Development Level

Tbio 5 | 10,625
Tdark 5 | 7,003
Tchem 4 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

improved glucose tolerance 2 | 56
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal seminal vesicle morph... 1 | 47
abnormal testis morphology 1 | 30
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased brain size 1 | 4
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased neutrophil cell numb... 1 | 37
hypoactivity 1 | 89
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased sacral vertebrae num... 1 | 62
mydriasis 1 | 9
no abnormal phenotype detected 1 | 3
preweaning lethality, incomple... 1 | 260
small heart 1 | 8
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
small stomach 1 | 3
small testis 1 | 37
small thymus 1 | 11
vertebral transformation 1 | 12

Disease

medulloblastoma, large-cell 8 | 6,234
atypical teratoid / rhabdoid tumor 6 | 4,369
ependymoma 5 | 2,514
glioblastoma 5 | 5,572
malignant mesothelioma 5 | 3,162
oligodendroglioma 5 | 2,849
ovarian cancer 5 | 8,484
psoriasis 5 | 6,685
Rheumatoid Arthritis 4 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
lung cancer 4 | 4,466
osteosarcoma 4 | 7,933
pituitary cancer 4 | 1,972
spina bifida 4 | 1,064
Breast cancer 3 | 3,094
Carcinoma 3 | 2,147
Obesity 3 | 616
Pick disease 3 | 1,893
astrocytic glioma 3 | 2,241
diabetes mellitus 3 | 1,663
primitive neuroectodermal tumor 3 | 3,031
Acquired metabolic disease 2 | 267
Arthritis 2 | 248
Colorectal Neoplasms 2 | 217
Metabolic syndrome X 2 | 155
adult high grade glioma 2 | 2,148
breast carcinoma 2 | 1,614
cystic fibrosis 2 | 1,665
gastric cancer 2 | 430
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
invasive ductal carcinoma 2 | 2,950
juvenile dermatomyositis 2 | 1,189
lung carcinoma 2 | 2,844
medulloblastoma 2 | 1,524
non-small cell lung cancer 2 | 2,798
pancreatic cancer 2 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
pediatric high grade glioma 2 | 2,712
posterior fossa group B ependymoma 2 | 1,530
sonic hedgehog group medulloblastoma 2 | 1,482
Acquired immunodeficiency syndrome 1 | 164
Adenoid Cystic Carcinoma 1 | 99
Ankylosing spondylitis 1 | 138
Atopic dermatitis 1 | 944
Autistic Disorder 1 | 320
Autosomal dominant cerebellar ataxia 1 | 34
Behcet's disease 1 | 74
Cancer 1 | 2,346
Cannabis dependence 1 | 18
Cardiovascular system disease 1 | 194
Crohn Disease 1 | 97
Crohn's disease 1 | 304
Epilepsy 1 | 346
Fibrinogen Adverse Event 1 | 20
Gastrointestinal system disease 1 | 50
Heart disease 1 | 279
Hemolytic anemia 1 | 66
Huntington's disease 1 | 72
Hypersensitivity reaction type II disease 1 | 235
IGA Glomerulonephritis 1 | 454
Inflammatory Bowel Diseases 1 | 87
Inflammatory dermatosis 1 | 38
Juvenile arthritis 1 | 124
Juvenile rheumatoid arthritis 1 | 104
Laryngeal squamous cell carcinoma 1 | 6
Leprosy 1 | 77
Lipid metabolism disorder 1 | 102
Lipoidosis 1 | 19
Neurodegenerative disease 1 | 383
Osteoporosis 1 | 257
Persistent hyperplastic primary vitreous 1 | 20
Platelet mean volume finding 1 | 31
Psoriatic arthritis 1 | 83
Renal Cell Carcinoma 1 | 199
Spinocerebellar ataxia type 2 1 | 19
Stomach Neoplasms 1 | 282
Thyroid cancer 1 | 25
Type 2 diabetes mellitus 1 | 189
active Crohn's disease 1 | 918
active ulcerative colitis 1 | 477
acute myeloid leukemia 1 | 780
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
astrocytoma 1 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
gastric carcinoma 1 | 832
glioblastoma multiforme 1 | 347
hepatocellular carcinoma 1 | 532
interstitial cystitis 1 | 2,299
interstitial lung disease 1 | 291
lung adenocarcinoma 1 | 2,713
non-small cell lung carcinoma 1 | 413
pancreatic carcinoma 1 | 567
periodontitis 1 | 269
pilocytic astrocytoma 1 | 3,086
primary Sjogren syndrome 1 | 789
primary pancreatic ductal adenocarcinoma 1 | 1,271
subependymal giant cell astrocytoma 1 | 2,287
ulcerative colitis 1 | 2,087

Tissue

Blood and immune system 14 | 17,995
Cardiovascular System 14 | 17,958
Digestive Tract 14 | 18,473
Endocrine System 14 | 18,512
Female tissues 14 | 18,647
Liver and Pancreas 14 | 18,136
Male tissues 14 | 17,969
Nervous System 14 | 18,561
Respiratory system 14 | 17,484
Skin and soft tissues 14 | 18,115
Urinary Tract 14 | 18,444

Target Family

Enzyme 7 | 4,146
Non-IDG 5 | 11,971
Epigenetic 1 | 242
Kinase 1 | 634

GWAS Trait

Plasma omega-6 polyunsaturated... 14 | 14
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1/FVC r... 192 | 192
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 112 | 112
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1/FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pyridoxal-dependent decarboxylase domain-containing protein 1 PDXDC1 Tbio Enzyme 1.09 112
Microtubule-associated serine/threonine-protein kinase 4 MAST4 Tbio Kinase -1.05387 12.9 73
Kelch repeat and BTB domain-containing protein 12 KBTBD12 Tdark Non-IDG 1.00 0.08 20
Calcium-dependent phospholipase A2 PLA2G5 Tchem Enzyme -1.40653 26.7 110
Endophilin-A3 SH3GL3 Tbio Non-IDG -1.01922 9.86 73
Leucine-rich repeat transmembrane neuronal protein 4 LRRTM4 Tdark Non-IDG -0.66354 4.56 54
Sn1-specific diacylglycerol lipase alpha DAGLA Tchem Enzyme -1.02825 11.2 118
Fatty acid desaturase 2 FADS2 Tchem Enzyme -2.49457 326.0 113
Glucoside xylosyltransferase 1 GXYLT1 Tdark Enzyme 0.12 0.49 49
Interleukin-23 receptor IL23R Tbio Non-IDG -2.06302 104.8 305