Development Level

Tbio 32 | 11,651
Tdark 16 | 6,593
Tclin 5 | 612
Tchem 3 | 1,388

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
decreased vertical activity 2 | 208
abnormal adrenal gland morphol... 1 | 1
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal epididymis morphology 1 | 42
abnormal nail morphology 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal thymus morphology 1 | 7
absent pinna reflex 1 | 23
absent startle reflex 1 | 24
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
enlarged epididymis 1 | 31
enlarged heart 1 | 210
increased fasted circulating g... 1 | 76
increased or absent threshold ... 1 | 101
male infertility 1 | 123
short tibia 1 | 97
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small thymus 1 | 16

Disease

Carcinoma 44 | 11,493
medulloblastoma, large-cell 27 | 6,241
atypical teratoid / rhabdoid tumor 24 | 5,112
ependymoma 24 | 4,679
glioblastoma 22 | 5,792
Kidney cancer 21 | 2,613
psoriasis 21 | 6,694
lung carcinoma 20 | 2,843
ovarian cancer 20 | 8,520
lung cancer 19 | 4,740
osteosarcoma 19 | 7,950
adult high grade glioma 18 | 3,801
group 3 medulloblastoma 17 | 4,104
oligodendroglioma 17 | 2,850
Breast cancer 15 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
subependymal giant cell astrocytoma 15 | 2,287
primitive neuroectodermal tumor 14 | 3,035
astrocytic glioma 13 | 2,597
lung adenocarcinoma 13 | 2,716
Astrocytoma, Pilocytic 12 | 3,081
pituitary cancer 12 | 1,972
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
pancreatic cancer 11 | 2,398
Liver cancer 10 | 604
Pick disease 10 | 1,894
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
Melanoma 9 | 711
Schizophrenia 9 | 1,160
colon cancer 9 | 1,478
group 4 medulloblastoma 9 | 1,855
invasive ductal carcinoma 9 | 2,951
ulcerative colitis 9 | 1,819
Skin cancer 8 | 469
acute quadriplegic myopathy 8 | 1,158
malignant mesothelioma 8 | 3,232
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
juvenile dermatomyositis 7 | 1,187
non-small cell lung cancer 7 | 2,890
Atopic dermatitis 6 | 952
ductal carcinoma in situ 6 | 1,745
Attention deficit hyperactivity disorder 5 | 278
Autistic Disorder 5 | 364
Chronic obstructive pulmonary disease 5 | 184
Duchenne muscular dystrophy 5 | 601
Endometrial cancer 5 | 311
Epilepsy 5 | 792
Liver Cirrhosis, Experimental 5 | 769
breast carcinoma 5 | 1,638
chronic rhinosinusitis 5 | 512
cutaneous lupus erythematosus 5 | 1,057
cystic fibrosis 5 | 1,696
fibroadenoma 5 | 559
interstitial cystitis 5 | 2,312
nasopharyngeal carcinoma 5 | 1,058
primary Sjogren syndrome 5 | 735
Alzheimer's disease 4 | 658
Autism Spectrum Disorders 4 | 75
Autism spectrum disorder 4 | 101
Bipolar Disorder 4 | 666
Cancer 4 | 2,499
Endometriosis 4 | 540
Intellectual disability 4 | 1,016
Mental Depression 4 | 333
Parkinson's disease 4 | 392
active Crohn's disease 4 | 922
adrenocortical carcinoma 4 | 1,428
aldosterone-producing adenoma 4 | 665
medulloblastoma 4 | 720
mucosa-associated lymphoid tissue lymphoma 4 | 484
substance-related disorder 4 | 162
Amyotrophic lateral sclerosis 3 | 451
Asthma 3 | 385
Autosomal recessive predisposition 3 | 1,442
DOID:2627 3 | 94
Dull intelligence 3 | 645
Low intelligence 3 | 645
Major Depressive Disorder 3 | 301
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Multiple Sclerosis 3 | 540
Nicotine dependence 3 | 54
Osteoporosis 3 | 363
Poor school performance 3 | 645
Rheumatoid arthritis 3 | 1,191
Short stature 3 | 531
Small head 3 | 374
Type 2 diabetes mellitus 3 | 272
Vascular disease 3 | 319
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
gastric carcinoma 3 | 807
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109
sarcoidosis 3 | 370
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
Depressive disorder 2 | 409

Tissue

Endocrine System 55 | 18,159
Skin and soft tissues 55 | 17,230
Digestive Tract 54 | 17,369
Female tissues 54 | 17,400
Liver and Pancreas 54 | 16,750
Male tissues 54 | 17,142
Blood and immune system 52 | 16,909
Nervous System 52 | 16,725
Urinary Tract 52 | 16,678
Respiratory system 51 | 16,393
Cardiovascular System 49 | 15,192

Target Family

Non-IDG 36 | 12,091
Enzyme 8 | 4,145
Ion Channel 6 | 344
GPCR 2 | 408
Transcription Factor 2 | 1,400
Kinase 1 | 634
Transporter 1 | 473

GWAS Trait

Post bronchodilator FEV1 in CO... 56 | 56
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Oxidation resistance protein 1 OXR1 Tbio Non-IDG -1.67505 49.4 144
Sperm flagellar protein 2 SPEF2 Tdark Non-IDG -1.20840 16.3 33
RNA-binding motif, single-stranded-interacting protein 3 RBMS3 Tbio Non-IDG -0.93602 12.0 95
Dipeptidyl aminopeptidase-like protein 6 DPP6 Tbio Enzyme -2.06587 114.8 131
Gamma-2-syntrophin SNTG2 Tbio Non-IDG -1.54819 34.8 66
Actin-binding LIM protein 2 ABLIM2 Tdark Non-IDG -0.15127 1.35 26
Prolactin receptor PRLR Tbio Non-IDG -2.77379 616.6 494
G-protein coupled receptor 98 ADGRV1 Tbio GPCR -2.51228 316.6 64
Leucine rich adaptor protein 1-like LURAP1L Tdark Non-IDG 0.48 0.00000 72