Development Level

Tbio 6 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal behavior 1 | 298
abnormal gait 1 | 69
abnormal locomotor behavior 1 | 24
abnormal retina morphology 1 | 71
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased spleen weight 1 | 10
enlarged liver 1 | 2
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating thyroxin... 1 | 7
increased circulating total pr... 1 | 28
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small seminal vesicle 1 | 10
thrombocytopenia 1 | 56
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 11 | 11,493
osteosarcoma 10 | 7,950
ovarian cancer 9 | 8,520
psoriasis 8 | 6,694
Obesity 6 | 678
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
medulloblastoma, large-cell 5 | 6,241
tuberculosis 5 | 2,010
Seizures 4 | 596
atypical teratoid / rhabdoid tumor 4 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Cognitive delay 3 | 608
Diabetes Mellitus, Type 2 3 | 142
Epilepsy 3 | 792
Global developmental delay 3 | 608
Hypertension 3 | 396
Hypertensive disease 3 | 292
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
Mental and motor retardation 3 | 608
Polycystic ovary syndrome 3 | 360
adult high grade glioma 3 | 3,801
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
nephrosclerosis 3 | 333
non primary Sjogren syndrome sicca 3 | 891
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
ulcerative colitis 3 | 1,819
Acquired flat foot 2 | 72
Acquired metabolic disease 2 | 336
Aggressive behavior 2 | 75
Aggressive reaction 2 | 75
Astrocytoma, Pilocytic 2 | 3,081
Breast Neoplasms 2 | 445
Cardiovascular system disease 2 | 246
Congenital hypoplasia of ovary 2 | 30
Congenital hypoplasia of penis 2 | 176
Cryptorchidism 2 | 296
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Dull intelligence 2 | 645
Flatfoot 2 | 73
Hypogonadism 2 | 173
Hypoplastic ovary 2 | 30
Low intelligence 2 | 645
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Muscle hypotonia 2 | 571
Physical aggression 2 | 76
Pick disease 2 | 1,894
Poor school performance 2 | 645
Recurrent respiratory infections 2 | 141
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Small head 2 | 374
Small testicle 2 | 75
Strabismus 2 | 270
Substance-Related Disorders 2 | 115
acute myeloid leukemia 2 | 783
astrocytic glioma 2 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
head and neck cancer 2 | 271
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic carcinoma 2 | 562
primary Sjogren syndrome 2 | 735
Absence of secondary sex characteristics 1 | 22
Brain cancer 1 | 30
Delayed Puberty 1 | 97
Gastrointestinal system disease 1 | 54
Hyperglycemia 1 | 137
Hypertriglyceridemia result 1 | 37
Hypotension 1 | 82
Intestinal volvulus 1 | 8
Low serum estradiol levels 1 | 22
Malignant glioma 1 | 26
Primary hypogonadism 1 | 37
Primary physiologic amenorrhea 1 | 55
Retinal disease 1 | 25

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 3 | 4,145
Ion Channel 1 | 344
Kinase 1 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

GWAS Trait

Obesity (early onset extreme) 13 | 13
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Coiled-coil domain-containing protein 77 CCDC77 Tdark Non-IDG 1.04 0.08 8
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615
Transmembrane protein 18 TMEM18 Tbio Non-IDG -1.42979 26.0 80
Phosphofurin acidic cluster sorting protein 1 PACS1 Tbio Non-IDG -1.47068 27.8 50
Protein kinase C eta type PRKCH Tchem Kinase -1.79158 65.4 184
Ninjurin-1 NINJ1 Tbio Non-IDG -1.74626 57.9 102
Phenylalanine--tRNA ligase, mitochondrial FARS2 Tchem Enzyme -2.04685 111.9 78
Sodium/calcium exchanger 1 SLC8A1 Tchem Transporter -2.52990 349.1 141
Serologically defined colon cancer antigen 8 SDCCAG8 Tbio Non-IDG -1.14555 14.3 182
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318