Development Level

Tbio 156 | 11,445
Tdark 35 | 6,588
Tchem 20 | 1,598
Tclin 16 | 613

Collection

Kinase: IDG Consortium (Target... 3 | 125

IMPC Phenotype

preweaning lethality, complete... 14 | 979
preweaning lethality, incomple... 8 | 499
increased lean body mass 6 | 172
increased mean corpuscular hem... 5 | 96
abnormal embryo size 4 | 220
abnormal lens morphology 4 | 81
decreased body weight 4 | 161
decreased bone mineral density 4 | 126
decreased erythrocyte cell num... 4 | 62
improved glucose tolerance 4 | 79
abnormal startle reflex 3 | 15
cataract 3 | 92
decreased caudal vertebrae num... 3 | 53
decreased prepulse inhibition 3 | 82
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
increased bone mineral content 3 | 108
increased startle reflex 3 | 112
male infertility 3 | 123
vertebral transformation 3 | 12
abnormal bone structure 2 | 187
abnormal cornea morphology 2 | 31
abnormal locomotor activation 2 | 16
abnormal snout morphology 2 | 23
corneal opacity 2 | 32
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased grip strength 2 | 116
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased mean corpuscular vol... 2 | 79
decreased vertical activity 2 | 208
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased circulating free fat... 2 | 20
increased circulating iron lev... 2 | 30
increased circulating total pr... 2 | 28
increased lymphocyte cell numb... 2 | 32
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
abnormal behavioral response t... 1 | 66
abnormal cranium morphology 1 | 36
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
abnormal posture 1 | 2
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
abnormal vitreous body morphol... 1 | 10
absent pinna reflex 1 | 23
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased neutrophil cell numb... 1 | 42
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
enlarged kidney 1 | 14
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
long tibia 1 | 25
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97

Disease

Carcinoma 158 | 11,493
ovarian cancer 124 | 8,520
osteosarcoma 118 | 7,950
medulloblastoma, large-cell 106 | 6,241
glioblastoma 96 | 5,792
psoriasis 91 | 6,694
atypical teratoid / rhabdoid tumor 82 | 5,112
lung cancer 78 | 4,740
ependymoma 66 | 4,679
Cancer 64 | 2,499
group 3 medulloblastoma 63 | 4,104
Breast cancer 59 | 3,578
non-small cell lung cancer 56 | 2,890
invasive ductal carcinoma 55 | 2,951
malignant mesothelioma 54 | 3,232
primitive neuroectodermal tumor 54 | 3,035
adult high grade glioma 53 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 52 | 3,291
Astrocytoma, Pilocytic 51 | 3,081
lung carcinoma 49 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 48 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 47 | 2,955
subependymal giant cell astrocytoma 43 | 2,287
oligodendroglioma 42 | 2,850
Kidney cancer 40 | 2,613
lung adenocarcinoma 38 | 2,716
tuberculosis 38 | 2,010
pancreatic cancer 37 | 2,398
interstitial cystitis 36 | 2,312
cystic fibrosis 35 | 1,696
breast carcinoma 33 | 1,638
astrocytic glioma 32 | 2,597
pituitary cancer 32 | 1,972
ulcerative colitis 31 | 1,819
ductal carcinoma in situ 30 | 1,745
diabetes mellitus 28 | 1,728
group 4 medulloblastoma 28 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,962
adrenocortical carcinoma 26 | 1,428
pediatric high grade glioma 26 | 1,064
Pick disease 25 | 1,894
Rheumatoid arthritis 24 | 1,191
acute quadriplegic myopathy 24 | 1,158
colon cancer 23 | 1,478
spina bifida 23 | 1,074
astrocytoma 22 | 1,146
primary pancreatic ductal adenocarcinoma 21 | 1,109
Multiple myeloma 20 | 1,332
Schizophrenia 20 | 1,160
juvenile dermatomyositis 19 | 1,187
gastric carcinoma 18 | 807
primary Sjogren syndrome 18 | 735
Liver cancer 17 | 604
active ulcerative colitis 17 | 764
cutaneous lupus erythematosus 16 | 1,057
Autosomal recessive predisposition 15 | 1,442
acute myeloid leukemia 15 | 783
Alzheimer's disease 14 | 658
Breast Neoplasms 14 | 445
Melanoma 14 | 711
Prostatic Neoplasms 14 | 495
Waldenstrons macroglobulinemia 14 | 765
active Crohn's disease 14 | 922
esophageal adenocarcinoma 14 | 737
Crohn's disease 13 | 321
Liver Cirrhosis, Experimental 13 | 769
Mammary Neoplasms 13 | 425
Anemia 12 | 365
Kidney disease 12 | 430
hepatocellular carcinoma 12 | 547
medulloblastoma 12 | 720
Duchenne muscular dystrophy 11 | 601
Intellectual disability 11 | 1,016
Obesity 11 | 678
Osteoporosis 11 | 363
Thrombocytopenia 11 | 197
Vascular disease 11 | 319
aldosterone-producing adenoma 11 | 665
dermatomyositis 11 | 966
Amyotrophic lateral sclerosis 10 | 451
Atopic dermatitis 10 | 952
Colorectal Neoplasms 10 | 243
Diabetes Mellitus, Type 2 10 | 142
Epilepsy 10 | 792
Lymphoid leukemia 10 | 160
Multiple Sclerosis 10 | 540
Splenomegaly 10 | 190
chronic rhinosinusitis 10 | 512
nasopharyngeal carcinoma 10 | 1,058
Coronary artery disease 9 | 268
Diabetes Mellitus, Non-Insulin-Dependent 9 | 145
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
Short stature 9 | 531
Stomach Neoplasms 9 | 300
Type 2 diabetes mellitus 9 | 272
Unipolar Depression 9 | 250

Tissue

Endocrine System 218 | 18,159
Digestive Tract 216 | 17,369
Female tissues 216 | 17,400
Blood and immune system 215 | 16,909
Male tissues 214 | 17,142
Liver and Pancreas 213 | 16,750
Skin and soft tissues 211 | 17,230
Urinary Tract 210 | 16,678
Nervous System 209 | 16,725
Respiratory system 207 | 16,393
Cardiovascular System 202 | 15,192

Target Family

Non-IDG 125 | 12,091
Enzyme 48 | 4,145
Transcription Factor 25 | 1,400
Kinase 15 | 634
Epigenetic 4 | 242
Transporter 4 | 473
GPCR 2 | 408
Ion Channel 2 | 344
TF/Epigenetic 2 | 38

GWAS Trait

Plateletcrit 227 | 227
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombopoietin THPO Tbio Non-IDG -3.23551 1632.3 440
G patch domain-containing protein 8 GPATCH8 Tbio Non-IDG -0.13830 1.47 20
Solute carrier family 45 member 4 SLC45A4 Tdark Transporter 0.30 0.50 12
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Insulin-like growth factor 2 mRNA-binding protein 2 IGF2BP2 Tbio Non-IDG -1.77792 57.3 400
Cytochrome P450 26A1 CYP26A1 Tchem Enzyme -2.44772 290.1 197
Zinc finger protein ZFPM2 ZFPM2 Tbio Transcription Factor -1.78912 62.9 93
Friend leukemia integration 1 transcription factor FLI1 Tbio Transcription Factor -1.82504 66.8 454
GTP:AMP phosphotransferase AK3, mitochondrial AK3 Tbio Kinase -1.37969 23.5 249