Development Level

Tbio 3 | 11,445

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

decreased fasted circulating g... 1 | 65
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96

Disease

Carcinoma 3 | 11,493
glioblastoma 3 | 5,792
Astrocytoma, Pilocytic 2 | 3,081
Breast cancer 2 | 3,578
Pick disease 2 | 1,894
atypical teratoid / rhabdoid tumor 2 | 5,112
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
interstitial cystitis 2 | 2,312
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
ovarian cancer 2 | 8,520
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Adenocarcinoma Of Esophagus 1 | 14
Autophagic vaculoes (finding) 1 | 3
Barth syndrome 1 | 23
Blushing 1 | 4
CARDIOMYOPATHY, DILATED, 1C (disorder) 1 | 1
Cardiomyopathies 1 | 110
Cardiomyopathy 1 | 116
Cardiomyopathy, Dilated 1 | 83
Cardiomyopathy, Dilated, 1C, With or Without Left Ventricular Noncompaction 1 | 1
Celiac disease 1 | 116
Coronary aneurysm 1 | 4
Coronary artery disease 1 | 268
Creatine phosphokinase serum increased 1 | 110
Diabetic Nephropathies 1 | 37
Diabetic Nephropathy 1 | 34
Dilated cardiomyopathy 1 | 56
Disseminated intravascular coagulation 1 | 38
EMG: myopathic abnormalities 1 | 22
EMG: neuropathic changes 1 | 15
Elevated creatine kinase 1 | 110
Facial erythema 1 | 4
Familial dermographism 1 | 1
Familial hemophagocytic lymphohistiocytosis 1 1 | 11
Familial hemophagocytic lymphohistiocytosis 2 1 | 15
Familial isolated dilated cardiomyopathy 1 | 41
Heart conduction disease 1 | 83
Hyporeflexia of lower limbs 1 | 10
Kidney cancer 1 | 2,613
Kidney disease 1 | 430
LEFT VENTRICULAR NONCOMPACTION 10 1 | 40
LEFT VENTRICULAR NONCOMPACTION 8 1 | 40
Left ventricular noncompaction 1 | 26
Leukemia 1 | 104
Muscle fiber splitting 1 | 7
Muscle weakness, distal, progressive 1 | 2
Muscle weakness, progressive, proximal 1 | 1
Myofibrillar Myopathy 1 | 9
Myofibrillar myopathy 4 1 | 4
Myopathy 1 | 185
Myopathy, Myofibrillar, Zasp-Related 1 | 1
Peripheral Neuropathy 1 | 134
Polyneuropathy 1 | 64
Primary biliary cirrhosis 1 | 51
Rosacea 1 | 25
Ruddy face 1 | 4
Stevens-Johnson syndrome 1 | 92
Urticaria 1 | 67
Vertebrobasilar insufficiency 1 | 9
Vibratory urticaria 1 | 1
acute quadriplegic myopathy 1 | 1,158
adult high grade glioma 1 | 3,801
astrocytoma 1 | 1,146
colon cancer 1 | 1,478
group 3 medulloblastoma 1 | 4,104
group 4 medulloblastoma 1 | 1,855
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung adenocarcinoma 1 | 2,716
malignant mesothelioma 1 | 3,232
medulloblastoma, large-cell 1 | 6,241
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Non-IDG 2 | 12,091
GPCR 1 | 408

GWAS Trait

Plasma androstenedione levels ... 3 | 3
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adhesion G protein-coupled receptor E2 ADGRE2 Tbio GPCR -1.67862 48.2 312
Engulfment and cell motility protein 1 ELMO1 Tbio Non-IDG -1.62242 45.4 178
LIM domain-binding protein 3 LDB3 Tbio Non-IDG -2.87973 736.4 182