Development Level

Tbio 28 | 11,445
Tchem 8 | 1,598
Tclin 5 | 613
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
embryonic lethality prior to o... 2 | 239
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
small kidney 2 | 16
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal hindlimb morphology 1 | 2
abnormal limb position 1 | 3
abnormal male genitalia morpho... 1 | 3
abnormal outer ear morphology 1 | 3
abnormal posture 1 | 2
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
absent vibrissae 1 | 12
anophthalmia 1 | 33
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased circulating unsatura... 1 | 2
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged uterus 1 | 11
hydrometra 1 | 53
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
male infertility 1 | 123
microphthalmia 1 | 26
oligodactyly 1 | 1
polydactyly 1 | 7
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74

Disease

Carcinoma 33 | 11,493
ovarian cancer 23 | 8,520
medulloblastoma, large-cell 21 | 6,241
osteosarcoma 21 | 7,950
glioblastoma 20 | 5,792
atypical teratoid / rhabdoid tumor 19 | 5,112
lung cancer 18 | 4,740
Coronary artery disease 17 | 268
Cardiovascular system disease 16 | 246
psoriasis 16 | 6,694
malignant mesothelioma 14 | 3,232
Breast cancer 13 | 3,578
diabetes mellitus 12 | 1,728
group 3 medulloblastoma 12 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
invasive ductal carcinoma 12 | 2,951
Astrocytoma, Pilocytic 11 | 3,081
non-small cell lung cancer 11 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Atherosclerosis 10 | 291
Cancer 10 | 2,499
Kidney cancer 10 | 2,613
lung adenocarcinoma 10 | 2,716
subependymal giant cell astrocytoma 10 | 2,287
ulcerative colitis 10 | 1,819
adult high grade glioma 9 | 3,801
oligodendroglioma 9 | 2,850
primitive neuroectodermal tumor 9 | 3,035
adrenocortical carcinoma 8 | 1,428
cystic fibrosis 8 | 1,696
ductal carcinoma in situ 8 | 1,745
ependymoma 8 | 4,679
pancreatic cancer 8 | 2,398
tuberculosis 8 | 2,010
Myocardial Infarction 7 | 151
breast carcinoma 7 | 1,638
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
primary Sjogren syndrome 7 | 735
Autosomal recessive predisposition 6 | 1,442
Cognitive delay 6 | 608
Essential Hypertension 6 | 94
Global developmental delay 6 | 608
Kidney disease 6 | 430
Lipid metabolism disorder 6 | 114
Liver cancer 6 | 604
Mental and motor retardation 6 | 608
Obesity 6 | 678
Pick disease 6 | 1,894
Schizophrenia 6 | 1,160
Waldenstrons macroglobulinemia 6 | 765
astrocytic glioma 6 | 2,597
astrocytoma 6 | 1,146
dermatomyositis 6 | 966
esophageal adenocarcinoma 6 | 737
Cerebrovascular disease 5 | 238
Hypertensive disease 5 | 292
Liver Cirrhosis, Experimental 5 | 769
aldosterone-producing adenoma 5 | 665
colon cancer 5 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
juvenile dermatomyositis 5 | 1,187
lung carcinoma 5 | 2,843
nasopharyngeal carcinoma 5 | 1,058
pituitary cancer 5 | 1,972
Alzheimer's disease 4 | 658
Duchenne muscular dystrophy 4 | 601
Hypercholesterolemia 4 | 44
Hypertension 4 | 396
Melanoma 4 | 711
Multiple myeloma 4 | 1,332
Muscle hypotonia 4 | 571
Osteoporosis 4 | 363
Rheumatoid arthritis 4 | 1,191
Vascular disease 4 | 319
active Crohn's disease 4 | 922
medulloblastoma 4 | 720
periodontitis 4 | 293
spina bifida 4 | 1,074
Arthritis 3 | 290
Dull intelligence 3 | 645
Epilepsy 3 | 792
Heart disease 3 | 306
Increase in blood pressure 3 | 119
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Muscle Spasticity 3 | 195
Parkinson's disease 3 | 392
Poor school performance 3 | 645
Seizures 3 | 596
Short stature 3 | 531
Type 2 diabetes mellitus 3 | 272
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
nephrosclerosis 3 | 333
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676

Tissue

Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Female tissues 43 | 17,400
Respiratory system 43 | 16,393
Liver and Pancreas 42 | 16,750
Urinary Tract 42 | 16,678
Blood and immune system 41 | 16,909
Male tissues 41 | 17,142
Nervous System 41 | 16,725
Skin and soft tissues 41 | 17,230
Cardiovascular System 36 | 15,192

Target Family

Non-IDG 22 | 12,091
Enzyme 12 | 4,145
Kinase 3 | 634
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
GPCR 1 | 408
Ion Channel 1 | 344
Transporter 1 | 473

GWAS Trait

Myocardial infarction 44 | 44
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
Telomerase-binding protein EST1A SMG6 Tbio Enzyme -1.48788 32.6 37
Cadherin EGF LAG seven-pass G-type receptor 2 CELSR2 Tbio GPCR -1.22995 16.7 139
PDZ domain-containing protein 2 PDZD2 Tbio Non-IDG -1.82148 68.3 119
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Barttin BSND Tbio Non-IDG -1.67053 47.6 132
Apolipoprotein C-I APOC1 Tbio Non-IDG -2.39715 256.4 274
Inactive phospholipase C-like protein 2 PLCL2 Tbio Enzyme -0.30556 2.11 96
Putative uncharacterized protein encoded by LINC00310 LINC00310 Tdark Non-IDG 0.00000 0
Stromal cell-derived factor 1 CXCL12 Tbio Non-IDG -3.48446 3085.9 607