Development Level

Tbio 29 | 10,625
Tchem 9 | 1,890
Tdark 8 | 7,003
Tclin 4 | 602

IMPC Phenotype

absent pinna reflex 2 | 21
decreased circulating serum al... 2 | 79
increased circulating alkaline... 2 | 119
short tibia 2 | 82
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal joint morphology 1 | 14
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal nail morphology 1 | 7
abnormal neural tube closure 1 | 37
abnormal radius morphology 1 | 8
abnormal scapula morphology 1 | 3
abnormal spine curvature 1 | 7
abnormal ulna morphology 1 | 8
absent heartbeat 1 | 6
decreased CD8-positive, alpha-... 1 | 26
decreased basophil cell number 1 | 11
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased cervical vertebrae n... 1 | 12
decreased circulating insulin ... 1 | 75
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
improved glucose tolerance 1 | 56
increased CD5-positive Ly6C-po... 1 | 4
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased grip strength 1 | 83
increased mean corpuscular hem... 1 | 93
increased or absent threshold ... 1 | 128
kyphosis 1 | 5
pale yolk sac 1 | 12
polydactyly 1 | 22
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
shortened PQ interval 1 | 6
thrombocytopenia 1 | 46

Disease

glioblastoma 23 | 5,572
medulloblastoma, large-cell 23 | 6,234
lung cancer 22 | 4,473
atypical teratoid / rhabdoid tumor 20 | 4,369
pilocytic astrocytoma 20 | 3,086
ovarian cancer 19 | 8,491
osteosarcoma 17 | 7,933
Breast cancer 16 | 3,098
Carcinoma 16 | 2,147
interstitial cystitis 16 | 2,299
lung adenocarcinoma 16 | 2,714
psoriasis 16 | 6,685
lung carcinoma 15 | 2,844
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
invasive ductal carcinoma 13 | 2,950
medulloblastoma 13 | 1,524
non-small cell lung cancer 13 | 2,798
pituitary cancer 13 | 1,972
primitive neuroectodermal tumor 13 | 3,031
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
oligodendroglioma 11 | 2,849
pediatric high grade glioma 11 | 2,712
posterior fossa group A ependymoma 11 | 1,511
adult high grade glioma 10 | 2,148
cystic fibrosis 10 | 1,670
malignant mesothelioma 10 | 3,163
subependymal giant cell astrocytoma 10 | 2,287
astrocytic glioma 9 | 2,241
colon cancer 9 | 1,475
Cancer 8 | 2,346
Pick disease 8 | 1,893
group 3 medulloblastoma 8 | 2,254
ulcerative colitis 8 | 2,087
Obesity 7 | 616
adrenocortical carcinoma 7 | 1,427
nasopharyngeal carcinoma 7 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
posterior fossa group B ependymoma 7 | 1,530
Alzheimer's disease 6 | 644
Asthma 6 | 349
Chronic obstructive pulmonary disease 6 | 147
Rheumatoid Arthritis 6 | 1,170
chronic rhinosinusitis 6 | 512
ductal carcinoma in situ 6 | 1,745
group 4 medulloblastoma 6 | 1,875
Atopic dermatitis 5 | 944
Chronic Obstructive Airway Disease 5 | 47
non-small cell lung carcinoma 5 | 413
pancreatic cancer 5 | 2,300
substance-related disorder 5 | 104
tuberculosis and treatment for 6 months 5 | 686
Alcohol dependence 4 | 107
Autistic Disorder 4 | 320
Epilepsy 4 | 346
IGA Glomerulonephritis 4 | 454
Lung Neoplasms 4 | 171
Nicotine dependence 4 | 53
Polycystic Ovary Syndrome 4 | 334
Schizophrenia 4 | 503
active ulcerative colitis 4 | 477
acute myeloid leukemia 4 | 785
aldosterone-producing adenoma 4 | 664
astrocytoma 4 | 1,493
cutaneous lupus erythematosus 4 | 1,056
diabetes mellitus 4 | 1,663
ependymoma 4 | 2,514
fibroadenoma 4 | 557
juvenile dermatomyositis 4 | 1,189
periodontitis 4 | 269
primary Sjogren syndrome 4 | 788
sarcoidosis 4 | 368
tuberculosis 4 | 1,563
Alcoholic Intoxication, Chronic 3 | 41
Anemia 3 | 252
Atherosclerosis 3 | 275
Bipolar Disorder 3 | 266
Cocaine dependence 3 | 24
Crohn's disease 3 | 304
Down syndrome 3 | 548
Endometriosis 3 | 535
Frontal lobe epilepsy 3 | 9
Heart disease 3 | 279
Kidney disease 3 | 397
Mammary Neoplasms 3 | 410
Melanoma 3 | 261
Neoplasm Invasiveness 3 | 127
Periodontal disease 3 | 37
Seizures 3 | 95
Waldenstrons macroglobulinemia 3 | 764
active Crohn's disease 3 | 918
acute quadriplegic myopathy 3 | 1,157
breast carcinoma 3 | 1,614
chronic lymphocytic leukemia 3 | 244
gastric carcinoma 3 | 832
primary pancreatic ductal adenocarcinoma 3 | 1,271
progressive supranuclear palsy 3 | 674
sonic hedgehog group medulloblastoma 3 | 1,482
spina bifida 3 | 1,064
tuberculosis and treatment for 3 months 3 | 327

Tissue

Digestive Tract 50 | 18,472
Female tissues 49 | 18,646
Liver and Pancreas 49 | 18,135
Male tissues 49 | 17,968
Respiratory system 49 | 17,483
Blood and immune system 48 | 17,994
Cardiovascular System 48 | 17,957
Endocrine System 48 | 18,511
Nervous System 48 | 18,560
Skin and soft tissues 48 | 18,114
Urinary Tract 48 | 18,443

Target Family

Non-IDG 27 | 11,969
Enzyme 13 | 4,146
Ion Channel 4 | 341
Transcription Factor 3 | 1,400
GPCR 1 | 408
Kinase 1 | 634
TF/Epigenetic 1 | 38

GWAS Trait

Post bronchodilator FEV1-FVC r... 50 | 50
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1-FVC r... 191 | 191
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 111 | 111
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.29669 19.6 50
BTB/POZ domain-containing protein 9 BTBD9 Tbio Non-IDG -1.30579 21.1 87
Neuronal acetylcholine receptor subunit beta-4 CHRNB4 Tclin Ion Channel -1.54794 32.2 109
Gamma-2-syntrophin SNTG2 Tbio Non-IDG -1.54366 34.4 64
Zinc finger protein basonuclin-2 BNC2 Tbio Transcription Factor -1.43318 28.0 57
Glutamate decarboxylase 1 GAD1 Tchem Enzyme -2.95198 860.3 465
Myeloperoxidase MPO Tchem Enzyme -3.48500 2949.2 1046
Complement factor I CFI Tbio Non-IDG -2.46470 268.2 287
C-C motif chemokine 28 CCL28 Tbio Non-IDG -2.19589 130.9 158
Aminopeptidase B RNPEP Tchem Enzyme -2.87108 730.0 113