature m... 1 | 15
abnormal skin coloration 1 | 18
abnormal sleep behavior 1 | 63
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
absent lymph nodes 1 | 3
anophthalmia 1 | 20
athymia 1 | 1
cardiovascular system phenotyp... 1 | 35
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
increased body weight 1 | 42
increased startle reflex 1 | 38
pallor 1 | 13

Disease

Pulmonary function (finding) 26 | 33
Chronic obstructive pulmonary disease 21 | 147
ovarian cancer 16 | 8,491
osteosarcoma 13 | 7,933
psoriasis 13 | 6,685
malignant mesothelioma 12 | 3,163
lung cancer 10 | 4,473
lung carcinoma 10 | 2,844
Breast cancer 9 | 3,098
medulloblastoma, large-cell 9 | 6,234
Carcinoma 8 | 2,147
glioblastoma 8 | 5,572
interstitial cystitis 8 | 2,299
Cancer 7 | 2,346
group 3 medulloblastoma 7 | 2,254
invasive ductal carcinoma 7 | 2,950
ulcerative colitis 7 | 2,087
Pick disease 6 | 1,893
adrenocortical carcinoma 6 | 1,427
cystic fibrosis 6 | 1,670
ductal carcinoma in situ 6 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
lung adenocarcinoma 6 | 2,714
atypical teratoid / rhabdoid tumor 5 | 4,369
colon cancer 5 | 1,475
non-small cell lung cancer 5 | 2,798
oligodendroglioma 5 | 2,849
pancreatic cancer 5 | 2,300
primary pancreatic ductal adenocarcinoma 5 | 1,271
primitive neuroectodermal tumor 5 | 3,031
Alzheimer's disease 4 | 644
astrocytoma 4 | 1,493
atypical teratoid/rhabdoid tumor 4 | 1,095
chronic rhinosinusitis 4 | 512
dermatomyositis 4 | 966
ependymoma 4 | 2,514
fibroadenoma 4 | 557
group 4 medulloblastoma 4 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
posterior fossa group A ependymoma 4 | 1,511
posterior fossa group B ependymoma 4 | 1,530
tuberculosis 4 | 1,563
Endometriosis 3 | 535
Gastroesophageal reflux disease 3 | 37
Mammary Neoplasms 3 | 410
Migraine 3 | 79
Multiple myeloma 3 | 1,327
Obesity 3 | 616
Rheumatoid Arthritis 3 | 1,170
Schizophrenia 3 | 503
aldosterone-producing adenoma 3 | 664
breast carcinoma 3 | 1,614
diabetes mellitus 3 | 1,663
inflammatory breast cancer 3 | 404
medulloblastoma 3 | 1,524
nasopharyngeal carcinoma 3 | 1,056
pediatric high grade glioma 3 | 2,712
pilocytic astrocytoma 3 | 3,086
spina bifida 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
Acquired metabolic disease 2 | 267
Adenocarcinoma 2 | 115
Barrett's esophagus 2 | 185
Bronchitis, Chronic 2 | 9
Chronic Obstructive Airway Disease 2 | 47
Cognitive disorder 2 | 44
Common Migraine 2 | 11
Down syndrome 2 | 548
Gamma chain deficiency 2 | 7
Hypertensive disorder 2 | 58
Leukemia 2 | 88
Lung Neoplasms 2 | 171
MYELODYSPLASTIC SYNDROME 2 | 39
Migraine Disorders 2 | 26
Multiple Sclerosis 2 | 498
Osteoporosis 2 | 259
Radio-ulnar synostosis-amegakaryocytic thrombocytopenia syndrome 2 | 3
Squamous cell carcinoma 2 | 96
Stomach Neoplasms 2 | 282
Substance-Related Disorders 2 | 114
Type 2 diabetes mellitus 2 | 192
acute myeloid leukemia 2 | 785
adult high grade glioma 2 | 2,148
astrocytic glioma 2 | 2,241
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
cystic fibrosis and chronic rhinosinusitis 2 | 213
facioscapulohumeral dystrophy 2 | 286
gastric carcinoma 2 | 832
interstitial lung disease 2 | 292
mucosa-associated lymphoid tissue lymphoma 2 | 480
non diabetic and post-ischemic heart failure 2 | 200
non primary Sjogren syndrome sicca 2 | 840
permanent atrial fibrillation 2 | 44
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 674
Acne vulgaris 1 | 16
Cocaine dependence 1 | 24
Esophagitis 1 | 26
Malignant neoplasm of lung 1 | 16

Tissue

Blood and immune system 27 | 17,994
Cardiovascular System 27 | 17,957
Digestive Tract 27 | 18,472
Endocrine System 27 | 18,511
Female tissues 27 | 18,646
Liver and Pancreas 27 | 18,135
Male tissues 27 | 17,968
Nervous System 27 | 18,560
Respiratory system 27 | 17,483
Skin and soft tissues 27 | 18,114
Urinary Tract 27 | 18,443

Target Family

Non-IDG 18 | 11,969
Enzyme 5 | 4,146
GPCR 2 | 408
Ion Channel 1 | 341
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GWAS Trait

Pulmonary function (interactio... 28 | 28
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1-FVC r... 191 | 191
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 111 | 111
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1-FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WW domain-containing oxidoreductase WWOX Tbio Enzyme -3.56179 2916.0 232
Protein-arginine deiminase type-3 PADI3 Tchem Enzyme -1.62226 40.0 40
Thrombospondin type-1 domain-containing protein 4 THSD4 Tdark Non-IDG -0.50553 2.62 6
Protein FAM13A FAM13A Tbio Non-IDG -1.27565 18.4 16
Craniofacial development protein 1 CFDP1 Tbio Non-IDG -1.70925 51.8 104
Prolow-density lipoprotein receptor-related protein 1 LRP1 Tbio Non-IDG -2.48331 327.1 537
Leucine-rich repeat-containing protein C10orf11 C10orf11 Tdark Non-IDG -0.58229 3.60 6
Disintegrin and metalloproteinase domain-containing protein 19 ADAM19 Tbio Enzyme -1.56857 41.8 160
Astrotactin-2 ASTN2 Tbio Non-IDG -0.96352 9.16 73
Armadillo repeat-containing protein 2 ARMC2 Tdark Non-IDG -0.35459 1.91 9