Development Level

Tbio 24 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

decreased fasted circulating g... 2 | 65
increased mean corpuscular hem... 2 | 96
abnormal behavior 1 | 298
abnormal locomotor behavior 1 | 24
cataract 1 | 92
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
preweaning lethality, complete... 1 | 979

Disease

psoriasis 25 | 6,694
Carcinoma 24 | 11,493
ovarian cancer 22 | 8,520
glioblastoma 18 | 5,792
osteosarcoma 18 | 7,950
lung cancer 15 | 4,740
adult high grade glioma 13 | 3,801
ependymoma 13 | 4,679
medulloblastoma, large-cell 13 | 6,241
Astrocytoma, Pilocytic 12 | 3,081
atypical teratoid / rhabdoid tumor 12 | 5,112
tuberculosis 12 | 2,010
Cancer 11 | 2,499
malignant mesothelioma 10 | 3,232
Breast cancer 9 | 3,578
Crohn's disease 9 | 321
Kidney cancer 9 | 2,613
non-small cell lung cancer 9 | 2,890
pancreatic cancer 9 | 2,398
ulcerative colitis 9 | 1,819
Psoriatic arthritis 8 | 86
diabetes mellitus 8 | 1,728
interstitial cystitis 8 | 2,312
lung carcinoma 8 | 2,843
subependymal giant cell astrocytoma 8 | 2,287
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
invasive ductal carcinoma 7 | 2,951
Multiple Sclerosis 6 | 540
Systemic lupus erythematosus 6 | 194
acute myeloid leukemia 6 | 783
acute quadriplegic myopathy 6 | 1,158
cystic fibrosis 6 | 1,696
Celiac disease 5 | 116
Rheumatoid arthritis 5 | 1,191
dermatomyositis 5 | 966
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
juvenile dermatomyositis 5 | 1,187
oligodendroglioma 5 | 2,850
primary pancreatic ductal adenocarcinoma 5 | 1,109
Arthritis 4 | 290
Asthma 4 | 385
Liver Cirrhosis, Experimental 4 | 769
Melanoma 4 | 711
Pick disease 4 | 1,894
active ulcerative colitis 4 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
esophageal adenocarcinoma 4 | 737
lung adenocarcinoma 4 | 2,716
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
spina bifida 4 | 1,074
Adenocarcinoma 3 | 122
Ankylosing spondylitis 3 | 140
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Cell Transformation, Neoplastic 3 | 97
Common variable immunodeficiency 3 | 101
Hyperkeratosis 3 | 50
Inflammation 3 | 120
Inflammatory bowel disease 3 | 151
Lung Neoplasms 3 | 232
Lung disease 3 | 142
Lupus Erythematosus, Systemic 3 | 67
Lymphoid leukemia 3 | 160
Multiple myeloma 3 | 1,332
Myocardial Infarction 3 | 151
Neoplastic Cell Transformation 3 | 89
Reperfusion Injury 3 | 86
Skin cancer 3 | 469
Spondylitis, Ankylosing 3 | 11
Stevens-Johnson syndrome 3 | 92
active Crohn's disease 3 | 922
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 807
group 4 medulloblastoma 3 | 1,855
pancreatic carcinoma 3 | 562
posterior fossa group A ependymoma 3 | 468
primary Sjogren syndrome 3 | 735
substance-related disorder 3 | 162
Alzheimer's disease 2 | 658
Brain Ischemia 2 | 110
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Hypersensitivity reaction type II disease 2 | 253
Hypertension 2 | 396
Kidney disease 2 | 430
Leishmaniasis 2 | 47
Malaria 2 | 160
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Stomach Neoplasms 2 | 300
chronic rhinosinusitis 2 | 512
medulloblastoma 2 | 720
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 32 | 16,909
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Skin and soft tissues 30 | 17,230
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Urinary Tract 29 | 16,678
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 12 | 12,091
Enzyme 11 | 4,145
Transcription Factor 6 | 1,400
Kinase 2 | 634
Ion Channel 1 | 344

GWAS Trait

Psoriasis vulgaris 32 | 32
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
NF-kappa-B inhibitor zeta NFKBIZ Tbio Non-IDG -2.14151 143.2 111
Prolyl 3-hydroxylase 2 P3H2 Tbio Enzyme -2.49306 295.2 60
Late cornified envelope protein 3A LCE3A Tdark Non-IDG -0.37436 2.16 0
Late cornified envelope protein 3B LCE3B Tbio Non-IDG -1.17734 17.9 0
Zinc finger MIZ domain-containing protein 1 ZMIZ1 Tbio Transcription Factor -1.57174 37.9 126
Adapter protein CIKS TRAF3IP2 Tbio Non-IDG -1.81845 71.6 360
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.35134 2277.5 752
Inactive phospholipase C-like protein 2 PLCL2 Tbio Enzyme -0.30556 2.11 96
Class E basic helix-loop-helix protein 40 BHLHE40 Tbio Transcription Factor -1.77841 66.6 224