Development Level

Tbio 8 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal coat-hair pigmentatio... 1 | 64
abnormal lens morphology 1 | 81
cataract 1 | 92
decreased circulating alanine ... 1 | 47
increased circulating total pr... 1 | 28
increased mean platelet volume 1 | 45
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 8 | 11,493
atypical teratoid / rhabdoid tumor 6 | 5,112
lung adenocarcinoma 6 | 2,716
non-small cell lung cancer 6 | 2,890
Breast cancer 5 | 3,578
Kidney cancer 5 | 2,613
glioblastoma 5 | 5,792
lung cancer 5 | 4,740
lung carcinoma 5 | 2,843
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
ependymoma 4 | 4,679
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
ulcerative colitis 4 | 1,819
Autosomal recessive predisposition 3 | 1,442
Colorectal Neoplasms 3 | 243
Liver Cirrhosis, Experimental 3 | 769
Melanoma 3 | 711
Skin cancer 3 | 469
adrenocortical carcinoma 3 | 1,428
fibroadenoma 3 | 559
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Atopic dermatitis 2 | 952
Attention Deficit Disorder with Hyperactivity 2 | 21
Attention deficit hyperactivity disorder 2 | 278
Barrett's esophagus 2 | 182
Breast Neoplasms 2 | 445
Cancer 2 | 2,499
Chronic obstructive pulmonary disease 2 | 184
DIARRHEA 6 2 | 2
Down syndrome 2 | 499
Mammary Neoplasms 2 | 425
Meconium ileus 2 | 3
Osteoporosis 2 | 363
Type 2 diabetes mellitus 2 | 272
acute myeloid leukemia 2 | 783
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
sonic hedgehog group medulloblastoma 2 | 467
Achromasia 1 | 11
Albinism 1 | 11
Alcohol dependence 1 | 107
Alcoholic Intoxication, Chronic 1 | 289
Autistic Disorder 1 | 364
Chromosome 9p deletion syndrome 1 | 13
Coarse facial features 1 | 108
Coffin-Siris syndrome 1 | 17
Constipation 1 | 181
Creutzfeldt-Jakob Syndrome 1 | 10
Creutzfeldt-Jakob disease 1 | 21
Decreased platelet count 1 | 111
Dental caries 1 | 164
Diarrhea 1 | 253
Ectodermal Dysplasia 1 | 14
Globe disease 1 | 67
Hermansky-Pudlak syndrome 1 | 42
Hip Dislocation, Congenital 1 | 48
Irritable bowel syndrome 1 | 60
Low Vision 1 | 174
Motor delay 1 | 147
Neural Tube Defects 1 | 31
Neutropenia 1 | 72
Neutrophil count decreased 1 | 47
No development of motor milestones 1 | 147
Oculocutaneous albinism 1 | 29
Panic disorder 1 | 61
Patent foramen ovale 1 | 10
Photodysphoria 1 | 121
Photophobia 1 | 121
Platelet storage pool deficiency 1 | 21
Prenatal onset 1 | 139
Recurrent bacterial infection 1 | 42
Skin Ulcer 1 | 48
Stereotypic Movement Disorder 1 | 42
Thickened facial skin with coarse facial features 1 | 108
Thin upper lip vermilion 1 | 67
Thrombocytopenia 1 | 197
Visual Impairment 1 | 174
Vitiligo 1 | 73
facioscapulohumeral dystrophy 1 | 288
non-small cell lung carcinoma 1 | 317
posterior fossa group A ependymoma 1 | 468

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 11 | 15,192

Target Family

Non-IDG 7 | 12,091
Enzyme 4 | 4,145
GPCR 1 | 408
Kinase 1 | 634

GWAS Trait

Pediatric bone mineral content... 13 | 13
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Heat-stable enterotoxin receptor GUCY2C Tclin Kinase -2.33494 214.5 228
Cadherin-like and PC-esterase domain-containing protein 1 CPED1 Tdark Enzyme -0.71710 4.99 26
Rab effector Noc2 RPH3AL Tbio Non-IDG -1.26757 23.0 148
Estradiol 17-beta-dehydrogenase 11 HSD17B11 Tbio Enzyme -0.99026 11.0 141
AP-3 complex subunit beta-1 AP3B1 Tbio Non-IDG -1.27699 21.0 89
Cytokine-dependent hematopoietic cell linker CLNK Tbio Non-IDG -2.66433 449.7 64
Uncharacterized protein C12orf60 C12orf60 Tdark Non-IDG 1.34 0.04 20
Anterior gradient protein 3 AGR3 Tbio Non-IDG -1.30719 19.5 219
Ribosome biogenesis protein BMS1 homolog BMS1 Tbio Non-IDG -1.44213 28.2 53