Development Level

Tbio 4 | 11,445

IMPC Phenotype

decreased body weight 1 | 161
increased startle reflex 1 | 112

Disease

Breast cancer 3 | 3,578
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
medulloblastoma, large-cell 3 | 6,241
ovarian cancer 3 | 8,520
Carcinoma 2 | 11,493
Pick disease 2 | 1,894
acute myeloid leukemia 2 | 783
colon cancer 2 | 1,478
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
osteosarcoma 2 | 7,950
pediatric high grade glioma 2 | 1,064
psoriasis 2 | 6,694
tuberculosis 2 | 2,010
Accelerated bone age after puberty 1 | 2
Acquired flat foot 1 | 72
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Animal Mammary Neoplasms 1 | 136
Annular pancreas 1 | 12
Arthralgia 1 | 90
Atypical chronic myeloid leukemia 1 | 4
Bone Diseases, Developmental 1 | 27
Bone pain 1 | 42
Brachydactyly 1 | 156
Bushy eyebrows 1 | 49
Cardiomyopathy, Hypertrophic, Familial 1 | 9
Cone-shaped epiphyses 1 | 24
Cone-shaped epiphyses of middle phalanges 1 | 2
Cone-shaped epiphyses of phalanges 1 | 15
Congenital neurologic anomalies 1 | 20
Congenital pectus carinatum 1 | 52
Cornelia de Lange syndrome 1 | 21
Coxa Magna 1 | 1
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Deep philtrum 1 | 21
Dental caries 1 | 164
Depressed philtrum 1 | 21
Ebstein anomaly 1 | 16
Esophageal Neoplasms 1 | 69
Esophageal Squamous Cell Carcinoma 1 | 77
Familial isolated dilated cardiomyopathy 1 | 41
Fine hair 1 | 42
Flat proximal femoral epiphyses 1 | 8
Flatfoot 1 | 73
Fragile nails 1 | 16
Generalized osteopenia 1 | 99
Hemolytic anemia 1 | 77
Hypertrichosis 1 | 46
Hypoplastic feet 1 | 66
Hypoplastic finger 1 | 17
Inadequate arch length for tooth size 1 | 45
Infantile muscular hypotonia 1 | 12
Keloid 1 | 37
Koilonychia 1 | 7
LEFT VENTRICULAR NONCOMPACTION 10 1 | 40
LEFT VENTRICULAR NONCOMPACTION 8 1 | 40
Langer-Giedion Syndrome 1 | 2
Late tooth eruption 1 | 61
Laterally sparse eyebrows 1 | 12
Left ventricular noncompaction 1 | 26
Legg-Calve-Perthes disease 1 | 14
Leukonychia 1 | 6
Lordosis 1 | 54
Malocclusion 1 | 57
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Microdontia (disorder) 1 | 59
Multiple exostoses of long tubular bones 1 | 2
Narrow palate 1 | 20
Osteopenia 1 | 99
Pear-shaped nose 1 | 2
Rotting teeth 1 | 73
Scapular weakness 1 | 23
Short distal phalanges 1 | 50
Short finger 1 | 17
Short hands 1 | 50
Short metatarsal 1 | 21
Short phalanx of finger 1 | 32
Slow-growing hair 1 | 19
Sparse eyebrow 1 | 42
Sparse eyelashes 1 | 31
Sparse scalp hair 1 | 42
Squamous cell carcinoma of esophagus 1 | 77
Tachycardia, Ventricular 1 | 22
Thin hypoplastic alae nasi 1 | 51
Thin nails 1 | 5
Thin upper lip vermilion 1 | 67
Tooth Crowding 1 | 45
Tooth mass arch size discrepancy 1 | 45
Tooth size discrepancy 1 | 45
Tooth, Supernumerary 1 | 7
Trichorhinophalangeal Syndrome, Type III 1 | 1
Trichorhinophalangeal dysplasia type I 1 | 1
Trichorhinophalangeal syndrome type I 1 | 8
Winged scapula 1 | 23

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 3 | 12,091
Transcription Factor 1 | 1,400

GWAS Trait

Parkinson's disease (familial,... 4 | 4
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tropomyosin alpha-1 chain TPM1 Tbio Non-IDG -2.19537 154.3 227
Kelch domain-containing protein 1 KLHDC1 Tbio Non-IDG 0.38 0.47 78
Zinc finger transcription factor Trps1 TRPS1 Tbio Transcription Factor -1.98756 107.0 69
LHFPL tetraspan subfamily member 2 protein LHFPL2 Tbio Non-IDG -0.30566 1.99 45