Development Level

Tbio 50 | 11,178
Tdark 16 | 6,569
Tchem 8 | 1,885
Tclin 6 | 612

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
enlarged lymph nodes 2 | 37
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retinal vasculature m... 1 | 27
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased coping response 1 | 8
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
hydrometra 1 | 53
hyperactivity 1 | 148
impaired righting response 1 | 26
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
pale yolk sac 1 | 25
prenatal lethality 1 | 28
small superior vagus ganglion 1 | 74

Disease

Carcinoma 58 | 11,192
medulloblastoma, large-cell 42 | 6,086
psoriasis 42 | 6,514
glioblastoma 41 | 5,635
ovarian cancer 38 | 8,297
ependymoma 35 | 4,559
osteosarcoma 35 | 7,766
atypical teratoid / rhabdoid tumor 34 | 4,971
lung cancer 34 | 4,607
Breast cancer 29 | 3,469
oligodendroglioma 28 | 2,768
group 3 medulloblastoma 27 | 4,002
Kidney cancer 25 | 2,548
adult high grade glioma 24 | 3,701
primitive neuroectodermal tumor 22 | 2,957
Astrocytoma, Pilocytic 21 | 3,006
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,902
lung carcinoma 21 | 2,755
non-small cell lung cancer 21 | 2,799
invasive ductal carcinoma 20 | 2,867
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,204
interstitial cystitis 18 | 2,237
astrocytic glioma 17 | 2,530
lung adenocarcinoma 17 | 2,627
cystic fibrosis 16 | 1,629
malignant mesothelioma 15 | 3,135
pancreatic cancer 15 | 2,322
pituitary cancer 15 | 1,915
ductal carcinoma in situ 13 | 1,686
Cancer 12 | 2,388
Melanoma 12 | 689
subependymal giant cell astrocytoma 12 | 2,230
Liver cancer 11 | 589
Pick disease 10 | 1,856
Schizophrenia 10 | 1,136
Skin cancer 10 | 451
colon cancer 10 | 1,428
astrocytoma 9 | 1,113
breast carcinoma 9 | 1,589
tuberculosis 9 | 1,963
Autistic Disorder 8 | 358
adrenocortical carcinoma 8 | 1,385
diabetes mellitus 8 | 1,683
pediatric high grade glioma 8 | 1,035
Atopic dermatitis 7 | 915
Bipolar Disorder 7 | 646
esophageal adenocarcinoma 7 | 696
group 4 medulloblastoma 7 | 1,806
primary pancreatic ductal adenocarcinoma 7 | 1,071
ulcerative colitis 7 | 1,765
Liver Cirrhosis, Experimental 6 | 733
Mental Depression 6 | 325
Obesity 6 | 655
Rheumatoid arthritis 6 | 1,156
Vascular disease 6 | 294
active ulcerative colitis 6 | 736
nasopharyngeal carcinoma 6 | 1,024
non primary Sjogren syndrome sicca 6 | 861
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,911
Acquired metabolic disease 5 | 329
Alzheimer's disease 5 | 640
Attention deficit hyperactivity disorder 5 | 272
Autosomal recessive predisposition 5 | 1,407
Colorectal Neoplasms 5 | 235
Major Depressive Disorder 5 | 293
Type 2 diabetes mellitus 5 | 268
Unipolar Depression 5 | 244
progressive supranuclear palsy 5 | 656
spina bifida 5 | 1,053
Cerebrovascular disease 4 | 223
Depressive disorder 4 | 401
Duchenne muscular dystrophy 4 | 587
Endometrial cancer 4 | 301
Epilepsy 4 | 775
Heart disease 4 | 288
Hypertension 4 | 372
Intellectual disability 4 | 998
Multiple myeloma 4 | 1,296
acute quadriplegic myopathy 4 | 1,133
gastric carcinoma 4 | 781
medulloblastoma 4 | 702
nephrosclerosis 4 | 314
pancreatic carcinoma 4 | 555
primary Sjogren syndrome 4 | 710
Acquired scoliosis 3 | 274
Crohn's disease 3 | 311
Curvature of spine 3 | 275
Endometriosis 3 | 521
Ventricular Septal Defects 3 | 113
active Crohn's disease 3 | 882
acute myeloid leukemia 3 | 760
aldosterone-producing adenoma 3 | 646
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 492
dermatomyositis 3 | 941
fibroadenoma 3 | 538
head and neck cancer 3 | 263
juvenile dermatomyositis 3 | 1,147
mucosa-associated lymphoid tissue lymphoma 3 | 473
sonic hedgehog group medulloblastoma 3 | 459

Tissue

Endocrine System 78 | 18,159
Female tissues 77 | 17,400
Nervous System 77 | 16,725
Digestive Tract 76 | 17,369
Male tissues 75 | 17,142
Urinary Tract 75 | 16,678
Skin and soft tissues 74 | 17,230
Blood and immune system 72 | 16,909
Respiratory system 72 | 16,393
Liver and Pancreas 71 | 16,750
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 44 | 12,091
Enzyme 16 | 4,145
GPCR 5 | 408
Ion Channel 4 | 344
Transcription Factor 4 | 1,400
Kinase 3 | 634
Transporter 2 | 473
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GWAS Trait

PR interval in Tripanosoma cru... 80 | 80
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Granulocyte-macrophage colony-stimulating factor CSF2 Tchem Non-IDG -3.91682 8450.3 1272
Cannabinoid receptor 1 CNR1 Tclin GPCR -3.71368 5235.6 431
Sulfatase-modifying factor 2 SUMF2 Tbio Enzyme -3.31286 2003.5 64
Thrombomodulin THBD Tbio Non-IDG -3.31892 1993.7 492
Glutamate receptor 1 GRIA1 Tclin Ion Channel -3.17077 1441.5 761
Serpin B5 SERPINB5 Tbio Non-IDG -3.04576 1104.8 385
Serine/threonine-protein kinase STK11 STK11 Tchem Kinase -2.96288 998.3 959
Retinol-binding protein 1 RBP1 Tbio Non-IDG -2.65868 476.2 195
FAS-associated death domain protein FADD Tbio Non-IDG -2.70083 469.8 708
Collagen alpha-2(I) chain COL1A2 Tchem Non-IDG -2.64284 404.0 258