Development Level

Tbio 31 | 11,445
Tdark 6 | 6,588
Tchem 4 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased body length 2 | 101
decreased body weight 2 | 161
increased startle reflex 2 | 112
abnormal allantois morphology 1 | 8
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal heart looping 1 | 5
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal placenta size 1 | 20
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal tail movements 1 | 12
abnormal visceral yolk sac mor... 1 | 6
decreased bone mineral content 1 | 151
decreased grip strength 1 | 116
decreased neutrophil cell numb... 1 | 42
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
limb grasping 1 | 41
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 34 | 11,493
Orofacial cleft 29 | 54
glioblastoma 22 | 5,792
osteosarcoma 21 | 7,950
medulloblastoma, large-cell 20 | 6,241
ovarian cancer 19 | 8,520
atypical teratoid / rhabdoid tumor 18 | 5,112
group 3 medulloblastoma 18 | 4,104
Breast cancer 17 | 3,578
adult high grade glioma 16 | 3,801
ependymoma 16 | 4,679
astrocytic glioma 14 | 2,597
lung cancer 14 | 4,740
psoriasis 14 | 6,694
Cancer 13 | 2,499
malignant mesothelioma 13 | 3,232
non-small cell lung cancer 13 | 2,890
oligodendroglioma 13 | 2,850
Kidney cancer 12 | 2,613
primitive neuroectodermal tumor 12 | 3,035
Astrocytoma, Pilocytic 11 | 3,081
invasive ductal carcinoma 11 | 2,951
interstitial cystitis 10 | 2,312
lung carcinoma 10 | 2,843
pancreatic cancer 10 | 2,398
pituitary cancer 10 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Cleft Lip 8 | 141
ductal carcinoma in situ 8 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
ulcerative colitis 7 | 1,819
Cleft Palate 6 | 271
Pick disease 6 | 1,894
Skin cancer 6 | 469
colon cancer 6 | 1,478
lung adenocarcinoma 6 | 2,716
subependymal giant cell astrocytoma 6 | 2,287
Atopic dermatitis 5 | 952
acute quadriplegic myopathy 5 | 1,158
cystic fibrosis 5 | 1,696
group 4 medulloblastoma 5 | 1,855
Autosomal recessive predisposition 4 | 1,442
Breast Neoplasms 4 | 445
Colorectal Neoplasms 4 | 243
Depressive disorder 4 | 409
Kidney disease 4 | 430
Liver Cirrhosis, Experimental 4 | 769
Mammary Neoplasms 4 | 425
Melanoma 4 | 711
Schizophrenia 4 | 1,160
adrenocortical carcinoma 4 | 1,428
juvenile dermatomyositis 4 | 1,187
pancreatic carcinoma 4 | 562
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064
spina bifida 4 | 1,074
tuberculosis 4 | 2,010
Attention deficit hyperactivity disorder 3 | 278
Autistic Disorder 3 | 364
Conductive hearing loss 3 | 123
Dull intelligence 3 | 645
Intellectual disability 3 | 1,016
Liver cancer 3 | 604
Low intelligence 3 | 645
Lung Neoplasms 3 | 232
Mental Depression 3 | 333
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Osteoporosis 3 | 363
Poor school performance 3 | 645
Syndactyly 3 | 88
Syndactyly of fingers 3 | 48
Syndactyly of the toes 3 | 45
Type 2 diabetes mellitus 3 | 272
Uranostaphyloschisis 3 | 167
aldosterone-producing adenoma 3 | 665
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
non primary Sjogren syndrome sicca 3 | 891
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
sarcoidosis 3 | 370
substance-related disorder 3 | 162
Acquired scoliosis 2 | 281
Adenoma 2 | 167
Amphetamine-Related Disorders 2 | 74
Broad flat nasal bridge 2 | 236
Chronic obstructive pulmonary disease 2 | 184
Curvature of spine 2 | 282
Endometrial cancer 2 | 311
Essential Hypertension 2 | 94
Heart disease 2 | 306
Nasal bridge wide 2 | 236
Parkinson's disease 2 | 392
Polycystic ovary syndrome 2 | 360
Stomach Neoplasms 2 | 300
breast carcinoma 2 | 1,638
nasopharyngeal carcinoma 2 | 1,058
progressive supranuclear palsy 2 | 676

Tissue

Endocrine System 41 | 18,159
Nervous System 41 | 16,725
Skin and soft tissues 41 | 17,230
Digestive Tract 40 | 17,369
Female tissues 40 | 17,400
Male tissues 40 | 17,142
Liver and Pancreas 39 | 16,750
Urinary Tract 38 | 16,678
Blood and immune system 37 | 16,909
Respiratory system 36 | 16,393
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 27 | 12,091
Transcription Factor 5 | 1,400
Enzyme 3 | 4,145
Kinase 2 | 634
GPCR 1 | 408
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
Transporter 1 | 473

GWAS Trait

Orofacial clefts 41 | 41
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 59-like TMEM59L Tbio Non-IDG -1.05276 12.2 78
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Ankyrin repeat and fibronectin type-III domain-containing protein 1 ANKFN1 Tdark Non-IDG 0.06 0.71 13
Leucine-rich repeat-containing protein 7 LRRC7 Tbio Non-IDG -1.45630 31.2 41
Proliferation marker protein Ki-67 MKI67 Tbio Non-IDG -2.50106 270.3 1434
Protein FAM49A FAM49A Tdark Non-IDG 0.11 0.60 61
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Uncharacterized protein C17orf67 C17orf67 Tdark Non-IDG 0.15 0.63 6
Filamin A-interacting protein 1-like FILIP1L Tbio Non-IDG -1.01195 13.1 76
Ras-specific guanine nucleotide-releasing factor 2 RASGRF2 Tbio Non-IDG -1.31521 23.7 21