Development Level

Tbio 12 | 10,625
Tdark 6 | 7,003
Tchem 2 | 1,890
Tclin 1 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

decreased grip strength 2 | 123
abnormal bone mineralization 1 | 55
abnormal heart morphology 1 | 51
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased mature B cell number 1 | 25
enlarged heart 1 | 111
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119

Disease

atypical teratoid / rhabdoid tumor 9 | 4,369
glioblastoma 9 | 5,572
osteosarcoma 9 | 7,933
ovarian cancer 9 | 8,484
psoriasis 9 | 6,685
malignant mesothelioma 8 | 3,162
pilocytic astrocytoma 7 | 3,086
ependymoma 5 | 2,514
interstitial cystitis 5 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
lung cancer 5 | 4,466
medulloblastoma, large-cell 5 | 6,234
pediatric high grade glioma 5 | 2,712
Breast cancer 4 | 3,094
Carcinoma 4 | 2,147
Rheumatoid Arthritis 4 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
invasive ductal carcinoma 4 | 2,950
oligodendroglioma 4 | 2,849
primitive neuroectodermal tumor 4 | 3,031
Alzheimer's disease 3 | 644
active ulcerative colitis 3 | 477
dermatomyositis 3 | 933
group 4 medulloblastoma 3 | 1,875
lung adenocarcinoma 3 | 2,713
lung carcinoma 3 | 2,844
non primary Sjogren syndrome sicca 3 | 840
pancreatic cancer 3 | 2,300
pituitary cancer 3 | 1,972
posterior fossa group B ependymoma 3 | 1,530
primary pancreatic ductal adenocarcinoma 3 | 1,271
sonic hedgehog group medulloblastoma 3 | 1,482
Acquired metabolic disease 2 | 267
Cancer 2 | 2,346
Chronic Obstructive Airway Disease 2 | 47
Kidney cancer 2 | 118
Parkinson's disease 2 | 364
Schizophrenia 2 | 501
adrenocortical carcinoma 2 | 1,427
adult high grade glioma 2 | 2,148
astrocytic glioma 2 | 2,241
atypical teratoid/rhabdoid tumor 2 | 1,095
breast carcinoma 2 | 1,614
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,475
cutaneous lupus erythematosus 2 | 1,056
ductal carcinoma in situ 2 | 1,745
medulloblastoma 2 | 1,524
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056
spina bifida 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,557
tuberculosis and treatment for 6 months 2 | 686
ulcerative colitis 2 | 2,087
urothelial carcinoma 2 | 318
Adenoid Cystic Carcinoma 1 | 99
Amphetamine-Related Disorders 1 | 74
Amyotrophic Lateral Sclerosis 1 | 431
Atopic dermatitis 1 | 944
Blood pressure finding 1 | 56
Cadmium poisoning 1 | 3
Cannabis dependence 1 | 18
Choreatic disease 1 | 27
Colorectal Neoplasms 1 | 217
Coronary Restenosis 1 | 8
Dementia 1 | 129
Hearing Loss, Partial 1 | 25
Hepatic vein thrombosis 1 | 8
Holoprosencephaly 1 | 52
Huntington Disease 1 | 12
Huntington's disease 1 | 72
Hypersensitivity reaction type II disease 1 | 235
Hypertension 1 | 287
IGA Glomerulonephritis 1 | 454
Immune system cancer 1 | 38
Inflammatory Bowel Diseases 1 | 87
Inflammatory dermatosis 1 | 38
Juvenile Huntington Disease 1 | 1
Kennedy's disease 1 | 13
Liver cancer 1 | 31
Machado-Joseph disease 1 | 18
Manganese Poisoning 1 | 11
Movement Disorders 1 | 21
Neurodegenerative disease 1 | 383
Polycystic Ovary Syndrome 1 | 332
Spontaneous abortion 1 | 108
Substance-Related Disorders 1 | 114
Systemic arterial pressure 1 | 56
Toxic encephalopathy 1 | 131
active Crohn's disease 1 | 918
cystic fibrosis 1 | 1,665
dentatorubral-pallidoluysian atrophy 1 | 21
glioblastoma multiforme 1 | 347
hearing impairment 1 | 40
hereditary spastic paraplegia 1 | 313
progressive supranuclear palsy 1 | 674
severe Alzheimer's disease 1 | 49
tuberculosis and treatment for 3 months 1 | 327

Tissue

Cardiovascular System 21 | 17,958
Digestive Tract 21 | 18,473
Endocrine System 21 | 18,512
Female tissues 21 | 18,647
Liver and Pancreas 21 | 18,136
Nervous System 21 | 18,561
Respiratory system 21 | 17,484
Urinary Tract 21 | 18,444
Blood and immune system 20 | 17,995
Male tissues 20 | 17,969
Skin and soft tissues 20 | 18,115

Target Family

Non-IDG 17 | 11,971
Enzyme 3 | 4,146
Kinase 1 | 634

GWAS Trait

Parental longevity (mother's a... 21 | 21
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1/FVC r... 192 | 192
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 112 | 112
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1/FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

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