Development Level

Tbio 205 | 11,445
Tdark 61 | 6,588
Tchem 25 | 1,598
Tclin 17 | 613

Collection

Ion Channel: IDG Consortium (T... 4 | 99
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 14 | 979
abnormal bone structure 13 | 187
preweaning lethality, incomple... 9 | 499
increased startle reflex 8 | 112
embryonic lethality prior to t... 7 | 278
decreased lean body mass 6 | 135
decreased total body fat amoun... 6 | 207
increased total body fat amoun... 6 | 134
abnormal behavior 5 | 298
abnormal embryo size 5 | 220
decreased body weight 5 | 161
decreased bone mineral content 5 | 151
decreased lymphocyte cell numb... 5 | 83
impaired glucose tolerance 5 | 75
increased lean body mass 5 | 172
short tibia 5 | 97
decreased circulating glucose ... 4 | 126
increased heart weight 4 | 62
male infertility 4 | 123
abnormal coat-hair pigmentatio... 3 | 64
abnormal neural tube closure 3 | 46
abnormal retina morphology 3 | 71
decreased body length 3 | 101
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased fasted circulating g... 3 | 65
decreased grip strength 3 | 116
decreased heart left ventricle... 3 | 28
decreased mean corpuscular hem... 3 | 31
decreased neutrophil cell numb... 3 | 42
decreased red blood cell distr... 3 | 41
decreased vertical activity 3 | 208
embryonic growth retardation 3 | 106
embryonic lethality prior to o... 3 | 239
improved glucose tolerance 3 | 79
increased blood urea nitrogen ... 3 | 48
increased circulating HDL chol... 3 | 80
increased circulating alkaline... 3 | 122
increased fasted circulating g... 3 | 76
increased hematocrit 3 | 46
increased prepulse inhibition 3 | 32
tremors 3 | 39
abnormal behavioral response t... 2 | 66
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal locomotor behavior 2 | 24
abnormal midbrain development 2 | 20
absent pinna reflex 2 | 23
cardiovascular system phenotyp... 2 | 36
decreased blood urea nitrogen ... 2 | 51
decreased circulating alkaline... 2 | 46
decreased circulating aspartat... 2 | 34
decreased circulating insulin ... 2 | 76
decreased pulmonary respirator... 2 | 5
enlarged heart 2 | 210
enlarged stomach 2 | 2
female infertility 2 | 60
hyperactivity 2 | 148
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
increased red blood cell distr... 2 | 34
increased thermal nociceptive ... 2 | 9
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
small superior vagus ganglion 2 | 74
small thymus 2 | 16
thin ventricular wall 2 | 24
thrombocytopenia 2 | 56
trunk curl 2 | 16
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal heart left ventricle ... 1 | 16
abnormal liver morphology 1 | 17
abnormal neural tube morpholog... 1 | 12
abnormal seminal vesicle morph... 1 | 114
abnormal vibrissa morphology 1 | 25
corneal opacity 1 | 32
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating serum al... 1 | 82
enlarged ovary 1 | 2
enlarged spleen 1 | 41
increased body weight 1 | 25
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased monocyte cell number 1 | 63
iris synechia 1 | 3
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
small testis 1 | 58

