Development Level

Tbio 20 | 10,625
Tdark 3 | 7,003
Tchem 2 | 1,890

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

decreased Ly6C low monocyte nu... 1 | 23
decreased NK T cell number 1 | 28
decreased circulating alanine ... 1 | 53
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased monocyte cell number 1 | 28
decreased startle reflex 1 | 48
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 68
increased or absent threshold ... 1 | 128
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 16 | 8,484
osteosarcoma 14 | 7,933
pancreatic cancer 14 | 2,300
Malignant neoplasm of pancreas 12 | 14
glioblastoma 11 | 5,572
medulloblastoma, large-cell 11 | 6,234
Carcinoma 9 | 2,147
atypical teratoid / rhabdoid tumor 9 | 4,369
lung cancer 9 | 4,466
Breast cancer 8 | 3,094
Cancer 8 | 2,346
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
lung carcinoma 7 | 2,844
non-small cell lung cancer 7 | 2,798
pediatric high grade glioma 7 | 2,712
psoriasis 7 | 6,685
Pancreatic Neoplasm 6 | 79
posterior fossa group A ependymoma 6 | 1,511
Pick disease 5 | 1,893
cystic fibrosis 5 | 1,665
interstitial cystitis 5 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
invasive ductal carcinoma 5 | 2,950
juvenile dermatomyositis 5 | 1,189
pilocytic astrocytoma 5 | 3,086
primitive neuroectodermal tumor 5 | 3,031
sonic hedgehog group medulloblastoma 5 | 1,482
subependymal giant cell astrocytoma 5 | 2,287
Lung Neoplasms 4 | 171
acute quadriplegic myopathy 4 | 1,157
adrenocortical carcinoma 4 | 1,427
colon cancer 4 | 1,475
diabetes mellitus 4 | 1,663
malignant mesothelioma 4 | 3,162
primary pancreatic ductal adenocarcinoma 4 | 1,271
Acquired metabolic disease 3 | 267
Adenocarcinoma 3 | 115
Adenocarcinoma of lung (disorder) 3 | 48
Alzheimer's disease 3 | 644
Amyotrophic Lateral Sclerosis 3 | 431
Cardiovascular system disease 3 | 194
Colorectal Neoplasms 3 | 217
Lymphoid leukemia 3 | 69
Malignant neoplasm of lung 3 | 16
Neurodegenerative disease 3 | 383
Rheumatoid Arthritis 3 | 1,160
aldosterone-producing adenoma 3 | 664
dermatomyositis 3 | 933
ependymoma 3 | 2,514
gastric carcinoma 3 | 832
group 3 medulloblastoma 3 | 2,254
group 4 medulloblastoma 3 | 1,875
lung adenocarcinoma 3 | 2,713
ovarian neoplasm 3 | 97
posterior fossa group B ependymoma 3 | 1,530
ulcerative colitis 3 | 2,087
Adenoma 2 | 165
Autistic Disorder 2 | 320
Basal cell carcinoma 2 | 29
Bladder Neoplasm 2 | 109
Cleft Lip 2 | 91
Down syndrome 2 | 548
Gout 2 | 93
Leprosy 2 | 77
Melanoma 2 | 261
Prostate cancer 2 | 172
Prostatic Neoplasms 2 | 471
Tooth agenesis 2 | 36
Uterine Cervical Neoplasm 2 | 21
active ulcerative colitis 2 | 477
adult high grade glioma 2 | 2,148
astrocytoma 2 | 1,493
breast carcinoma 2 | 1,614
chronic lymphosyte leukemia 2 | 232
cutaneous lupus erythematosus 2 | 1,056
esophageal adenocarcinoma 2 | 737
facioscapulohumeral dystrophy 2 | 286
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056
non primary Sjogren syndrome sicca 2 | 840
non-small cell lung carcinoma 2 | 413
oligodendroglioma 2 | 2,849
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 674
sarcoidosis 2 | 358
tuberculosis and treatment for 6 months 2 | 686
Anovulation 1 | 20
Candidiasis 1 | 48
Child Development Disorders, Pervasive 1 | 55
Dyskeratosis congenita 1 | 24
Malignant glioma 1 | 23
Multiple system atrophy 1 | 27
Oropharynx cancer 1 | 7
PARKINSON DISEASE, LATE-ONSET 1 | 18
Pulmonary emphysema 1 | 34
Rift Valley fever 1 | 13
Silver-Russell syndrome 1 | 37
Syndactyly 1 | 56
Thyroid Neoplasm 1 | 33

Tissue

Blood and immune system 25 | 17,995
Cardiovascular System 25 | 17,958
Digestive Tract 25 | 18,473
Endocrine System 25 | 18,512
Female tissues 25 | 18,647
Liver and Pancreas 25 | 18,136
Male tissues 25 | 17,969
Nervous System 25 | 18,561
Respiratory system 25 | 17,484
Skin and soft tissues 25 | 18,115
Urinary Tract 25 | 18,444

Target Family

Non-IDG 12 | 11,971
Enzyme 7 | 4,146
Transcription Factor 3 | 1,400
Ion Channel 1 | 341
Kinase 1 | 634
Nuclear Receptor 1 | 48

GWAS Trait

Pancreatic cancer 25 | 25
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1/FVC r... 192 | 192
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 112 | 112
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1/FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutamate receptor ionotropic, delta-1 GRID1 Tbio Ion Channel -1.01738 9.38 156
E3 ubiquitin-protein ligase RNF149 RNF149 Tdark Enzyme 0.19 0.53 99
Low-density lipoprotein receptor class A domain-containing protein 4 LDLRAD4 Tbio Non-IDG -1.51136 24.6 45
Myotubularin-related protein 13 SBF2 Tbio Non-IDG -1.38149 25.3 8
Disabled homolog 2 DAB2 Tbio Non-IDG -2.22627 174.6 226
Dipeptidyl aminopeptidase-like protein 6 DPP6 Tbio Enzyme -2.01552 108.0 115
E3 ubiquitin-protein ligase ZNRF3 ZNRF3 Tbio Enzyme -1.05016 14.6 38
Inactive tyrosine-protein kinase transmembrane receptor ROR1 ROR1 Tbio Kinase -1.20211 22.9 280
Unconventional myosin-Id MYO1D Tbio Non-IDG -1.33703 22.2 57
Protein Wnt-2b WNT2B Tbio Non-IDG -1.68954 53.4 146