Development Level

Tbio 103 | 11,445
Tdark 22 | 6,588
Tchem 19 | 1,598
Tclin 9 | 613

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to t... 5 | 278
abnormal embryo size 4 | 220
embryonic lethality prior to o... 3 | 239
hyperactivity 3 | 148
increased grip strength 3 | 41
increased neutrophil cell numb... 3 | 46
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal coat- hair morphology 2 | 19
abnormal coat-hair pigmentatio... 2 | 64
abnormal cornea morphology 2 | 31
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
anophthalmia 2 | 33
decreased circulating amylase ... 2 | 28
decreased circulating creatini... 2 | 39
decreased fasted circulating g... 2 | 65
decreased large unstained cell... 2 | 11
decreased lymphocyte cell numb... 2 | 83
embryonic growth retardation 2 | 106
hydrometra 2 | 53
increased circulating alkaline... 2 | 122
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased monocyte cell number 2 | 63
preweaning lethality, incomple... 2 | 499
abnormal colon morphology 1 | 3
abnormal craniofacial morpholo... 1 | 33
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal ileum morphology 1 | 2
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal maxilla morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal tooth morphology 1 | 24
abnormal vitelline vasculature... 1 | 6
cataract 1 | 92
corneal opacity 1 | 32
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased thermal nociceptive ... 1 | 2
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
long tibia 1 | 25
male infertility 1 | 123
microphthalmia 1 | 26
mydriasis 1 | 6
pale yolk sac 1 | 25
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 100 | 11,493
osteosarcoma 89 | 7,950
ovarian cancer 85 | 8,520
medulloblastoma, large-cell 65 | 6,241
psoriasis 55 | 6,694
glioblastoma 53 | 5,792
lung cancer 53 | 4,740
adult high grade glioma 42 | 3,801
Cancer 39 | 2,499
atypical teratoid / rhabdoid tumor 39 | 5,112
lung carcinoma 39 | 2,843
tuberculosis 37 | 2,010
invasive ductal carcinoma 35 | 2,951
non-small cell lung cancer 35 | 2,890
Breast cancer 33 | 3,578
ependymoma 33 | 4,679
ulcerative colitis 33 | 1,819
Astrocytoma, Pilocytic 31 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
group 3 medulloblastoma 30 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
interstitial cystitis 29 | 2,312
malignant mesothelioma 29 | 3,232
lung adenocarcinoma 28 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,989
Kidney cancer 26 | 2,613
primitive neuroectodermal tumor 24 | 3,035
Asthma 23 | 385
diabetes mellitus 23 | 1,728
subependymal giant cell astrocytoma 23 | 2,287
Rheumatoid arthritis 22 | 1,191
group 4 medulloblastoma 21 | 1,855
oligodendroglioma 21 | 2,850
pancreatic cancer 21 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
Crohn's disease 19 | 321
cystic fibrosis 19 | 1,696
ductal carcinoma in situ 19 | 1,745
Multiple myeloma 18 | 1,332
astrocytic glioma 18 | 2,597
Pick disease 17 | 1,894
breast carcinoma 17 | 1,638
pituitary cancer 17 | 1,972
Atopic dermatitis 16 | 952
Prostatic Neoplasms 15 | 495
astrocytoma 15 | 1,146
colon cancer 15 | 1,478
primary Sjogren syndrome 15 | 735
Breast Neoplasms 14 | 445
Mammary Neoplasms 14 | 425
adrenocortical carcinoma 14 | 1,428
juvenile dermatomyositis 14 | 1,187
Alzheimer's disease 13 | 658
Autosomal recessive predisposition 13 | 1,442
Liver Cirrhosis, Experimental 13 | 769
Multiple Sclerosis 13 | 540
cutaneous lupus erythematosus 13 | 1,057
spina bifida 13 | 1,074
Liver cancer 12 | 604
Schizophrenia 12 | 1,160
acute myeloid leukemia 12 | 783
non primary Sjogren syndrome sicca 12 | 891
Inflammatory bowel disease 11 | 151
Waldenstrons macroglobulinemia 11 | 765
acute quadriplegic myopathy 11 | 1,158
primary pancreatic ductal adenocarcinoma 11 | 1,109
Arthritis, Rheumatoid 10 | 174
Hypereosinophilic syndrome 10 | 71
Intellectual disability 10 | 1,016
Lymphoid leukemia 10 | 160
Vascular disease 10 | 319
gastric carcinoma 10 | 807
mucosa-associated lymphoid tissue lymphoma 10 | 484
nasopharyngeal carcinoma 10 | 1,058
Allergic rhinitis 9 | 94
Autistic Disorder 9 | 364
Carcinoma, Hepatocellular 9 | 228
Celiac disease 9 | 116
Kidney disease 9 | 430
Leukemia, Myelocytic, Acute 9 | 120
Liver carcinoma 9 | 240
Melanoma 9 | 711
active Crohn's disease 9 | 922
aldosterone-producing adenoma 9 | 665
dermatomyositis 9 | 966
Chronic Lymphocytic Leukemia 8 | 262
Esophageal Neoplasms 8 | 69
Fever 8 | 138
Hypersensitivity reaction type II disease 8 | 253
Leukemia, Myeloid, Acute 8 | 105
Lung disease 8 | 142
Parkinson's disease 8 | 392
Pneumonia 8 | 174
Polycystic ovary syndrome 8 | 360
Thrombocytopenia 8 | 197
active ulcerative colitis 8 | 764
progressive supranuclear palsy 8 | 676
Arthritis 7 | 290
Bipolar Disorder 7 | 666
esophageal adenocarcinoma 7 | 737

Tissue

Endocrine System 144 | 18,159
Digestive Tract 143 | 17,369
Female tissues 143 | 17,400
Blood and immune system 141 | 16,909
Skin and soft tissues 141 | 17,230
Liver and Pancreas 140 | 16,750
Male tissues 140 | 17,142
Respiratory system 140 | 16,393
Urinary Tract 140 | 16,678
Nervous System 139 | 16,725
Cardiovascular System 132 | 15,192

Target Family

Non-IDG 79 | 12,091
Transcription Factor 28 | 1,400
Enzyme 26 | 4,145
GPCR 6 | 408
Kinase 6 | 634
Epigenetic 3 | 242
Transporter 3 | 473
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GWAS Trait

Neutrophil percentage of granu... 153 | 153
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.90906 89.8 184
Protein FAM57B FAM57B Tdark Non-IDG 0.48 0.62 20
NEDD4 family-interacting protein 1 NDFIP1 Tbio Non-IDG -1.24333 24.3 147
Juxtaposed with another zinc finger protein 1 JAZF1 Tbio Non-IDG -1.61585 42.8 94
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Suppressor of tumorigenicity 20 protein ST20 Tdark Non-IDG -1.66163 0.71 0
Transcriptional-regulating factor 1 TRERF1 Tbio Transcription Factor -0.69436 6.18 146
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.87235 796.4 248
Interleukin-1 receptor-like 1 IL1RL1 Tbio Non-IDG -2.06895 107.0 347
Krueppel-like factor 2 KLF2 Tbio Transcription Factor -2.30630 216.2 308