Development Level

Tbio 67 | 10,625
Tchem 21 | 1,890
Tdark 17 | 7,003
Tclin 7 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

decreased total body fat amoun... 4 | 186
decreased body weight 3 | 174
decreased circulating HDL chol... 3 | 77
decreased circulating glucose ... 3 | 121
preweaning lethality, complete... 3 | 633
preweaning lethality, incomple... 3 | 260
abnormal gait 2 | 51
decreased circulating free fat... 2 | 39
decreased lean body mass 2 | 195
impaired glucose tolerance 2 | 52
increased circulating alkaline... 2 | 119
increased circulating sodium l... 2 | 71
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
abnormal QRS complex 1 | 25
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal femur morphology 1 | 14
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal spleen morphology 1 | 36
cardiovascular system phenotyp... 1 | 35
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 27
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating insulin ... 1 | 75
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased exploration in new e... 1 | 9
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
dilated heart left ventricle 1 | 10
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
head bobbing 1 | 3
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired righting response 1 | 19
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating amylase ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating magnesiu... 1 | 10
increased fasted circulating g... 1 | 68
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
short tail 1 | 4
thrombocytosis 1 | 23

Disease

glioblastoma 58 | 5,572
medulloblastoma, large-cell 58 | 6,234
ovarian cancer 52 | 8,492
atypical teratoid / rhabdoid tumor 49 | 4,369
psoriasis 48 | 6,685
osteosarcoma 47 | 7,933
lung cancer 43 | 4,473
primitive neuroectodermal tumor 38 | 3,031
Carcinoma 35 | 2,147
pilocytic astrocytoma 33 | 3,086
oligodendroglioma 32 | 2,849
Breast cancer 31 | 3,099
pediatric high grade glioma 31 | 2,712
Pick disease 29 | 1,893
malignant mesothelioma 29 | 3,163
lung carcinoma 28 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,956
subependymal giant cell astrocytoma 26 | 2,287
invasive ductal carcinoma 25 | 2,950
lung adenocarcinoma 24 | 2,714
non-small cell lung cancer 24 | 2,798
astrocytic glioma 23 | 2,241
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
ductal carcinoma in situ 22 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,289
pituitary cancer 22 | 1,972
ependymoma 21 | 2,514
cystic fibrosis 20 | 1,670
group 4 medulloblastoma 20 | 1,875
interstitial cystitis 20 | 2,299
group 3 medulloblastoma 18 | 2,254
ulcerative colitis 17 | 2,087
adult high grade glioma 16 | 2,148
posterior fossa group A ependymoma 16 | 1,511
medulloblastoma 15 | 1,524
pancreatic cancer 15 | 2,300
Cancer 14 | 2,346
Chronic obstructive pulmonary disease 14 | 147
astrocytoma 14 | 1,493
posterior fossa group B ependymoma 13 | 1,530
primary pancreatic ductal adenocarcinoma 13 | 1,271
sonic hedgehog group medulloblastoma 13 | 1,482
Rheumatoid Arthritis 12 | 1,171
juvenile dermatomyositis 12 | 1,189
Atopic dermatitis 11 | 944
colon cancer 11 | 1,475
substance-related disorder 11 | 105
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
spina bifida 10 | 1,064
Chronic Obstructive Airway Disease 9 | 47
Schizophrenia 9 | 503
acute quadriplegic myopathy 9 | 1,157
breast carcinoma 9 | 1,614
diabetes mellitus 9 | 1,663
primary Sjogren syndrome 9 | 789
Obesity 8 | 616
active Crohn's disease 8 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
cutaneous lupus erythematosus 8 | 1,056
gastric carcinoma 8 | 832
nasopharyngeal carcinoma 8 | 1,056
Lung Neoplasms 7 | 171
Parkinson's disease 7 | 364
aldosterone-producing adenoma 7 | 664
Asthma 6 | 349
Colorectal Neoplasms 6 | 217
Duchenne muscular dystrophy 6 | 602
Multiple myeloma 6 | 1,328
Nicotine dependence 6 | 53
acute myeloid leukemia 6 | 785
atypical teratoid/rhabdoid tumor 6 | 1,095
dermatomyositis 6 | 967
non-small cell lung carcinoma 6 | 413
tuberculosis 6 | 1,563
Alzheimer's disease 5 | 644
Attention deficit hyperactivity disorder 5 | 156
IGA Glomerulonephritis 5 | 454
Intellectual disability 5 | 573
Melanoma 5 | 261
Prostatic Neoplasms 5 | 471
Waldenstrons macroglobulinemia 5 | 765
chronic rhinosinusitis 5 | 512
fibroadenoma 5 | 557
interstitial lung disease 5 | 292
nephrosclerosis 5 | 329
periodontitis 5 | 269
progressive supranuclear palsy 5 | 674
tuberculosis and treatment for 6 months 5 | 686
Acquired metabolic disease 4 | 267
Amyotrophic Lateral Sclerosis 4 | 432
Epilepsy 4 | 346
Glaucoma 4 | 135
Heart disease 4 | 279
Neuropathy 4 | 210
Peripheral Neuropathy 4 | 303
Polycystic Ovary Syndrome 4 | 335
Seizures 4 | 95
adrenocortical carcinoma 4 | 1,427
cystic fibrosis and chronic rhinosinusitis 4 | 213
esophageal adenocarcinoma 4 | 737

Tissue

Female tissues 111 | 18,647
Endocrine System 110 | 18,512
Nervous System 110 | 18,561
Urinary Tract 110 | 18,444
Digestive Tract 109 | 18,473
Liver and Pancreas 109 | 18,136
Skin and soft tissues 109 | 18,115
Blood and immune system 108 | 17,995
Cardiovascular System 108 | 17,958
Male tissues 108 | 17,969
Respiratory system 106 | 17,484

Target Family

Non-IDG 66 | 11,969
Enzyme 25 | 4,146
Ion Channel 7 | 341
Kinase 5 | 634
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
GPCR 2 | 408
Nuclear Receptor 1 | 48
Transporter 1 | 473

GWAS Trait

Post bronchodilator FEV1 112 | 112
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1/FVC r... 192 | 192
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1/FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Roundabout homolog 2 ROBO2 Tbio Non-IDG -1.86221 68.8 144
Transient receptor potential cation channel subfamily M member 3 TRPM3 Tbio Ion Channel -2.12218 123.9 117
Tetratricopeptide repeat protein 6 TTC6 Tdark Non-IDG 0.27 0.57 52
BMP-binding endothelial regulator protein BMPER Tbio Non-IDG -2.49013 302.5 105
Aryl hydrocarbon receptor nuclear translocator 2 ARNT2 Tbio Transcription Factor -1.68074 53.0 179
Calcium and integrin-binding family member 4 CIB4 Tbio Non-IDG -0.42752 2.59 80
5-hydroxytryptamine receptor 1F HTR1F Tchem GPCR -2.37415 233.4 123
Neuronal acetylcholine receptor subunit beta-4 CHRNB4 Tclin Ion Channel -1.54794 32.2 109
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.35391 28.8 85
Junctophilin-3 JPH3 Tbio Non-IDG -1.48161 31.3 143