Development Level

Tbio 27 | 11,445
Tdark 7 | 6,588
Tclin 5 | 613
Tchem 2 | 1,598

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 4 | 979
persistence of hyaloid vascula... 2 | 33
prenatal lethality prior to he... 2 | 87
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal motor capabilities-co... 1 | 5
abnormal tooth morphology 1 | 24
abnormal urination 1 | 1
absent startle reflex 1 | 24
cataract 1 | 92
decreased anxiety-related resp... 1 | 12
decreased bone mineral content 1 | 151
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body weight 1 | 25
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased fluid intake 1 | 1
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 29 | 11,493
medulloblastoma, large-cell 24 | 6,241
glioblastoma 22 | 5,792
psoriasis 22 | 6,694
atypical teratoid / rhabdoid tumor 19 | 5,112
ovarian cancer 19 | 8,520
ependymoma 18 | 4,679
lung cancer 18 | 4,740
Kidney cancer 16 | 2,613
group 3 medulloblastoma 15 | 4,104
osteosarcoma 15 | 7,950
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
oligodendroglioma 14 | 2,850
adult high grade glioma 13 | 3,801
primitive neuroectodermal tumor 13 | 3,035
Breast cancer 12 | 3,578
Pick disease 12 | 1,894
astrocytic glioma 12 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
Astrocytoma, Pilocytic 11 | 3,081
Schizophrenia 11 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
lung carcinoma 11 | 2,843
malignant mesothelioma 11 | 3,232
invasive ductal carcinoma 10 | 2,951
Cancer 9 | 2,499
Melanoma 9 | 711
lung adenocarcinoma 9 | 2,716
non-small cell lung cancer 9 | 2,890
pituitary cancer 9 | 1,972
Skin cancer 8 | 469
breast carcinoma 8 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Obesity 7 | 678
diabetes mellitus 7 | 1,728
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
juvenile dermatomyositis 7 | 1,187
pancreatic cancer 7 | 2,398
subependymal giant cell astrocytoma 7 | 2,287
Attention deficit hyperactivity disorder 6 | 278
Autosomal recessive predisposition 6 | 1,442
Liver cancer 6 | 604
Parkinson's disease 6 | 392
acute quadriplegic myopathy 6 | 1,158
ductal carcinoma in situ 6 | 1,745
pediatric high grade glioma 6 | 1,064
posterior fossa group B ependymoma 6 | 416
ulcerative colitis 6 | 1,819
Amyotrophic lateral sclerosis 5 | 451
Atopic dermatitis 5 | 952
Bipolar Disorder 5 | 666
Depressive disorder 5 | 409
Heart disease 5 | 306
Major Depressive Disorder 5 | 301
tuberculosis 5 | 2,010
Atherosclerosis 4 | 291
Kidney disease 4 | 430
Mental Depression 4 | 333
Neurogenic Muscular Atrophy 4 | 139
Neurogenic muscle atrophy, especially in the lower limbs 4 | 139
Rheumatoid arthritis 4 | 1,191
Skeletal muscle atrophy 4 | 139
Unipolar Depression 4 | 250
acute myeloid leukemia 4 | 783
colon cancer 4 | 1,478
cutaneous lupus erythematosus 4 | 1,057
gastric carcinoma 4 | 807
muscle degeneration 4 | 139
nephrosclerosis 4 | 333
non primary Sjogren syndrome sicca 4 | 891
Alcoholic Intoxication, Chronic 3 | 289
Alzheimer's disease 3 | 658
Anxiety 3 | 136
Anxiety disease 3 | 113
Cardiovascular system disease 3 | 246
Cerebrovascular disease 3 | 238
Chemical and Drug Induced Liver Injury 3 | 195
Cognitive delay 3 | 608
Coronary artery disease 3 | 268
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Endometrial cancer 3 | 311
Fatigue 3 | 182
Global developmental delay 3 | 608
Huntington's disease 3 | 76
Hypertension 3 | 396
Intellectual disability 3 | 1,016
Lipid metabolism disorder 3 | 114
Mental and motor retardation 3 | 608
Mood swings 3 | 77
Nerve Degeneration 3 | 121
Neurodegenerative disease 3 | 414
Toxic encephalopathy 3 | 141
adrenocortical carcinoma 3 | 1,428
dermatomyositis 3 | 966
fibroadenoma 3 | 559
tuberculosis and treatment for 6 months 3 | 409
cystic fibrosis 2 | 1,696
nasopharyngeal carcinoma 2 | 1,058

Tissue

Endocrine System 40 | 18,159
Skin and soft tissues 40 | 17,230
Digestive Tract 39 | 17,369
Female tissues 39 | 17,400
Male tissues 39 | 17,142
Nervous System 39 | 16,725
Respiratory system 37 | 16,393
Urinary Tract 37 | 16,678
Blood and immune system 36 | 16,909
Liver and Pancreas 36 | 16,750
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 25 | 12,091
Enzyme 7 | 4,145
Transcription Factor 3 | 1,400
Ion Channel 2 | 344
GPCR 1 | 408
Kinase 1 | 634
TF/Epigenetic 1 | 38
Transporter 1 | 473

GWAS Trait

Parental longevity (combined p... 41 | 41
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myelin transcription factor 1-like protein MYT1L Tbio Transcription Factor -1.49407 30.1 40
Vacuolar protein sorting-associated protein 13A VPS13A Tbio Non-IDG -2.19966 172.3 22
G patch domain-containing protein 1 GPATCH1 Tdark Non-IDG 0.54 0.26 14
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Cell migration-inducing and hyaluronan-binding protein CEMIP Tbio Non-IDG -1.58210 41.5 144
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236
Ankyrin repeat domain-containing protein 27 ANKRD27 Tbio Non-IDG -1.12548 14.6 65
DNA topoisomerase 3-alpha TOP3A Tbio Enzyme -2.77897 560.7 45
Iron-responsive element-binding protein 2 IREB2 Tbio Non-IDG -2.33609 211.7 253
Plexin-B2 PLXNB2 Tbio Non-IDG -1.25236 17.4 82