Disease

Carcinoma 236 | 11,493
ovarian cancer 143 | 8,520
medulloblastoma, large-cell 140 | 6,241
glioblastoma 133 | 5,792
atypical teratoid / rhabdoid tumor 131 | 5,112
osteosarcoma 121 | 7,950
ependymoma 115 | 4,679
psoriasis 112 | 6,694
adult high grade glioma 98 | 3,801
lung cancer 93 | 4,740
Kidney cancer 91 | 2,613
Astrocytoma, Pilocytic 89 | 3,081
lung carcinoma 88 | 2,843
Breast cancer 87 | 3,578
group 3 medulloblastoma 84 | 4,104
oligodendroglioma 79 | 2,850
primitive neuroectodermal tumor 74 | 3,035
astrocytic glioma 72 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 65 | 2,955
interstitial cystitis 64 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 63 | 3,291
invasive ductal carcinoma 63 | 2,951
non-small cell lung cancer 62 | 2,890
pituitary cancer 62 | 1,972
intraductal papillary-mucinous carcinoma (IPMC) 60 | 2,989
pancreatic cancer 59 | 2,398
malignant mesothelioma 58 | 3,232
lung adenocarcinoma 54 | 2,716
Pick disease 52 | 1,894
Cancer 51 | 2,499
cystic fibrosis 48 | 1,696
ductal carcinoma in situ 47 | 1,745
group 4 medulloblastoma 47 | 1,855
subependymal giant cell astrocytoma 45 | 2,287
tuberculosis 42 | 2,010
ulcerative colitis 40 | 1,819
Schizophrenia 37 | 1,160
breast carcinoma 37 | 1,638
colon cancer 36 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 36 | 1,962
adrenocortical carcinoma 34 | 1,428
Autosomal recessive predisposition 33 | 1,442
Melanoma 33 | 711
Rheumatoid arthritis 33 | 1,191
Liver cancer 31 | 604
astrocytoma 28 | 1,146
cutaneous lupus erythematosus 27 | 1,057
Skin cancer 26 | 469
Bipolar Disorder 25 | 666
Intellectual disability 22 | 1,016
Liver Cirrhosis, Experimental 22 | 769
Obesity 22 | 678
nasopharyngeal carcinoma 22 | 1,058
non primary Sjogren syndrome sicca 22 | 891
Epilepsy 20 | 792
acute quadriplegic myopathy 20 | 1,158
aldosterone-producing adenoma 20 | 665
juvenile dermatomyositis 20 | 1,187
Atopic dermatitis 19 | 952
diabetes mellitus 19 | 1,728
pediatric high grade glioma 19 | 1,064
substance-related disorder 19 | 162
Acquired metabolic disease 18 | 336
Alzheimer's disease 18 | 658
dermatomyositis 18 | 966
esophageal adenocarcinoma 18 | 737
medulloblastoma 18 | 720
spina bifida 18 | 1,074
Mental Depression 17 | 333
Type 2 diabetes mellitus 17 | 272
acute myeloid leukemia 17 | 783
fibroadenoma 17 | 559
Alcoholic Intoxication, Chronic 16 | 289
Chronic obstructive pulmonary disease 16 | 184
Depressive disorder 16 | 409
Dull intelligence 16 | 645
Endometrial cancer 16 | 311
Low intelligence 16 | 645
Mental Retardation 16 | 645
Mental deficiency 16 | 645
Multiple myeloma 16 | 1,332
Polycystic ovary syndrome 16 | 360
Poor school performance 16 | 645
Seizures 16 | 596
primary pancreatic ductal adenocarcinoma 16 | 1,109
Autistic Disorder 15 | 364
Parkinson's disease 15 | 392
non-small cell lung carcinoma 15 | 317
Short stature 14 | 531
active Crohn's disease 14 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
gastric carcinoma 14 | 807
pancreatic carcinoma 14 | 562
Cognitive delay 13 | 608
Endometriosis 13 | 540
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
Muscle hypotonia 13 | 571
active ulcerative colitis 13 | 764
sonic hedgehog group medulloblastoma 13 | 467

Tissue

Endocrine System 296 | 18,159
Female tissues 286 | 17,400
Digestive Tract 282 | 17,369
Male tissues 281 | 17,142
Skin and soft tissues 279 | 17,230
Urinary Tract 279 | 16,678
Liver and Pancreas 276 | 16,750
Nervous System 274 | 16,725
Blood and immune system 273 | 16,909
Respiratory system 269 | 16,393
Cardiovascular System 243 | 15,192

Target Family

Non-IDG 193 | 12,091
Enzyme 61 | 4,145
Ion Channel 17 | 344
Transcription Factor 12 | 1,400
Kinase 8 | 634
GPCR 6 | 408
Transporter 5 | 473
Nuclear Receptor 3 | 48
TF/Epigenetic 2 | 38
Epigenetic 1 | 242

GWAS Trait

Post bronchodilator FEV1-FVC r... 308 | 308
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cysteine-rich hydrophobic domain-containing protein 2 CHIC2 Tbio Non-IDG -2.12710 132.1 97
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Peroxisomal membrane protein 4 PXMP4 Tdark Non-IDG -0.51334 4.00 99
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
Sarcosine dehydrogenase, mitochondrial SARDH Tbio Enzyme -1.78290 56.5 35
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.08587 12.0 153
Neural retina-specific leucine zipper protein NRL Tbio Transcription Factor -2.46080 279.4 74
Glypican-6 GPC6 Tbio Non-IDG -1.33560 21.9 125
Signal-induced proliferation-associated 1-like protein 1 SIPA1L1 Tbio Non-IDG -0.56258 5.05 40