Development Level

Tbio 76 | 11,445
Tchem 20 | 1,598
Tdark 17 | 6,588
Tclin 8 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, incomple... 9 | 499
preweaning lethality, complete... 7 | 979
abnormal embryo size 5 | 220
abnormal behavior 4 | 298
decreased lean body mass 4 | 135
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
increased circulating creatini... 3 | 38
increased mean corpuscular vol... 3 | 92
increased total body fat amoun... 3 | 134
abnormal bone structure 2 | 187
abnormal facial morphology 2 | 17
abnormal head shape 2 | 10
abnormal kidney morphology 2 | 65
abnormal liver morphology 2 | 17
decreased circulating HDL chol... 2 | 68
decreased circulating glucose ... 2 | 126
decreased circulating total pr... 2 | 49
decreased erythrocyte cell num... 2 | 62
decreased lymphocyte cell numb... 2 | 83
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating calcium ... 2 | 34
increased circulating sodium l... 2 | 71
increased circulating total pr... 2 | 28
increased grip strength 2 | 41
increased mean corpuscular hem... 2 | 96
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
increased prepulse inhibition 2 | 32
prenatal lethality prior to he... 2 | 87
thrombocytopenia 2 | 56
abnormal body wall morphology 1 | 9
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal locomotor behavior 1 | 24
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cleft palate 1 | 8
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
limb grasping 1 | 41
microphthalmia 1 | 26
polycystic kidney 1 | 15
premature death 1 | 5
short tibia 1 | 97
small superior vagus ganglion 1 | 74
tremors 1 | 39
trunk curl 1 | 16
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 82 | 11,493
osteosarcoma 76 | 7,950
ovarian cancer 72 | 8,520
glioblastoma 57 | 5,792
lung cancer 50 | 4,740
psoriasis 43 | 6,694
medulloblastoma, large-cell 42 | 6,241
Cancer 38 | 2,499
Breast cancer 36 | 3,578
ependymoma 36 | 4,679
atypical teratoid / rhabdoid tumor 35 | 5,112
adult high grade glioma 34 | 3,801
invasive ductal carcinoma 34 | 2,951
non-small cell lung cancer 32 | 2,890
pancreatic cancer 31 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,955
lung carcinoma 29 | 2,843
malignant mesothelioma 29 | 3,232
Astrocytoma, Pilocytic 28 | 3,081
lung adenocarcinoma 28 | 2,716
Kidney cancer 26 | 2,613
Rheumatoid arthritis 26 | 1,191
primitive neuroectodermal tumor 26 | 3,035
tuberculosis 26 | 2,010
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
pituitary cancer 24 | 1,972
ulcerative colitis 24 | 1,819
group 3 medulloblastoma 23 | 4,104
oligodendroglioma 23 | 2,850
interstitial cystitis 22 | 2,312
astrocytoma 21 | 1,146
juvenile dermatomyositis 20 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
subependymal giant cell astrocytoma 20 | 2,287
group 4 medulloblastoma 19 | 1,855
acute quadriplegic myopathy 18 | 1,158
astrocytic glioma 18 | 2,597
breast carcinoma 18 | 1,638
cystic fibrosis 18 | 1,696
Pick disease 16 | 1,894
acute myeloid leukemia 16 | 783
colon cancer 15 | 1,478
ductal carcinoma in situ 15 | 1,745
Crohn's disease 14 | 321
esophageal adenocarcinoma 14 | 737
hepatocellular carcinoma 14 | 547
Autosomal recessive predisposition 13 | 1,442
Multiple Sclerosis 13 | 540
diabetes mellitus 13 | 1,728
primary pancreatic ductal adenocarcinoma 13 | 1,109
Intellectual disability 12 | 1,016
Waldenstrons macroglobulinemia 12 | 765
cutaneous lupus erythematosus 12 | 1,057
Asthma 11 | 385
Multiple myeloma 11 | 1,332
Prostatic Neoplasms 11 | 495
active ulcerative colitis 11 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
mucosa-associated lymphoid tissue lymphoma 11 | 484
Anemia 10 | 365
adrenocortical carcinoma 10 | 1,428
gastric cancer 10 | 459
non primary Sjogren syndrome sicca 10 | 891
pancreatic carcinoma 10 | 562
primary Sjogren syndrome 10 | 735
spina bifida 10 | 1,074
Diarrhea 9 | 253
Dull intelligence 9 | 645
Liver cancer 9 | 604
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Obesity 9 | 678
Poor school performance 9 | 645
active Crohn's disease 9 | 922
aldosterone-producing adenoma 9 | 665
dermatomyositis 9 | 966
medulloblastoma 9 | 720
Acquired metabolic disease 8 | 336
Alzheimer's disease 8 | 658
Arthritis 8 | 290
Arthritis, Rheumatoid 8 | 174
Barrett's esophagus 8 | 182
Bipolar Disorder 8 | 666
Inflammatory bowel disease 8 | 151
Lymphoid leukemia 8 | 160
Systemic lupus erythematosus 8 | 194
pediatric high grade glioma 8 | 1,064
periodontitis 8 | 293
sarcoidosis 8 | 370
Atopic dermatitis 7 | 952
Colitis, Ulcerative 7 | 59
Coronary artery disease 7 | 268
Duchenne muscular dystrophy 7 | 601
Fever 7 | 138
Hypersensitivity reaction type II disease 7 | 253
Kidney disease 7 | 430
Lung disease 7 | 142
gastric carcinoma 7 | 807

Tissue

Endocrine System 118 | 18,159
Blood and immune system 115 | 16,909
Digestive Tract 115 | 17,369
Female tissues 115 | 17,400
Liver and Pancreas 115 | 16,750
Nervous System 115 | 16,725
Skin and soft tissues 115 | 17,230
Respiratory system 112 | 16,393
Male tissues 111 | 17,142
Urinary Tract 111 | 16,678
Cardiovascular System 107 | 15,192

Target Family

Non-IDG 56 | 12,091
Enzyme 24 | 4,145
Transcription Factor 16 | 1,400
Kinase 8 | 634
GPCR 6 | 408
Epigenetic 5 | 242
Transporter 4 | 473
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GWAS Trait

Neutrophil percentage of white... 121 | 121
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-8 CXCL8 Tchem Non-IDG -4.00745 9942.8 1115
Granulocyte colony-stimulating factor CSF3 Tbio Non-IDG -3.83212 6976.9 816
Lysozyme C LYZ Tbio Enzyme -3.66944 4460.1 533
Telomerase reverse transcriptase TERT Tchem Enzyme -3.56910 3506.4 643
Vascular cell adhesion protein 1 VCAM1 Tchem Non-IDG -3.55044 3444.1 1291
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
Methylcytosine dioxygenase TET2 TET2 Tbio Enzyme -3.26709 1777.6 290
Early activation antigen CD69 CD69 Tbio Non-IDG -3.23032 1542.7 894
Beta-2 adrenergic receptor ADRB2 Tclin GPCR -3.22695 1680.9 829