Development Level

Tbio 27 | 11,445
Tdark 18 | 6,588
Tchem 6 | 1,598
Tclin 5 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal mouth morphology 1 | 1
abnormal retinal inner nuclear... 1 | 8
abnormal skin morphology 1 | 50
abnormal stomach morphology 1 | 10
anophthalmia 1 | 33
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased eosinophil cell numb... 1 | 24
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
dilated heart left ventricle 1 | 11
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
increased cardiac stroke volum... 1 | 1
increased circulating iron lev... 1 | 30
increased erythrocyte cell num... 1 | 39
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
thick ventricular wall 1 | 7

Disease

Carcinoma 36 | 11,493
osteosarcoma 27 | 7,950
ovarian cancer 27 | 8,520
psoriasis 26 | 6,694
glioblastoma 25 | 5,792
medulloblastoma, large-cell 22 | 6,241
adult high grade glioma 21 | 3,801
atypical teratoid / rhabdoid tumor 21 | 5,112
group 3 medulloblastoma 20 | 4,104
ependymoma 19 | 4,679
Breast cancer 18 | 3,578
primitive neuroectodermal tumor 18 | 3,035
Astrocytoma, Pilocytic 16 | 3,081
lung cancer 16 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
lung adenocarcinoma 15 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
malignant mesothelioma 14 | 3,232
non-small cell lung cancer 14 | 2,890
oligodendroglioma 14 | 2,850
pituitary cancer 13 | 1,972
lung carcinoma 12 | 2,843
invasive ductal carcinoma 11 | 2,951
astrocytic glioma 10 | 2,597
subependymal giant cell astrocytoma 10 | 2,287
Cancer 9 | 2,499
interstitial cystitis 9 | 2,312
Kidney cancer 8 | 2,613
colon cancer 8 | 1,478
Endometriosis 7 | 540
Rheumatoid arthritis 7 | 1,191
Schizophrenia 7 | 1,160
ductal carcinoma in situ 7 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Atopic dermatitis 6 | 952
Pick disease 6 | 1,894
cutaneous lupus erythematosus 6 | 1,057
pancreatic cancer 6 | 2,398
tuberculosis 6 | 2,010
Bipolar Disorder 5 | 666
Epilepsy 5 | 792
breast carcinoma 5 | 1,638
esophageal adenocarcinoma 5 | 737
Alzheimer's disease 4 | 658
Autosomal recessive predisposition 4 | 1,442
Liver Cirrhosis, Experimental 4 | 769
Mental Depression 4 | 333
Parkinson's disease 4 | 392
active ulcerative colitis 4 | 764
aldosterone-producing adenoma 4 | 665
cystic fibrosis 4 | 1,696
fibroadenoma 4 | 559
group 4 medulloblastoma 4 | 1,855
medulloblastoma 4 | 720
non primary Sjogren syndrome sicca 4 | 891
primary pancreatic ductal adenocarcinoma 4 | 1,109
ulcerative colitis 4 | 1,819
Amyotrophic lateral sclerosis 3 | 451
Autistic Disorder 3 | 364
Cognitive delay 3 | 608
Depressive disorder 3 | 409
Dull intelligence 3 | 645
Global developmental delay 3 | 608
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Poor school performance 3 | 645
Prostatic Neoplasms 3 | 495
Seizures 3 | 596
adrenocortical carcinoma 3 | 1,428
atypical teratoid/rhabdoid tumor 3 | 357
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
head and neck cancer 3 | 271
posterior fossa group A ependymoma 3 | 468
spina bifida 3 | 1,074
Down syndrome 2 | 499
Highly variable severity 2 | 157
Liver cancer 2 | 604
Neurodegenerative disease 2 | 414
Neuropathy 2 | 261
Polycystic ovary syndrome 2 | 360
Small head 2 | 374
Strabismus 2 | 270
Toxic encephalopathy 2 | 141
Type 2 diabetes mellitus 2 | 272
Variable expressivity 2 | 157
Vascular disease 2 | 319
acute quadriplegic myopathy 2 | 1,158
adrenocortical adenoma 2 | 131
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic rhinosinusitis 2 | 512
hereditary spastic paraplegia 2 | 318
juvenile dermatomyositis 2 | 1,187
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676

Tissue

Blood and immune system 53 | 16,909
Digestive Tract 53 | 17,369
Skin and soft tissues 53 | 17,230
Endocrine System 52 | 18,159
Female tissues 52 | 17,400
Liver and Pancreas 52 | 16,750
Male tissues 52 | 17,142
Nervous System 52 | 16,725
Urinary Tract 52 | 16,678
Respiratory system 51 | 16,393
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 33 | 12,091
Enzyme 10 | 4,145
Ion Channel 4 | 344
Transporter 4 | 473
Transcription Factor 2 | 1,400
GPCR 1 | 408
Kinase 1 | 634
Nuclear Receptor 1 | 48

GWAS Trait

Parental extreme longevity (95... 56 | 56
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 Tbio Enzyme -1.43954 27.0 162
TBC1 domain family member 13 TBC1D13 Tdark Non-IDG -0.10266 1.34 92
A disintegrin and metalloproteinase with thrombospondin motifs 1 ADAMTS1 Tchem Enzyme -2.44459 279.8 227
Roundabout homolog 2 ROBO2 Tbio Non-IDG -1.89275 74.1 161
Protein unc-93 homolog A UNC93A Tdark Non-IDG -0.28738 2.63 81
Putative protein C3P1 C3P1 Tdark Non-IDG 0.00000 0
AP-5 complex subunit zeta-1 AP5Z1 Tbio Transcription Factor -0.53740 2.90 61
Testican-1 SPOCK1 Tbio Non-IDG -1.99465 104.6 92
Protein FAM107B FAM107B Tdark Non-IDG -0.22185 2.53 28
Replication protein A 14 kDa subunit RPA3 Tbio Non-IDG -1.85941 67.1 171