Development Level

Tbio 24 | 11,651
Tchem 3 | 1,388
Tdark 3 | 6,593

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal sleep behavior 1 | 70
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 25 | 11,493
ovarian cancer 18 | 8,520
pancreatic cancer 18 | 2,398
osteosarcoma 16 | 7,950
ependymoma 13 | 4,679
lung cancer 13 | 4,740
atypical teratoid / rhabdoid tumor 12 | 5,112
glioblastoma 12 | 5,792
medulloblastoma, large-cell 12 | 6,241
Breast cancer 10 | 3,578
Cancer 10 | 2,499
group 3 medulloblastoma 10 | 4,104
Kidney cancer 9 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
lung carcinoma 9 | 2,843
Pancreatic Neoplasm 8 | 85
Pancreatic Neoplasms 8 | 85
adult high grade glioma 8 | 3,801
non-small cell lung cancer 8 | 2,890
psoriasis 8 | 6,694
invasive ductal carcinoma 7 | 2,951
primitive neuroectodermal tumor 7 | 3,035
Astrocytoma, Pilocytic 6 | 3,081
Pick disease 6 | 1,894
Acquired metabolic disease 5 | 336
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
diabetes mellitus 5 | 1,728
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
juvenile dermatomyositis 5 | 1,187
subependymal giant cell astrocytoma 5 | 2,287
Amyotrophic lateral sclerosis 4 | 451
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
dermatomyositis 4 | 966
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
primary pancreatic ductal adenocarcinoma 4 | 1,109
Adenocarcinoma 3 | 122
Alzheimer's disease 3 | 658
Bipolar Disorder 3 | 666
Cardiovascular system disease 3 | 246
Colorectal Neoplasms 3 | 243
Dental caries 3 | 164
Dull intelligence 3 | 645
Epilepsy 3 | 792
Intellectual disability 3 | 1,016
Liver cancer 3 | 604
Low intelligence 3 | 645
Lung Neoplasms 3 | 232
Lymphoid leukemia 3 | 160
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
Short stature 3 | 531
active ulcerative colitis 3 | 764
aldosterone-producing adenoma 3 | 665
astrocytic glioma 3 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
non primary Sjogren syndrome sicca 3 | 891
oligodendroglioma 3 | 2,850
pediatric high grade glioma 3 | 1,064
Adenocarcinoma of lung 2 | 142
Adenoma 2 | 167
Bladder Neoplasm 2 | 112
Blepharoptosis 2 | 231
Depressive disorder 2 | 409
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Endometriosis 2 | 540
Essential Hypertension 2 | 94
Failure to gain weight 2 | 365
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Kidney disease 2 | 430
Mental Depression 2 | 333
Neurodegenerative disease 2 | 414
Neuropathy 2 | 261
Osteoporosis 2 | 363
Pediatric failure to thrive 2 | 365
Phenotypic variability 2 | 150
Prostate cancer 2 | 175
Refractive error 2 | 50
Sparse hair 2 | 59
Thin, sparse hair 2 | 59
Urinary Bladder Neoplasms 2 | 114
fibroadenoma 2 | 559
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
posterior fossa group A ependymoma 2 | 468
tuberculosis and treatment for 3 months 2 | 179
tuberculosis and treatment for 6 months 2 | 409

Tissue

Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Liver and Pancreas 28 | 16,750
Skin and soft tissues 28 | 17,230
Female tissues 27 | 17,400
Male tissues 27 | 17,142
Urinary Tract 27 | 16,678
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Blood and immune system 25 | 16,909
Cardiovascular System 25 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 7 | 4,145
Transcription Factor 4 | 1,400
Ion Channel 1 | 344
Kinase 1 | 634
Nuclear Receptor 1 | 48
Transporter 1 | 473

GWAS Trait

Pancreatic cancer 30 | 30
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
General transcription factor IIH subunit 1 GTF2H1 Tbio Non-IDG -1.65323 46.0 231
Dipeptidyl aminopeptidase-like protein 6 DPP6 Tbio Enzyme -2.06587 114.8 131
Unconventional myosin-Id MYO1D Tbio Non-IDG -1.39704 23.1 63
Disabled homolog 2 DAB2 Tbio Non-IDG -2.26146 184.8 239
Glutamate receptor ionotropic, delta-1 GRID1 Tbio Ion Channel -1.07838 10.7 166
E3 ubiquitin-protein ligase ZNRF3 ZNRF3 Tbio Enzyme -1.17415 16.1 57
Low-density lipoprotein receptor class A domain-containing protein 4 LDLRAD4 Tbio Non-IDG -1.56623 26.5 53
Tumor protein 63 TP63 Tbio Transcription Factor -3.07398 1154.1 448
Protein FAM19A5 FAM19A5 Tdark Non-IDG -0.21741 1.95 9
Transforming acidic coiled-coil-containing protein 1 TACC1 Tbio Non-IDG -1.28283 18.8 169