Development Level

Tbio 81 | 11,445
Tdark 23 | 6,588
Tchem 14 | 1,598
Tclin 5 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 7 | 979
enlarged heart 3 | 210
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
abnormal spleen morphology 2 | 55
decreased circulating glucose ... 2 | 126
decreased lymphocyte cell numb... 2 | 83
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
increased monocyte cell number 2 | 63
abnormal behavioral response t... 1 | 66
abnormal cecum morphology 1 | 7
abnormal coat- hair morphology 1 | 19
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal mouth morphology 1 | 1
abnormal pancreas morphology 1 | 13
abnormal pelvic girdle bone mo... 1 | 12
abnormal placenta size 1 | 20
abnormal sleep behavior 1 | 70
decreased KLRG1+ CD8 alpha bet... 1 | 2
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged cecum 1 | 5
enlarged kidney 1 | 14
enlarged testis 1 | 6
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased mean platelet volume 1 | 45
limb grasping 1 | 41
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small spleen 1 | 19
thrombocytopenia 1 | 56

Disease

Carcinoma 97 | 11,493
ovarian cancer 61 | 8,520
glioblastoma 57 | 5,792
medulloblastoma, large-cell 56 | 6,241
psoriasis 56 | 6,694
atypical teratoid / rhabdoid tumor 55 | 5,112
ependymoma 51 | 4,679
lung cancer 49 | 4,740
osteosarcoma 48 | 7,950
group 3 medulloblastoma 42 | 4,104
Breast cancer 41 | 3,578
adult high grade glioma 39 | 3,801
Astrocytoma, Pilocytic 38 | 3,081
primitive neuroectodermal tumor 37 | 3,035
Kidney cancer 36 | 2,613
oligodendroglioma 34 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,291
lung carcinoma 33 | 2,843
breast carcinoma 30 | 1,638
interstitial cystitis 30 | 2,312
invasive ductal carcinoma 30 | 2,951
non-small cell lung cancer 30 | 2,890
pituitary cancer 30 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
lung adenocarcinoma 27 | 2,716
astrocytic glioma 26 | 2,597
pancreatic cancer 26 | 2,398
Schizophrenia 24 | 1,160
subependymal giant cell astrocytoma 24 | 2,287
colon cancer 23 | 1,478
malignant mesothelioma 23 | 3,232
ductal carcinoma in situ 20 | 1,745
Pick disease 19 | 1,894
Liver cancer 18 | 604
group 4 medulloblastoma 18 | 1,855
tuberculosis 18 | 2,010
cystic fibrosis 17 | 1,696
adrenocortical carcinoma 16 | 1,428
primary pancreatic ductal adenocarcinoma 15 | 1,109
ulcerative colitis 14 | 1,819
Melanoma 13 | 711
cutaneous lupus erythematosus 13 | 1,057
Atopic dermatitis 12 | 952
Cancer 12 | 2,499
Endometrial cancer 12 | 311
astrocytoma 12 | 1,146
Autosomal recessive predisposition 11 | 1,442
Bipolar Disorder 11 | 666
Skin cancer 11 | 469
acute quadriplegic myopathy 11 | 1,158
juvenile dermatomyositis 11 | 1,187
pediatric high grade glioma 11 | 1,064
Duchenne muscular dystrophy 10 | 601
Rheumatoid arthritis 10 | 1,191
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
diabetes mellitus 9 | 1,728
fibroadenoma 9 | 559
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Depressive disorder 8 | 409
Mental Depression 8 | 333
Parkinson's disease 8 | 392
dermatomyositis 8 | 966
esophageal adenocarcinoma 8 | 737
nasopharyngeal carcinoma 8 | 1,058
Acquired metabolic disease 7 | 336
Alzheimer's disease 7 | 658
Amyotrophic lateral sclerosis 7 | 451
Intellectual disability 7 | 1,016
Osteoporosis 7 | 363
Substance-Related Disorders 7 | 115
Type 2 diabetes mellitus 7 | 272
active ulcerative colitis 7 | 764
acute myeloid leukemia 7 | 783
medulloblastoma 7 | 720
non-small cell lung carcinoma 7 | 317
Alcoholic Intoxication, Chronic 6 | 289
Attention deficit hyperactivity disorder 6 | 278
Autistic Disorder 6 | 364
Cardiovascular system disease 6 | 246
Liver Cirrhosis, Experimental 6 | 769
Major Depressive Disorder 6 | 301
Multiple myeloma 6 | 1,332
Prostatic Neoplasms 6 | 495
Unipolar Depression 6 | 250
head and neck cancer 6 | 271
mucosa-associated lymphoid tissue lymphoma 6 | 484
non primary Sjogren syndrome sicca 6 | 891
Amphetamine-Related Disorders 5 | 74
Epilepsy 5 | 792
Large intestine cancer 5 | 126
Obesity 5 | 678
Seizures 5 | 596
posterior fossa group B ependymoma 5 | 416
spina bifida 5 | 1,074
Becker muscular dystrophy 4 | 191
Cognitive delay 4 | 608
Cognitive disorder 4 | 50
Mental and motor retardation 4 | 608
gastric carcinoma 4 | 807

Tissue

Endocrine System 122 | 18,159
Digestive Tract 118 | 17,369
Female tissues 116 | 17,400
Male tissues 116 | 17,142
Skin and soft tissues 115 | 17,230
Liver and Pancreas 113 | 16,750
Nervous System 113 | 16,725
Blood and immune system 112 | 16,909
Urinary Tract 111 | 16,678
Respiratory system 109 | 16,393
Cardiovascular System 106 | 15,192

Target Family

Non-IDG 71 | 12,091
Enzyme 23 | 4,145
Transcription Factor 9 | 1,400
Kinase 5 | 634
Transporter 4 | 473
Epigenetic 3 | 242
GPCR 3 | 408
Ion Channel 3 | 344
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GWAS Trait

Night sleep phenotypes 123 | 123
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
Extracellular matrix protein FRAS1 FRAS1 Tbio Non-IDG -1.51346 36.5 22
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Glypican-6 GPC6 Tbio Non-IDG -1.33560 21.9 125
Doublesex- and mab-3-related transcription factor 2 DMRT2 Tdark Transcription Factor -1.38317 20.7 50
CUB and sushi domain-containing protein 1 CSMD1 Tbio Non-IDG -1.68684 47.7 0
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Sec1 family domain-containing protein 1 SCFD1 Tbio Non-IDG -1.50460 33.8 170
Serine/threonine-protein kinase PRP4 homolog PRPF4B Tchem Kinase -1.17233 14.7 144