Development Level

Tbio 15 | 11,445
Tchem 9 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

enlarged heart 2 | 210
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
decreased T cell number 1 | 15
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
decreased neutrophil cell numb... 1 | 42
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
enlarged testis 1 | 6
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased CD4-positive, alpha ... 1 | 4
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
male infertility 1 | 123

Disease

Carcinoma 20 | 11,493
osteosarcoma 17 | 7,950
psoriasis 13 | 6,694
Cancer 12 | 2,499
ovarian cancer 12 | 8,520
lung cancer 11 | 4,740
Rheumatoid arthritis 10 | 1,191
glioblastoma 10 | 5,792
interstitial cystitis 9 | 2,312
cutaneous lupus erythematosus 8 | 1,057
medulloblastoma, large-cell 8 | 6,241
non-small cell lung cancer 8 | 2,890
Type 1 diabetes mellitus 7 | 109
atypical teratoid / rhabdoid tumor 7 | 5,112
invasive ductal carcinoma 7 | 2,951
lung adenocarcinoma 7 | 2,716
malignant mesothelioma 7 | 3,232
ulcerative colitis 7 | 1,819
Breast cancer 6 | 3,578
Kidney cancer 6 | 2,613
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
lung carcinoma 6 | 2,843
Arthritis, Rheumatoid 5 | 174
Crohn's disease 5 | 321
Hypersensitivity reaction type II disease 5 | 253
Lupus Erythematosus, Systemic 5 | 67
Multiple Sclerosis 5 | 540
Vitiligo 5 | 73
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
pancreatic cancer 5 | 2,398
primitive neuroectodermal tumor 5 | 3,035
spina bifida 5 | 1,074
Alopecia areata 4 | 41
Astrocytoma, Pilocytic 4 | 3,081
Celiac disease 4 | 116
Common variable immunodeficiency 4 | 101
Hyperactive behavior 4 | 91
Schizophrenia 4 | 1,160
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
subependymal giant cell astrocytoma 4 | 2,287
Anemia 3 | 365
Asthma 3 | 385
Autistic Disorder 3 | 364
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Cholangitis, Sclerosing 3 | 6
Crohn Disease 3 | 45
Diabetes Mellitus, Insulin-Dependent 3 | 48
Dull intelligence 3 | 645
HIV Infections 3 | 102
Inflammatory bowel disease 3 | 151
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Lymphoid leukemia 3 | 160
Lymphoproliferative syndrome 3 | 58
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Primary biliary cirrhosis 3 | 51
Prostatic Neoplasms 3 | 495
Severe combined immunodeficiency 3 | 51
Splenomegaly 3 | 190
Stereotypic Movement Disorder 3 | 42
Vascular disease 3 | 319
active ulcerative colitis 3 | 764
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
gastric carcinoma 3 | 807
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
mucosa-associated lymphoid tissue lymphoma 3 | 484
non primary Sjogren syndrome sicca 3 | 891
pituitary cancer 3 | 1,972
primary Sjogren syndrome 3 | 735
sarcoidosis 3 | 370
tuberculosis 3 | 2,010
Aggressive behavior 2 | 75
Allergic rhinitis 2 | 94
Alzheimer's disease 2 | 658
Atopic dermatitis 2 | 952
Dermatitis, Allergic Contact 2 | 67
Epilepsy 2 | 792
Hepatomegaly 2 | 285
Kidney disease 2 | 430
Seizures 2 | 596
hepatocellular carcinoma 2 | 547
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
tuberculosis and treatment for 3 months 2 | 179
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 28 | 16,909
Digestive Tract 28 | 17,369
Male tissues 28 | 17,142
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678
Cardiovascular System 25 | 15,192
Nervous System 24 | 16,725

Target Family

Non-IDG 17 | 12,091
Enzyme 7 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

GWAS Trait

Primary sclerosing cholangitis 28 | 28
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Coiled-coil domain-containing protein 88B CCDC88B Tdark Non-IDG -0.77694 6.44 39
Membrane metallo-endopeptidase-like 1 MMEL1 Tchem Enzyme -1.49216 32.7 122
Serine/threonine-protein kinase SIK2 SIK2 Tchem Kinase -1.50719 36.5 233
Galactoside 2-alpha-L-fucosyltransferase 2 FUT2 Tbio Enzyme -3.06062 1122.9 105
Serine/threonine-protein kinase D2 PRKD2 Tchem Kinase -1.46203 23.4 417
Ubiquitin-associated and SH3 domain-containing protein A UBASH3A Tbio Non-IDG -2.35916 222.4 217
Cytokine-dependent hematopoietic cell linker CLNK Tbio Non-IDG -2.66433 449.7 64
Protein CLEC16A CLEC16A Tbio Non-IDG -1.62862 43.3 141
Hepatocyte growth factor-like protein MST1 Tbio Enzyme -2.04160 93.5 0
Interleukin-2 IL2 Tchem Non-IDG -4.37903 24027.6 1518