Development Level

Tbio 8 | 11,651
Tdark 1 | 6,593

IMPC Phenotype

abnormal heart morphology 1 | 162
decreased circulating alkaline... 1 | 46
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased heart weight 1 | 62
increased monocyte cell number 1 | 63
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
short tibia 1 | 97

Disease

Carcinoma 9 | 11,493
ependymoma 7 | 4,679
ovarian cancer 7 | 8,520
Breast cancer 6 | 3,578
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
medulloblastoma, large-cell 6 | 6,241
group 3 medulloblastoma 5 | 4,104
pancreatic cancer 5 | 2,398
Kidney cancer 4 | 2,613
Pick disease 4 | 1,894
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
osteosarcoma 4 | 7,950
Astrocytoma, Pilocytic 3 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
oligodendroglioma 3 | 2,850
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 459
invasive ductal carcinoma 2 | 2,951
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
ARTHROGRYPOSIS, DISTAL, TYPE 1 1 | 6
Adenoid Cystic Carcinoma 1 | 99
Adenoma, Liver Cell 1 | 8
Atherosclerosis 1 | 291
Atopic dermatitis 1 | 952
Bipolar Disorder 1 | 666
Cafe-au-Lait Spots 1 | 37
Carcinoma, Adenoid Cystic 1 | 99
Carcinoma, Hepatocellular 1 | 228
Cardiofaciocutaneous syndrome 1 | 15
Celiac disease 1 | 116
Cervical Dystonia 1 | 26
Cocaine-Related Disorders 1 | 92
Congenital neurologic anomalies 1 | 20
Costello Syndrome 1 | 17
Dementia 1 | 175
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Distal arthrogryposis 1 | 42
Duchenne muscular dystrophy 1 | 601
Endometrial cancer 1 | 311
Episodic ataxia 1 | 22
Fuchs' endothelial dystrophy 1 | 24
Gingival fibromatosis 1 | 14
Kidney disease 1 | 430
LEOPARD syndrome 1 | 20
Large intestine cancer 1 | 126
Liver cancer 1 | 604
Liver neoplasms 1 | 130
Malaria 1 | 160
Melanoma 1 | 711
Multiple Sclerosis 1 | 540
Nervous System Malformations 1 | 10
Neurodegenerative disease 1 | 414
Neurofibromatosis 1 | 40
Noonan syndrome 1 | 34
Piebaldism 1 | 15
Polycystic ovary syndrome 1 | 360
Posterior polymorphous corneal dystrophy 1 | 19
Precancerous Conditions 1 | 80
Pulmonary valve stenosis 1 | 9
Salivary Gland Neoplasms 1 | 46
Schizophrenia 1 | 1,160
Skin cancer 1 | 469
Spondylolisthesis 1 | 22
X-linked endothelial corneal dystrophy 1 | 9
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
cystic fibrosis 1 | 1,696
cystic fibrosis and chronic rhinosinusitis 1 | 214
dermatomyositis 1 | 966
facioscapulohumeral dystrophy 1 | 288
gastric carcinoma 1 | 807
hepatocellular carcinoma 1 | 547
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
non-small cell lung cancer 1 | 2,890
pediatric high grade glioma 1 | 1,064
primary pancreatic ductal adenocarcinoma 1 | 1,109
progressive supranuclear palsy 1 | 676
sonic hedgehog group medulloblastoma 1 | 467
tuberculosis 1 | 2,010
tuberculosis and treatment for 3 months 1 | 179

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Nervous System 8 | 16,725

Target Family

Non-IDG 6 | 12,091
Enzyme 1 | 4,145
Ion Channel 1 | 344
Transporter 1 | 473

GWAS Trait

Psychosis (atypical) 9 | 9
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium leak channel non-selective protein NALCN Tbio Ion Channel -1.72377 54.1 62
Protein PRRC2A PRRC2A Tbio Non-IDG -1.93238 84.8 8
Protein FAM98B FAM98B Tdark Non-IDG 0.13 0.71 81
Collagen alpha-1(XXI) chain COL21A1 Tbio Non-IDG -0.67130 4.90 89
Beta-chimaerin CHN2 Tbio Non-IDG -1.78873 58.0 149
Sodium/potassium/calcium exchanger 3 SLC24A3 Tbio Transporter -1.12274 13.0 86
Sprouty-related, EVH1 domain-containing protein 1 SPRED1 Tbio Non-IDG -1.93963 79.1 299
E3 ubiquitin-protein ligase TRIM9 TRIM9 Tbio Enzyme -1.03221 10.8 307
Ubiquitin-conjugating enzyme E2 E2 UBE2E2 Tbio Non-IDG -1.41744 21.8 130