Development Level

Tbio 51 | 11,651
Tdark 10 | 6,593
Tchem 5 | 1,388
Tclin 5 | 612

IMPC Phenotype

preweaning lethality, complete... 4 | 979
absent pinna reflex 3 | 23
short tibia 3 | 97
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased vertical activity 2 | 208
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal nail morphology 1 | 8
abnormal neural tube closure 1 | 46
abnormal radius morphology 1 | 8
abnormal scapula morphology 1 | 3
abnormal spine curvature 1 | 9
abnormal ulna morphology 1 | 8
cataract 1 | 92
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased basophil cell number 1 | 16
decreased caudal vertebrae num... 1 | 53
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
female infertility 1 | 60
fused cornea and lens 1 | 5
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased basophil cell number 1 | 7
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating potassiu... 1 | 29
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
kyphosis 1 | 5
male infertility 1 | 123
pale yolk sac 1 | 25
persistence of hyaloid vascula... 1 | 33
shortened PQ interval 1 | 7
thrombocytopenia 1 | 56

Disease

Carcinoma 60 | 11,493
glioblastoma 34 | 5,792
medulloblastoma, large-cell 34 | 6,241
ependymoma 32 | 4,679
ovarian cancer 31 | 8,520
atypical teratoid / rhabdoid tumor 30 | 5,112
lung cancer 29 | 4,740
Astrocytoma, Pilocytic 27 | 3,081
osteosarcoma 26 | 7,950
adult high grade glioma 25 | 3,801
Kidney cancer 24 | 2,613
psoriasis 23 | 6,694
Breast cancer 22 | 3,578
group 3 medulloblastoma 22 | 4,104
primitive neuroectodermal tumor 22 | 3,035
lung carcinoma 21 | 2,843
interstitial cystitis 20 | 2,312
lung adenocarcinoma 20 | 2,716
pituitary cancer 19 | 1,972
astrocytic glioma 18 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
invasive ductal carcinoma 16 | 2,951
malignant mesothelioma 16 | 3,232
non-small cell lung cancer 16 | 2,890
oligodendroglioma 16 | 2,850
cystic fibrosis 15 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
Schizophrenia 14 | 1,160
pancreatic cancer 14 | 2,398
Cancer 13 | 2,499
subependymal giant cell astrocytoma 13 | 2,287
adrenocortical carcinoma 12 | 1,428
Pick disease 11 | 1,894
group 4 medulloblastoma 11 | 1,855
medulloblastoma 11 | 720
colon cancer 10 | 1,478
pediatric high grade glioma 10 | 1,064
Liver cancer 9 | 604
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
substance-related disorder 9 | 162
tuberculosis 9 | 2,010
ulcerative colitis 9 | 1,819
Autosomal recessive predisposition 8 | 1,442
Liver Cirrhosis, Experimental 8 | 769
diabetes mellitus 8 | 1,728
nasopharyngeal carcinoma 8 | 1,058
Bipolar Disorder 7 | 666
Chronic obstructive pulmonary disease 7 | 184
Melanoma 7 | 711
Rheumatoid arthritis 7 | 1,191
ductal carcinoma in situ 7 | 1,745
juvenile dermatomyositis 7 | 1,187
Acquired metabolic disease 6 | 336
Alzheimer's disease 6 | 658
Atopic dermatitis 6 | 952
Down syndrome 6 | 499
Polycystic ovary syndrome 6 | 360
active ulcerative colitis 6 | 764
acute myeloid leukemia 6 | 783
chronic rhinosinusitis 6 | 512
cutaneous lupus erythematosus 6 | 1,057
non-small cell lung carcinoma 6 | 317
primary pancreatic ductal adenocarcinoma 6 | 1,109
Alcoholic Intoxication, Chronic 5 | 289
Asthma 5 | 385
Autistic Disorder 5 | 364
Kidney disease 5 | 430
Lung Neoplasms 5 | 232
Neoplasm Invasiveness 5 | 161
Obesity 5 | 678
acute quadriplegic myopathy 5 | 1,158
breast carcinoma 5 | 1,638
gastric carcinoma 5 | 807
primary Sjogren syndrome 5 | 735
tuberculosis and treatment for 6 months 5 | 409
Alcohol dependence 4 | 107
Breast Neoplasms 4 | 445
Cleft Palate 4 | 271
Endometriosis 4 | 540
Epilepsy 4 | 792
Heart disease 4 | 306
Mammary Neoplasms, Experimental 4 | 154
Nicotine dependence 4 | 54
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
Skin cancer 4 | 469
Waldenstrons macroglobulinemia 4 | 765
active Crohn's disease 4 | 922
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
dermatomyositis 4 | 966
fibroadenoma 4 | 559
pancreatic carcinoma 4 | 562
periodontitis 4 | 293
progressive supranuclear palsy 4 | 676
sarcoidosis 4 | 370
spina bifida 4 | 1,074
Attention deficit hyperactivity disorder 3 | 278
esophageal adenocarcinoma 3 | 737

Tissue

Digestive Tract 70 | 17,369
Endocrine System 70 | 18,159
Female tissues 70 | 17,400
Male tissues 70 | 17,142
Skin and soft tissues 69 | 17,230
Respiratory system 68 | 16,393
Liver and Pancreas 67 | 16,750
Blood and immune system 66 | 16,909
Nervous System 66 | 16,725
Urinary Tract 66 | 16,678
Cardiovascular System 56 | 15,192

Target Family

Non-IDG 40 | 12,091
Enzyme 17 | 4,145
Ion Channel 5 | 344
Transcription Factor 5 | 1,400
GPCR 1 | 408
Kinase 1 | 634
TF/Epigenetic 1 | 38
oGPCR 1 | 421

GWAS Trait

Post bronchodilator FEV1-FVC r... 71 | 71
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
F-box/LRR-repeat protein 7 FBXL7 Tbio Non-IDG -0.80631 6.84 53
Serine/threonine-protein phosphatase 4 regulatory subunit 2 PPP4R2 Tbio Enzyme -0.78829 5.38 130
Contactin-5 CNTN5 Tbio Non-IDG -2.54880 296.6 100
Gamma-2-syntrophin SNTG2 Tbio Non-IDG -1.54819 34.8 66
Neuronal acetylcholine receptor subunit beta-4 CHRNB4 Tclin Ion Channel -1.57182 33.7 130
TOX high mobility group box family member 2 TOX2 Tbio Transcription Factor -1.29191 19.5 104
MKI67 FHA domain-interacting nucleolar phosphoprotein NIFK Tbio Non-IDG -1.91755 83.8 289
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase GCNT1 Tbio Enzyme -1.96417 93.3 191